Articles tagged "COVID-19"

2022 American Transplant Congress
Additional Dose of SARS-CoV-2 Vaccine Increases Neutralization Capacity in Solid Organ Transplant Recipients
Y. Yoo¹, J. Husson², T. Iraguha³, S. Niederhaus⁴, X. Wen⁵, A. Crane⁵, A. Carrier⁵, J. Avruch⁵, A. Ahuja⁶, M. Mathew⁷, S. Dahiya⁸, A. P. Rapoport⁸, D. Atanackovic⁸, K. K. Saharia²
¹Inst of Human Virology, Baltimore, MD, ²Div of Infect Diseases, Univ of Maryland School of Med. and Inst of Human Virology, Baltimore, MD, ³Univ of Maryland School of Med. and Greenebaum Comprehensive Cancer Center, Baltimore, MD, ⁴Dept of Surgery, Univ of Maryland School of Med., Baltimore, MD, ⁵Dept of Surgery, Univ of Maryland Med. Center, Baltimore, MD, ⁶Dept of Medicine, Univ of Maryland Med. Center, Baltimore, MD, ⁷Div of Infect. Diseases, Univ of Maryland Med. Center, Baltimore, MD, ⁸Dept of Medicine, Univ of Maryland School of Med. and Greenebaum Comprehensive Cancer Center, Baltimore, MD
*Purpose: Solid organ transplant recipients (SOTR) develop weak antibody responses after SARS-CoV-2 vaccination. Published data on neutralizing activity of plasma, a better measure of protection,…
2022 American Transplant Congress
Invasive Fungal Infections Associated with COVID-19 Infections in Solid Organ Transplant Recipients
R. Alameer, M. Nguyen, P. Samanta
Infectious Diseases, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Invasive fungal infection (IFI) complicating Coronavirus disease of 2019 (COVID-19) has been increasingly recognized. IFI is a common opportunistic infection in solid organ transplant…
2022 American Transplant Congress
The Impact Of Monoclonal Antibody Against Sars-CoV2 And Vaccination On Outcomes In Kidney Transplant Recipients With Covid-19
N. M. Ali, V. Tatapudi, R. Chand, k. Sureau, S. Mehta, R. Montgomery
NYU Langone Transplant Institute, New York, NY
*Purpose: Solid organ transplant recipients are at high risk of morbidity and mortality from coronavirus disease 2019 (COVID-19) with mortality rates as high as 30%…
2022 American Transplant Congress
Outcomes of SARS-CoV-2 Infection in Unvaccinated Compared with One or Two Dose Vaccinated Solid Organ Transplant Recipients: A Multicenter, Matched Cohort Study
V. G. Hall¹, G. Alahmadi², J. T. Solera², T. Marinelli², H. Cardinal³, G. Ramesh Prasad⁴, S. A. De Serres⁵, D. Isaac⁶, R. Mainra⁷, C. Lamarche⁸, R. Sapir-Pichhadze⁹, S. Gilmour¹⁰, J. Matelski², A. Humar², D. Kumar²
¹University Health Network/Toronto General Hospital, Toronto, ON, Canada, ²UHN, Toronto, ON, Canada, ³Department of Medicine, UMontreal, Montreal, QC, Canada, ⁴Kidney Transplant Program, St. Michael's Hospital, Toronto, ON, Canada, ⁵Transplantation Unit, Renal division, Laval University, Quebec, QC, Canada, ⁶Division of Transplant Medicine, University of Calgary, Calgary, AB, Canada, ⁷University Health Center of Saskatchewan, Saskatoon, SK, Canada, ⁸Hôpital Maisonneuve-Rosemont Research Institute, Montreal, QC, Canada, ⁹McGill University, Montreal, QC, Canada, ¹⁰Stollery Children's Hospital, Edmonton, AB, Canada
*Purpose: It is unknown if vaccine breakthrough COVID-19 infections are milder or as severe as infections in unvaccinated solid organ transplant (SOT) recipients.*Methods: We performed…
2022 American Transplant Congress
One-Year Outcomes in Kidney Transplant Recipients with Acute Kidney Injury and COVID-19
P. Shrivastava¹, R. M. Hofmann², S. P. Norman³, D. Granger⁴, N. Khoury¹, R. Prashar¹, C. Crombez⁵, A. Patel¹, S. Nagai⁶, M. Lu⁷, M. Samaniego¹
¹Department of Medicine, Henry Ford Health System, Detroit, MI, ²Renal Associates of West Michigan, Grand Rapids, MI, ³Department of Medicine, University of Michigan, Ann Arbor, MI, ⁴Department of Surgery, Ascension St. John Hospital,, Detroit, MI, ⁵Department of Transplant Surgery, Henry Ford Health System, Detroit, MI, ⁶Department of Surgery, Henry Ford Health System, Detroit, MI, ⁷Department of Public Health Sciences, Henry Ford Health System, Detroit, MI
*Purpose: Acute kidney injury (AKI) occurs in more than half of kidney transplant recipients (KTRs) with COVID-19. The longitudinal trajectory of kidney function is unclear.…
2022 American Transplant Congress
Sars-cov2 Antibody Kinetics and Durability Three and Six Months After Two-Doses of MRNA Vaccination in Liver Transplant Recipients
A. Chang¹, A. T. Strauss¹, T. P. Chiang¹, A. Jennifer¹, H. Nicole¹, L. Zeiser¹, B. Boyarsky¹, R. Avery¹, A. Tobian¹, M. Levan¹, D. Warren¹, A. Massie¹, J. Garonzik-Wang², D. Segev¹, W. Werbel¹
¹Johns Hopkins University School of Medicine, Baltimore, MD, ²University of Wisconsin School of Medicine, Madison, WI
*Purpose: nti-spike antibody response to SARS-CoV-2 vaccination is diminished in LT recipients compared to the general population so understanding durability for those that do respond…
2022 American Transplant Congress
Impaired Cellular Immunity and Elevated Myeloid Derived Suppressor Cells in Kidney Transplant Recipients with Impaired Antibody Response to Covid-19 Vaccination
B. Nibhanupudy¹, K. Mcdonald¹, M. Angelis¹, L. T. Chin¹, P. Wai¹, R. Metzger¹, C. Ashokkumar², R. Sindhi²
¹AdventHealth Transplant Institute, Orlando, FL, ²Plexision, Inc, Pittsburgh, PA
*Purpose: To evaluate post-vaccination cellular and antibody (Ab) immunity after COVID-19 vaccination in single blood samples from 17 kidney transplant (KT) recipients who had received…
2022 American Transplant Congress
Impact of ATG Dose Reduction on Kidney Transplant Outcomes During the Covid-19 Pandemic
P. A. Than¹, F. De Leon¹, K. Jen², N. Goussous¹, R. V. Perez¹, A. X. Wang³
¹Transplant Surgery, UC Davis, Sacramento, CA, ²Pathology, UC Davis, Sacramento, CA, ³Transplant Nephrology, UC Davis, Sacramento, CA
*Purpose: During the COVID-19 pandemic, many transplant centers modified induction immunosuppression regimens. Beginning December 2020, our center reduced anti-thymocyte globulin (ATG) protocol dosing by up…
2022 American Transplant Congress
Effect of Covid-19 Diagnosis on Organ Donation and Transplantation
L. Baetje¹, A. Cheng¹, S. Sander², L. Markham², M. Ott², J. Finn², A. Wee³, K. Dyer⁴, A. Atluri¹, D. Jahandar¹, M. Moncure⁴
¹University of Missouri - Kansas City School of Medicine, Kansas City, MO, ²Midwest Transplant Network, Westwood, KS, ³Transplantation Center, Cleveland Clinic, Cleveland, OH, ⁴University Health Kansas City, Kansas City, MO
*Purpose: The coronavirus disease 2019 (COVID-19) pandemic has challenged many aspects of healthcare, including organ donation and transplantation. The purpose of this study is to…
2022 American Transplant Congress
Impact of COVID on Transplant Professionalism
A. Luxon¹, D. Brennan², F. Latif³, M. Flattery⁴, S. Aryal⁵
¹CareDx, South San Francisco, CA, ²Johns Hopkins Medical Institute, Baltimore, MD, ³Columbia University, New York, NY, ⁴Virginia Commonwealth University, Richmond, VA, ⁵Inova Fairfax Hospital, Falls Church, VA
*Purpose: Although, much has been written about COVID risk and immunization efficacy in transplant recipients, there is little data on the impact of COVID on…