Articles tagged "Donors, marginal"

2021 American Transplant Congress
Optimizing Usage of High KDPI Kidneys
Y. Ng¹, C. Kling², L. Sibulesky², J. Perkins²
¹Medicine/Nephrology, University of Washington, Seattle, WA, ²Surgery/Transplant, University of Washington, Seattle, WA
*Purpose: Among recipients of high kidney donor profile index (KDPI) kidneys, it is unclear if certain recipients fair better than others. Using data from the…
2021 American Transplant Congress
Dual Lactate Clearance in the Liver Viability Assessment During Normothermic Machine Perfusion
M. Xu¹, F. Zhou¹, O. Ahmed¹, J. Shin¹, Y. Zhu¹, G. Upadhya¹, K. Byrnes², B. Wong¹, J. Kim¹, Y. Lin¹, W. Chapman¹
¹Department of Surgery, Washington University, St. Louis, MO, ²Department of Pathology and Immunology, Washington University, St. Louis, MO
*Purpose: Liver normothermic machine perfusion (NMP) has been increasingly performed as a tool of organ preservation and to evaluate donor function. The perfusate lactate clearance…
2021 American Transplant Congress
The Association Between Environmental Determinants and High KDRI Organ Offer Acceptance Ratios
A. M. Placona, C. Martinez, M. Stuart
United Network for Organ Sharing, Henrico, VA
*Purpose: Increasing the number of transplants could be realized by increasing high KDRI organ utilization. While the impact of transplant center (TXC) aggressiveness and competition…
2021 American Transplant Congress
One-year Outcomes of a Multicenter Trial of Transplantation of Hcv Viremic Kidney Donors into Hcv Uninfected Recipients
M. Sise¹, D. Goldberg², D. Schaubel³, J. Kort⁴, R. Alloway⁵, J. Friedewald⁶, R. Fontana⁷, S. Sultan⁸, N. Desai⁹, R. Chung¹, P. Reese¹⁰
¹Mass General Hospital, Boston, MA, ²U-Miami, Miami, FL, ³U. Pennsylvania, Philadelphia, PA, ⁴Abbvie, Chicago, IL, ⁵U Cincinnati, Cincinnati, OH, ⁶Northwestern U., Evanston, IL, ⁷U. Michigan, Ann Arbor, MI, ⁸Cornell, New York City, NY, ⁹Johns Hopkins, Baltimore, MD, ¹⁰U. Pennslyvania, Philadelpha, PA
*Purpose: As interest in transplantation of Hepatitis C virus (HCV)-viremic kidneys into HCV-uninfected (HCV+ to HCV- KT) recipients increases, understanding clinical outcomes beyond HCV clearance…
2021 American Transplant Congress
Use of Hepatitis B N.A.T. Positive Kidneys in Hepatitis B Immune Recipients
E. Stephenson¹, B. Nangunuri², T. McCune³
¹Nephrology and Critical Care, Eastern Virginia Medical School, Norfolk, VA, ²Eastern Virginia Medical School, Norfolk, VA, ³Nephrology, Eastern Virginia Medical School, Norfolk, VA
*Purpose: There is an increasing demand for kidney donations as roughly 4000 people die on the waitlist each year while the number of kidneys being…
2021 American Transplant Congress
The Impact of Splenectomy on Living Donor Liver Transplantation Using Small Grafts
M. Fujiki, E. Aleassa, C. Quintini, F. Aucejo, K. Sasaki, B. Eghtesad, T. Diago, D. Kwon, C. Miller, K. Hashimoto
Cleveland Clinic Foundation, Cleveland, OH
*Purpose: Simultaneous splenectomy with living donor liver transplantation (LDLT) is widely used in Asian countries to decrease the risk of small-for-size syndrome (SFSS). However, the…
2021 American Transplant Congress
Role of Ferroptosis Inhibitors in Mitigating Ischemia-Reperfusion Injury in Marginal Livers Using a Novel Protect Model
M. D. Nazzal, J. Van Nispen, A. Armstrong, V. Murali, E. Song, M. Voigt, A. Samaddar, E. Madsen, C. Manithody, J. Krebs, D. Blackall, D. Carpenter, C. Varma, J. Teckman, A. Jain
Saint Louis University, Saint Louis, MO
*Purpose: The discard rate of deceased donor livers (DDL) remains high at nearly 9% and incudes livers that are steatotic, old in age, and from…
2021 American Transplant Congress
Can Procurement Biopsy Data Tell Us Anything? The Influence of Interstitial Fibrosis on Long-term Kidney Graft Survival
D. Stewart¹, J. Foutz¹, L. Kamal², H. McGehee¹, P. Saravanane², S. Yu³, R. Yousfi², G. Gupta²
¹Research, United Network for Organ Sharing, Richmond, VA, ²Virginia Commonwealth University Health, Richmond, VA, ³Research, Virginia Commonwealth University Health, Richmond, VA
*Purpose: Biopsy findings have been shown to have a profound impact on kidney utilization decisions. Most studies of the association between procurement biopsy findings and…
2021 American Transplant Congress
Allograft Discard Risk Index for Heart Transplantation
R. M. Reul¹, A. A. Saleem¹, C. N. Keller¹, T. H. Malik¹, J. A. Goss², A. A. Rana²
¹Office of Student Affairs, Baylor College of Medicine, Houston, TX, ²Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX
*Purpose: The number of patients awaiting heart transplantation (HTx) substantially exceeds the number of donor hearts transplanted each year, yet nearly 70% of consented donor…
2021 American Transplant Congress
Transplanting Hepatitis C Infected Organs Into Uninfected Recipients: A Pharmacy Perspective
M. L. Holt, A. James, K. Gutierrez, T. Sparkman, J. Banbury, D. Jones
University of Alabama at Birmingham Hospital, Birmingham, AL
*Purpose: Due to direct acting antivirals (DAAs), hepatitis C virus (HCV) positive patients are now resources for organ transplantation in HCV negative recipients. Our institution…

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