Articles tagged "COVID-19"

2022 American Transplant Congress
Mandatory Vaccine Requirements in Waitlisted Transplant Patients: A Transplant Center’s Perspective – A Call to Action
M. Debroy¹, K. Andreoni¹, A. Beach², K. Chavin¹
¹University Hospitals Cleveland Medical Center/Case Western Reserve, Cleveland, OH, ²University Hospitals, Cleveland, OH
*Purpose: The global pandemic caused by the SARS Cov-2 virus has caused unprecedented, previously unthinkable changes. COVID-19 infection in transplanted patients carries an ~ 30%…
2022 American Transplant Congress
Sars-CoV-2 Antibody Response Before and After Third Dose of Homologous mRNA Vaccine in Liver Transplant Recipients
A. T. Strauss¹, A. Chang¹, J. Alejo¹, T. Chiang¹, L. Zeiser¹, N. Fortune¹, B. Boyarsky¹, R. Avery², A. A. Tobian¹, M. Levan¹, D. S. Warren¹, A. Massie³, J. Garonzik-Wang¹, D. Segev¹, W. Werbel¹
¹Johns Hopkins University, Baltimore, MD, ²Johns Hopkins, Baltimore, MD, ³Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Liver transplant (LT) recipients have a decreased response to 2 doses of SARS-CoV-2 vaccine compared to the general population, so we aimed to understand…
2022 American Transplant Congress
Antibody Response and Molecular Graft Surveillance in Kidney Transplant Recipients Following Sars-CoV-2 Vaccination
N. M. Ali¹, J. Miles², S. Mehta¹, V. Tatapudi¹, Z. Stewart¹, B. Lonze¹, M. Mangiola¹, C. DiMaggio¹, E. Weldon¹, I. Saeed¹, J. Leonard¹, R. Herati¹, J. Thomas¹, J. Michael¹, C. Hickson¹, K. Cartiera¹, R. Montgomery¹
¹Transplant Institute, NYU Langone Health, New York, NY, ²CareDx, Brisbane, NY
*Purpose: Preliminary studies suggest that kidney transplant recipients (KTRs) show diminished humoral responses to SARS-CoV-2 vaccination. Although reports of allograft rejection after SARS-CoV-2 vaccination have…
2021 American Transplant Congress
Mortality in Organ Transplant Recipients with Covid-19 Compared to Non-transplant or Waitlisted Patients: A Meta-analysis
A. H. Lerner, E. Klein, D. Farmakiotis
Rhode Island Hospital/Brown University, Providence, RI
*Purpose: Organ transplant recipients (OTR) are considered at high risk for adverse outcomes from COVID-19. However, mortality rates range from 30%. Some studies found that…
2021 American Transplant Congress
Kidney Transplantation in Times of Covid-19 – Decision Analysis in the Canadian Context
I. Yanev¹, M. Gagnon¹, M. Cheng², S. Paraskevas², D. Kumar³, A. Dragomir⁴, R. Sapir-Pichhadze⁴
¹McGill University, Montreal, QC, Canada, ²McGill University Health Centre, Montreal, QC, Canada, ³University Health Network, Toronto, ON, Canada, ⁴Research Institute of McGill University Health Centre, Montreal, QC, Canada
*Purpose: The coronavirus disease 2019 (COVID-19) pandemic significantly impacted the field of transplantation across Canada. In this study, we outline the implications of COVID-19 related…
2021 American Transplant Congress
Limited Immunogenicity of a Single Dose of Sars-cov-2 Mrna Vaccine in Solid Organ Transplant Recipients
B. Boyarsky, M. Ou, R. Greenberg, A. Teles, W. Werbel, R. Avery, A. Tobian, A. Massie, D. Segev, J. Garonzik Wang
Johns Hopkins, Baltimore, MD
*Purpose: Given substantial challenges with vaccine allocation and evidence for short-term vaccine efficacy after a single dose of SARS-CoV-2 mRNA vaccines in clinical trials, some…
2021 American Transplant Congress
Influence of Vitamin D Status on the Prognosis of Covid 19 in Patients with Kidney Transplant
J. Ugalde-Altamirano, I. Revuelta, A. Carrillo, M. Xipell, F. Cofan, N. Esforzado, E. Montagud, G. Piñeiro, A. Molina, P. Ventura, D. Cucchiari, F. Oppenheimer, F. Diekmann, J. Campistol, B. Bayes, J. Torregrosa
Nephrology, Hospital Clinic de Barcelona, Barcelona, Spain
*Purpose: The protective role of Vitamin D as an immunomodulator has been demonstrated in different pathologies included the viral etiology. This effect has been described…
2021 American Transplant Congress
Dd-cfdna Can Guide Safe Reintroduction of Immunosuppression in Kidney Transplant Recipients with Covid-19
J. Miles¹, J. Leonard², V. Tatapudi², M. Fei¹, R. Montgomery², N. M. Ali²
¹CareDx, Brisbane, CA, ²Transplant Institute, NYU Langone Health, New York, NY
*Purpose: COVID-19 infection is associated with 25% mortality in kidney transplant recipients (KTRs). Reduction of anti-metabolite immunosuppressants during the acute COVID-19 illness is a common…
2021 American Transplant Congress
Short Term Outcomes in Previously Covid Positive Living Kidney Donors and Their Recipients
R. Prashar, N. J. Khoury, M. Ramesh, A. K. Patel
Henry Ford Transplant Institute, Detroit, MI
*Purpose: Study short term outcomes of living kidney donors (LKD) who were previously infected with COVID 19, and in their recipients.*Methods: After a brief hiatus…
2021 American Transplant Congress
Detection of SARS-CoV-2 Specific Functional T Cells Using a Seven Color Flow Cytometry Assay
L. Flebbe-Rehwaldt, J. Hayden, K. Mickey, S. Manley, S. Kleiboeker
Eurofins-Viracor, Lees Summit, MO
*Purpose: The need to evaluate SARS-CoV-2 immune responses is an important clinical research focus. Detecting neutralizing antibodies is one measure of immune response, but the…