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Articles tagged "COVID-19"

  • 2022 American Transplant Congress

    Simultaneous Lung and Kidney Transplant in a Young Patient with COVID-19

    M. Bitar1, J. G. Youssef2, S. Yau2, A. Goodarzi2, G. Youssef3

    1Houston Methodist Academic Pulmonary Medicine, Houston Methodist Hospital, Houston, TX, 2Houston Methodist Pulmonary Transplant Center, Houston Methodist Hospital, Houston, TX, 3Department of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX

    *Purpose: Lung transplant is the last resort for COVID-19 refractory ARDS. Dual organ transplant is seen as a relative contraindication at many institutions. We describe…
  • 2022 American Transplant Congress

    Analysis of Sars-Cov-2-Specific T-Cell Responses Using Novel Single-Cell Multiplexed Isolight in Covid-19 Convalescents

    Y. Sambandam1, J. He1, N. Vanderhyde2, L. Gallon1, J. Leventhal1, J. Mathew1

    1Northwestern University, Chicago, IL, 2IsoPlexis, Branford, CT

    *Purpose: COVID-19 has poor outcomes in transplant recipients with reduced antibody responses. However, the exact cellular immune response against SARS-CoV-2 remains largely unclear. We developed…
  • 2022 American Transplant Congress

    Third Dose of SARS-CoV-2 mRNA Vaccines Significantly Increases Delta (B.1.617.2) Variant Anti-Spike Antibody Levels in Kidney Transplant Recipients

    A. Al Jurdi1, R. B. Gassen1, T. Borges1, I. T. Lape1, L. Morena1, O. Efe1, Z. Solhjou2, R. El Fekih2, C. Kotton1, J. Azzi2, L. Riella1

    1Massachusetts General Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA

    *Purpose: Emerging SARS-CoV-2 variants may be associated with a higher risk of breakthrough infections compared to wild-type (WT) virus in kidney transplant recipients (KTRs). The…
  • 2021 American Transplant Congress

    Impaired Antibody Responses to Spike Protein Antigens of Sars-cov-2 in Solid Organ Transplant (sot) Recipients

    C. Ashokkumar1, S. Nadig2, V. Rohan2, A. Kroemer3, H. Dhani3, S. Rao4, R. Sindhi5

    1Plexision, pittsburgh, PA, 2Medical University of South Carolina, Charleston, SC, 3MedStar Georgetown Transplant Institute, Georgetown, DC, 4DHR Health Institute for Research and Development, Texas, TX, 5University of Pittsburgh, Pittsburgh, PA

    *Purpose: Chronic immunosuppression can impair antibody responses after natural infection and vaccination in SOT recipients. It is not known whether antibody responses are impaired in…
  • 2021 American Transplant Congress

    Monoclonal Antibodies for Covid-19 in Patients with Solid Organ Transplant Recipients

    L. Hasan1, H. Hardgrave2, T. Osborn3, R. Dare1, L. Burdine4, E. Giorgakis4, J. Rico1

    1Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 2University of Arkansas for Medical Sciences, Little Rock, AR, 3Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, 4Transplant surgery, University of Arkansas for Medical Sciences, Little Rock, AR

    *Purpose: The FDA has issued Emergency Use Authorization (EUA) for monoclonal antibodies for the treatment of mild to moderate COVID-19 in patients at risk for…
  • 2021 American Transplant Congress

    Disparities in Living Donor Follow-up During the COVID-19 Emergency Suspension of OPTN Follow-up Reporting Requirements

    S. E. Booker, A. Henderson, L. A. Cartwright, S. Taranto, D. Klassen, J. L. Wainright

    UNOS, Richmond, VA

    *Purpose: The OPTN temporarily suspended follow-up reporting requirements on 4/3/20 (retroactive to 3/13/20) in response to the COVID-19 crisis. We assessed the policy’s impact on…
  • 2021 American Transplant Congress

    Covid-19 in Renal Transplant Recipients: Experience of Lithuania

    M. Miglinas, M. M. Janušaitė, E. Ašakienė, L. Vareikienė

    Nephrology, Vilnius University Santaros clinics, Vilnius, Lithuania

    *Purpose: Renal transplant recipients are at increased susceptibility to many viral infections, including coronavirus disease 2019 (COVID-19). The purpose of this review is to define…
  • 2021 American Transplant Congress

    Liver Transplantation for COVID-19-associated Cholangiopathy

    J. Blondeel1, P. Meersseman2, N. Gilbo1, I. Jochmans1, M. Sainz-Barriga1, J. Pirenne1, D. Monbaliu1

    1Abdominal Transplantation Surgery, University Hospitals Leuven, Leuven, Belgium, 2Medical Intensive Care Unit, University Hospitals Leuven, Leuven, Belgium

    *Purpose: The hallmark viral pneumonia of coronavirus-19-disease (COVID-19) is often accompanied by important extra-pulmonary manifestations. Liver dysfunction occurs in up to 45% of COVID-19 patients,…
  • 2021 American Transplant Congress

    Nurse and Nurse Practitioner-lead Monoclonal Antibody Initiative for Solid Organ Transplant (sot) Recipients with Covid-19

    W. Cochran1, R. Avery2, D. Brennan2, N. Lawrence2, A. Brown2, S. Sullivan2, B. Adams2, M. McCarthy2, S. Ellis2, F. Naqvi2, E. Kraus2, N. Alachkar2, S. Alasfar2, F. Al Ammary2, J. Horn2, L. Hartman2, L. Fessler2, S. Purekal2, Z. Siddiqui2, D. Carter2, J. Ficke2, M. Kantsiper2, L. Boyer2, I. Gupta2, A. Gurakar2, D. Ostrander2, J. Langlee2, S. Shoham2, K. Marr2, P. Shah2

    1Johns Hopkins Comprehensive Transplant Center, Baltimore, MD, 2Johns Hopkins, Baltimore, MD

    *Purpose: Monoclonal antibody (mAB) infusion (bamlanivimab or casirivimab/imdevimab) for symptomatic, non-hypoxemic, high-risk outpatients with COVID-19 infection, is an available early intervention for COVID-19+ SOT recipients.…
  • 2021 American Transplant Congress

    Loneliness in Adults Awaiting Liver Transplantation at 7 U.S. Transplant Centers During the Covid-19 Pandemic

    K. Berry1, D. Kent1, S. Seetharaman1, R. Wong1, Y. Mohamad1, F. Yao1, M. Duarte2, B. Boyarsky3, R. Rahimi4, A. Duarte-Rojo5, M. Kappus6, M. Volk7, D. Ladner8, D. Segev3, M. McAdams-DeMarco3, E. Verna9, D. Ganger8, J. C. Lai1

    1UCSF, San Francisco, CA, 2Johns Hopkins, Baltimore, CA, 3Johns Hopkins, Baltimore, MD, 4Baylor, Dallas, TX, 5Pittsburgh, Pittsburgh, PA, 6Duke, Durham, NC, 7Loma Linda, Loma Linda, CA, 8Northwestern, Chicago, IL, 9Columbia, New York, NY

    *Purpose: Loneliness, defined by the National Academy of Medicine as “a subjective feeling of being isolated”, has recently emerged as a strong predictor of adverse…
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