2022 American Transplant Congress
Single Center Experience with Acute Kidney Injury Deceased Donor Kidneys from Marginal Donors
Atrium Health Wake Forest Baptist Medical Center, Winston Salem, NC
*Purpose: Many centers will selectively transplant kidneys from standard criteria donors (SCD) with terminal acute kidney injury (AKI). However, there is limited experience with transplanting…2022 American Transplant Congress
Dendritic Cell Senescence as a Key Contributor to Transplant Rejection
1Brigham and Women’s Hospital, Boston, MA, 2University of Maryland School of Medicine, Baltimore, MD
*Purpose: Intra-graft inflammation initiated by ischemia-reperfusion injury (IRI) is an unavoidable consequence of transplantation surgery and constitutes a key source of alloimmune responses. IRI leads…2022 American Transplant Congress
Prediction of Delayed Graft Function After Deceased Donor Kidney Transplantation Using Machine Learning and Sequential Donor Data
*Purpose: Delayed graft function (DGF) has been associated with adverse kidney transplant outcomes. Accurate prediction of DGF before surgery will help select organs and candidates…2022 American Transplant Congress
Dual Deceased Donor Kidney Transplants: Maximizing Utilization of Suboptimal Kidneys
Renal Transplant, Charleston Area Medical Center, Charleston, WV
*Purpose: To demonstrate that dual transplant of marginal kidneys is an underutilized strategy to minimize discard rates and mitigate organ shortage.*Methods: We compared dual kidney…2022 American Transplant Congress
A Successful Expansion of Donor Liver Supply is Feasible with the Selective Use of Older DCD Livers
Baylor Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX
*Purpose: DCD are a key way to expand the donor pool, yet many centers are hesitant about using anything but the most favorable DCD allografts,…2022 American Transplant Congress
Fibrin Deposition in Ischemic Damaged Liver Grafts and Reconditioning with Thrombolytic Therapy During Normothermic Machine Perfusion
*Purpose: Normothermic ex situ perfusion (NMP) is a novel technique for the storage and assessment of marginal livers retrieved from donors after circulatory death (DCD).…2022 American Transplant Congress
The Performance of the Kidney Donor Profile Index in Predicting Outcomes for Kidney Transplant Recipients of Standard Criteria Donors: Results from a Brazilian Single-Center Cohort Study
Nephrology Division - Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil
*Purpose: To evaluate the performance of the Kidney Donor Profile Index (KDPI) in predicting outcomes for kidney transplant recipients (KTR) of standard criteria donors (SCD)…2022 American Transplant Congress
A Patient and Family Decision Support Tool for Kidney Organ Offer Decisions
*Purpose: For kidney transplant candidates and their care team, deciding to accept a donor organ with known or potential risk factors can be stressful and…2022 American Transplant Congress
Single Center Experience Transplanting Deceased Donor Kidneys with Poor Pump Parameters
Transplant Surgery, Wake Forest Baptist Medical Center, Winston-Salem, NC
*Purpose: With the growth of marginal deceased donor (DD) kidney utilization, machine preservation or “pumping” of selected kidneys has become an increasingly important part of…2022 American Transplant Congress
Cold Stress-Induced Ferroptosis in Liver Sinusoidal Endothelial Cells Deteriorates Liver Transplant Outcomes
UCLA Medical Center, Los Angeles, CA
*Purpose: While hepatocytes are affected by ischemia-reperfusion injury (IRI) especially under normothermic stress, liver sinusoidal endothelial cells (LSECs) are particularly vulnerable to cold storage-induced IR-insult.…
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