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American Transplant Congress abstracts

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Articles tagged "Donors, marginal"

  • 2022 American Transplant Congress

    Factors Associated with Ineligible Donor Use in the United States

    L. DeRoos, B. Li, M. Lavieri, D. Hutton, N. Parikh

    University of Michigan, Ann Arbor, MI

    *Purpose: Increasing and standardizing the use of donors who do not meet the OPTN-defined eligibility criteria would increase the number of organs available for transplantation…
  • 2021 American Transplant Congress

    A Randomized, Multicenter, Blinded Study Assessing the Effects of Gaseous Nitric Oxide in an Ex Vivo System of Human Lungs

    M. G. Hartwig1, J. A. Klapper1, N. Poola2, A. Banga3, P. G. Sanchez4, J. S. Murala3, J. L. Potenziano2

    1Duke University Medical Center, Durham, NC, 2Mallinckrodt Pharmaceuticals, Bedminster, NJ, 3University of Texas Southwestern Medical Center, Dallas, TX, 4University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: The effects of nitric oxide (NO) on donor lungs during ex vivo lung perfusion (EVLP) have not been studied. We assessed whether the novel…
  • 2021 American Transplant Congress

    Normothermic-Hyperthermic Machine Perfusion Could Increase Response to Pharmacological Intervention in Mitigation of Liver Steatosis

    F. Zhou, M. Xu, G. A. Upadhya, Y. Lin, W. C. Chapman

    Surgery, Washington University in St. Louis, St. Louis, MO

    *Purpose: To study the feasibility of mitigating rat liver steatosis with ex-situ normothermic-hyperthermic machine perfusion using a multi-drug ‘defatting’ combination.*Methods: 16 male Zucker obese rats…
  • 2021 American Transplant Congress

    Marginal Allografts in Liver Transplantation Have Very Limited Impact on Length of Stay

    C. Goff1, T. Zhang1, M. McDonald1, A. Anand1, N. Galvan2, F. Kanwal3, G. Cholankeril2, R. Hernaez3, J. A. Goss4, A. Rana2

    1Department of Student Affairs, Baylor College of Medicine, Houston, TX, 2Division of Abdominal Transplantation, Michael E DeBakey Department of General Surgery, Baylor College of Medicine, Houston, TX, 3Division of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, 4Liver Center, Division of Abdominal Transplantation, Department of General Surgery, Baylor College of Medicine, Houston, TX

    *Purpose: The purpose of this study was to determine the effect on recipient length of hospital stay following transplantation with marginal allografts as specified by…
  • 2021 American Transplant Congress

    Utilization of Donor-Derived Cell-Free DNA Testing in Kidney Transplantation: Do One Month Values Have Any Prognostic Significance?

    R. J. Stratta, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, A. Mena-Gutierrez, N. Sakhovskaya, C. Jay

    Wake Forest Univ, Winston Salem, NC

    *Purpose: Percutaneous renal allograft biopsy is the current gold standard for detecting acute rejection after kidney transplantation (KT). Noninvasive tests such as plasma-based donor-derived cell-free…
  • 2021 American Transplant Congress

    Nrf2 Assessment in Discarded Liver Allografts: A Role in Allograft Function and Salvage

    O. Ahmed, M. Xu, F. Zhou, A. N. Wein, G. Upadhya, Y. Lin, W. Chapman

    Surgery, Washington University School of Medicine, Saint Louis, MO

    *Purpose: With mounting pressures to optimize organ availability for transplantation, there is a focus on reducing organ discard and attempting to resuscitate declined grafts for…
  • 2021 American Transplant Congress

    Long-term Outcomes of Donation After Cardiac Death and Living Donor Liver Transplant for Primary Sclerosing Cholangitis: An Analysis of UNOS Registry from 2002-2020

    T. Kitajima, S. Nagai, T. Ivanics, T. Shamaa, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, D. Moonka

    Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI

    *Purpose: Use of donation after circulatory death (DCD) grafts is a reported risk factor for worse outcomes after liver transplant (LT) for primary sclerosing cholangitis…
  • 2021 American Transplant Congress

    Characterizing the Early Impact of the Kidney Accelerated Placement Project on Hard-to-place Kidneys

    J. D. Motter, A. Kernodle, M. Levan, D. Segev, J. Garonzik-Wang, A. Massie

    Johns Hopkins University, Baltimore, MD

    *Purpose: In 2019, the OPTN implemented the Kidney Accelerated Placement Project (KAPP) in an effort to increase the utilization of kidneys with a high Kidney…
  • 2021 American Transplant Congress

    Impact of Deceased Donor Mode of Death and Kidney Donor Profile Index on Baseline Donor Derived Cell Free DNA in Kidney Transplant Recipients

    B. Chopra, A. Grazier, K. K. Sureshkumar

    Allegheny Health Network, Pittsburgh, PA

    *Purpose: Donor derived-cell free DNA (dd-cfDNA) is a novel serum biomarker available for earlier prediction of acute rejection in renal allograft. Baseline dd-cfDNA values are
  • 2021 American Transplant Congress

    Evaluation of Increasing Liver Discard Rate and Waiting List Drop-Off in Post-MELD Era

    R. Matsumoto1, K. Halazun2, J. Emond1, B. Samstein2, R. S. Brown Jr.2, L. Dove1, T. Kato1

    1Center for Liver Disease and Transplantation, Columbia University Irving Medical Center, New York, NY, 2Center for Liver Disease and Transplantation, Weill Cornell Medical Center, New York, NY

    *Purpose: As number of donors and transplant cases rises each year, it is important to evaluate not only post-transplant survival rate but also the organ…
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