Articles tagged "Donors, marginal"

2019 American Transplant Congress
Machine Perfusion Allows Use of High KDPI and Prolonged Cold Ischemia Time in Deceased Donors: A Single Center Effort to Decrease Discard Rates
M. Ortigosa-Goggins, J. Gaynor, A. Mattiazzi, J. Figueiro, G. Burke, G. Ciancio, G. Guerra
Miami Transplant Institute, University of Miami, Miami, FL
*Purpose: Discard rates of deceased donor kidney transplants(DDKT)rises as the kidney donor profile index(KDPI)increases,and approaches 60%for KDPI of >85%.Pulsatile machine perfusion(MP)allows use of kidneys with…
2019 American Transplant Congress
Use Of Perirenal Adipose Tissue As A Source Of Donor Cells Allowing Evaluation Of Endothelial Inflammation And Quality Of Expanded Criteria Kidneys
R. Boissier¹, L. Lyonnet², P. Francois³, M. Meunier⁴, B. Gondran-Tellier⁵, T. Legris⁶, J. Magalon⁵, C. Picard⁷, F. Dignat George⁵, E. Lechevallier⁸, G. Karsenty⁸, F. Sabatier⁹, P. Paul¹
¹INSERM 1263, Centre de recherche en cardiovasculaire et nutrition, INSERM, Aix Marseille Univ, Assistance Publique Hopitaux Marseille, Marseille, France, ²Vascular Biology and Hematology department, Assistance publique Hopitaux Marseille (AP-HM), Marseille, France, ³INSERM 1263, Centre de recherche en cardiovasculaire et nutrition, INSERM, Aix Marseille Univ., Marseille, France, ⁴Nephrology Dialysis and Renal Transplantation Center, AP-HM, Marseille, France, ⁵INSERM 1263, C2VN, INSERM, Aix Marseille Univ., Marseille, France, ⁶Nephrology Dialysis and Renal Transplantation Center, AP-HM, Marseille, France, ⁷Etablissement Français du Sang, Alpes Méditerranée, Marseille, France, ⁸Urology and Transplantation Unit , AP-HM, Marseille, France, ⁹INSERM 1263, Centre de recherche en cardiovasculaire et nutrition, INSERM, Aix Marseille Univ, Marseille, France
*Purpose: Use of expanded-criteria donor (ECD) kidneys is a perspective to overcome organ shortage. Age and donor-related co-morbidy factors are known to affect graft function…
2019 American Transplant Congress
Absence of Non Alcoholic Fatty Liver Disease in Allografts from Morbidly Obese Donors: A Marker for Success?
M. MacConmara, A. Mufti, S. Hanish, T. Kerr, P. Vagefi, C. Hwang
Surgery (Division of Surgical Transplantation), UT Southwestern, Dallas, TX
*Purpose: Livers from African-American, morbidly obese donors are less likely to be discarded. We examined the utility of pre-recovery liver biopsy as a predictive biomarker…
2019 American Transplant Congress
Expansion Of The Use Of Left Lobe Grafts In Adult Liver Transplantation In The United States: Different Strategy Between Deceased And Living Donor Grafts
M. Fujiki, H. Matsushima, K. Sasaki, C. Quintini, F. Aucejo, T. Diago, B. Eghtesad, C. Miller, K. Hashimoto
Cleveland Clinic Foundation, Cleveland, OH
*Purpose: Left-lobe grafts are underused for adult liver transplantation in the United States. Better strategy is needed to expand the use of left lobe in…
2019 American Transplant Congress
Assessing Discarded Human Liver Quality with Normothermic Ex-Vivo Liver Perfusion
F. Zhou, M. Xu, S. Garcia-Aroz, G. A. Upadhya, Y. Lin, W. C. Chapman
Surgery, Washington University in St. Louis, St. Louis, MO
*Purpose: Normothermic Ex-vivo Liver Perfusion (NELP) of livers shows promising results in overcoming injuries that occur in deceased donor liver transplantation. The effect of NELP…
2019 American Transplant Congress
An International Comparison of Kidney Utilization in the United States and United Kingdom: What Can Be Learned?
D. Stewart¹, G. Vece¹, M. Ibrahim², C. Callaghan²
¹UNOS, Richmond, VA, ²NHS, London, United Kingdom
*Purpose: International discussions in 2017 about kidney “discard rates” between transplant (TX) professionals in the US and UK led to the realization that the two…
2019 American Transplant Congress
Effectiveness Of The Vittal Viability Criteria During Ex Situ Normothermic Machine Perfusion To Discriminate Hepatobiliary Organ Injury And Investigation Of Biochemical Markers For Post-transplant Complications
Y. L. Boteon, R. Laing, J. Attard, L. Wallace, A. Smith, M. Perera, D. Mirza, H. Mergental, S. Afford
Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom
*Purpose: The VITTAL (viability testing and transplantation of marginal livers) clinical trial demonstrated that ex situ end-ischaemic normothermic machine perfusion (NMP) allows functional assessment and…
2019 American Transplant Congress
Impact of Donor Acute Kidney Injury on GFR at 1 Year
R. Heilman, A. Kumar, A. Srinivasan, M. Smith, J. Huskey, H. Khamash, A. Mathur, C. Jadlowiec, A. Moss, K. S. Reddy
Mayo Clinic, Phoenix, AZ
*Purpose: GFR 1-year after kidney transplantation is a marker for long term graft survival. The aim of this study is to determine the impact of…
2019 American Transplant Congress
Impact of Acute Kidney Injury in Elderly Deceased Donor on the Post-Transplant Clinical Outcomes
J. Kim¹, J. Lee², Y. Kim³, K. Jin⁴, S. Han⁴, Y. Hong¹, Y. Chang¹, S. Kim¹, H. Yoon⁵, C. Yang², W. Park⁴, B. Chung²
¹Internal Medicine, Daejeon St. Mary`s Hospital, Daejeon, Korea, Republic of, ²Internal Medicine, Seoul St. Mary`s Hospital, Seoul, Korea, Republic of, ³Internal Medicine, Uijeongbu St. Mary`s Hospital, Uijeongbu, Korea, Republic of, ⁴Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea, Republic of, ⁵Internal Medicine, Incheon St. Mary`s Hospital, Incheon, Korea, Republic of
*Purpose: The proportion of kidney transplantation (KT) from deceased donors (DDs) with acute kidney injury (AKI) or aged more than 60 has increased, but it…
2019 American Transplant Congress
Risk Predictive Strategy to Expand Pancreas Donor Selection
J. W. Mensink¹, K. M. Ooms - de Vries², V. A. Huurman¹, R. A. Pol³, I. P. Alwayn¹, A. E. Braat¹
¹Department of Surgery; Division of Transplantation, Leiden University Medical Center, Leiden, Netherlands, ²Dutch Transplant Foundation, Leiden, Netherlands, ³Department of Surgery; Division of Transplantation, University Medical Center Groningen, Groningen, Netherlands
*Purpose: The discrepancy between the number of patients on the waiting list and the number of donor pancreata for transplantation needs extension of accepting criteria…