Articles tagged "Donors, marginal"

2019 American Transplant Congress
Longer-Term Outcomes for Hepatitis C Virus Negative Recipients of Kidneys from Hepatitis C Virus Nucleic Acid Test Positive Donors: The THINKER Trial
P. Reese¹, P. Abt¹, E. Blumberg¹, R. Bloom¹, D. Sawinski¹, P. Porrett¹, A. Woodards¹, K. Reddy¹, V. van Deerlin¹, R. Hasz², M. Levine¹, R. McLean¹, A. Sicilia¹, D. Goldberg¹
¹University of Penn, Philadelphia, PA, ²Gift of Life, Philadelphia, PA
*Purpose: Two trials of transplanting hepatitis C virus (HCV) nucleic acid test (NAT) positive kidneys into HCV-negative recipients have been published, both with 100% HCV…
2019 American Transplant Congress
Kidney Transplants Outcomes from Deceased Donors with Acute Kidney Injury
C. Jung¹, P. Sood², R. Mehta², D. Jorgensen², M. Molinari², S. Hariharan², A. Ganoza², D. Van Der Windt², M. Wijkstrom², C. Puttarajappa², A. Tevar³
¹Korea Univ. Anam Hospital, Seoul, Korea, Republic of, ²Univ. Pittsburgh Medical Center, Pittsburgh, PA, ³Department of Surgery, Univ. Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Due to the shortage of organs for transplantation, kidney transplants (KT) from marginal donors including donors with acute kidney injury (AKI) are expanding. Although…
2019 American Transplant Congress
Trimming the Fat?: Optimizing Utilization of Liver Allografts with Macrosteatosis >30% in Recipients with MELD Scores <35
J. A. Steggerda¹, M. B. Bloom¹, T. Todo², T. V. Brennan², N. N. Nissen², A. S. Klein², I. K. Kim²
¹Surgery, Cedars-Sinai Medical Center, Los Angeles, Los Angeles, CA, ²Transplant Surgery, Cedars-Sinai Medical Center, Los Angeles, Los Angeles, CA
*Purpose: Macrosteatosis (MaS) >30% in liver allografts has been associated with increased risk of primary non-function and poor graft survival. This study assesses the influence…
2019 American Transplant Congress
Pushing the Limits: A Large Multicentric Case-Control Study Evaluating the Impact of Kidney Transplants from Expanded Criteria Donors after Controlled Circulatory Death the Limits: A Large Multicentric Case-Control Study Evaluating the Impact of Kidney Transplants from Expanded Criteria Donors after Controlled Circulatory Death
N. Toapanta¹, R. Alvarez², G. Lluís³, C. Facundo³, F. Diekmann⁴, I. Revuelta⁴, M. Meneghini², F. Moreso¹, O. Bestard²
¹Kidney Transplantation Unit, Vall d'Hebron University Hospital, Barcelona, Spain, ²Kidney Transplantation Unit, Bellvitge University Hospital- IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain, ³Kidney Transplantation Unit, Puigvert University Hospital, Barcelona, Spain, ⁴Kidney Transplantation Unit, Clinic University Hospital, Barcelona, Spain
*Purpose: Controlled donation after circulatory death (cDCD) has allowed to significantly increase the deceased donors pool. However, while excellent previous reports have been shown using…
2019 American Transplant Congress
Liver Transplant Candidates Derive a Survival Benefit from Accepting a Macrosteatotic Liver
K. Jackson, M. Bowring, C. Haugen, C. Holscher, L. Liyanage, S. Ottmann, B. Philosophe, A. Massie, D. Segev, A. Cameron, J. Garonzik-Wang
Johns Hopkins University, Baltimore, MD
*Purpose: Accepting a liver with macrosteatosis might increase the risk of adverse post-transplant outcomes, however candidates who decline must then wait for an uncertain future…
2019 American Transplant Congress
Accelerating Kidney Allocation: Simultaneously Expiring Offers
M. Kosztowski¹, M. Mankowski², S. Raghavan³, J. Garonzik-Wang¹, D. Axelrod⁴, D. L. Segev¹, S. E. Gentry¹
¹Johns Hopkins University, Baltimore, MD, ²King Abdullah University of Science and Technology, Thuwal, Saudi Arabia, ³University of Maryland, College Park, MD, ⁴University of Iowa, Iowa City, IA
*Purpose: Placing kidneys quickly might reduce discard. Additionally, a faster allocation system that reduces cold ischemia time would yield benefits: decreased delayed graft function, shorter…
2019 American Transplant Congress
Integrated Analysis of Messenger RNA and Micro RNA Profiles in Fatty Liver Donors: Molecular Networks during Ischemia Reperfusion Injury
D. Maluf¹, A. Bajwa¹, S. K. Satapathy², V. Sai Bontha¹, A. Kadimella¹, J. Eason³, V. Mas⁴
¹UTHSC, Memphis, TN, ²UTHSC, memphis, TN, ³Director of Transplant Institute - UTHSC, Memphis, TN, ⁴Director of Transplant Research Institute, Memphis, TN
*Purpose: Liver steatosis is a known risk factor for exacerbated ischemia-reperfusion injury (IRI) and poor outcomes after liver transplantation (LT). RNA profiling was performed to…
2019 American Transplant Congress
Impact of Multidrug-Resistant Organisms among Donors on Organ Utilization
J. A. Anesi¹, E. Lautenbach¹, J. H. Han¹, D. H. Lee², H. Clauss³, A. Climaco⁴, R. Hasz⁵, E. Molnar³, D. Alimenti¹, S. West⁵, W. B. Bilker¹, P. Tolomeo¹, E. A. Blumberg¹
¹University of Pennsylvania, Philadelphia, PA, ²Drexel University College of Medicine, Philadelphia, PA, ³Temple University, Philadelphia, PA, ⁴Albert Einstein Medical Center, Philadelphia, PA, ⁵Gift of Life Donor Program, Philadelphia, PA
*Purpose: Though transplant guidelines recommend exercising caution when considering donor organs that may be infected or colonized with multidrug-resistant organisms (MDROs), the true impact of…
2019 American Transplant Congress
Kidney Donor 70 Years Of Age Or Older – How Far Can We Go? A Registry Analysis
R. W. Gruessner, J. F. Renz, F. Tedla, A. Brar, S. Saggi, M. Salifu, A. C. Gruessner
SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: With the increasing number of patients on the kidney transplant waitlist and with improved technique and management the demand for kidneys is constantly increasing.…
2019 American Transplant Congress
Pediatric Liver Transplantation during the Opioid Epidemic: UNOS Analysis of Organ Availability and Outcomes
J. Chu¹, J. Franke², C. Almy¹, R. Annunziato², R. Arnon¹
¹Recanati/Miller Transplant Institute, Icahn School of Medicine at Mount Sinai, New York, NY, ²Psychology, Fordham University, New York, NY
*Purpose: The opioid epidemic has been largely responsible for the 3-fold increase in deaths due to drug overdose over the last 15 years. Whether this…