Articles tagged "COVID-19"

2022 American Transplant Congress
Multicenter Effort Assessing the Effects of COVID Infection and Vaccination on HLA Antibodies in Waitlisted Patients with ESRD
G. R. Roll¹, M. Cooper², H. Gebel³, K. M. Hitchman⁴, M. Hobeika⁵, J. Houp⁶, M. Kamoun⁷, J. Killian⁸, J. Kim⁹, V. Kumar¹⁰, M. Levine¹¹, T. Lunow-Luke¹, R. Parsons¹², D. Ranch¹³, P. Stock¹⁴, S. Yi¹⁵, R. Rajalingam¹⁶
¹UCSF Medical Center, San Francisco, CA, ²MedStar Georgetown Transplant Institute, Washington, DC, ³Emory University Hospital, Atlanta, GA, ⁴Pathology and Laboratory Medicine, University of Texas Health San Antonio, San Antonio, TX, ⁵Houston Methodist, Houston, TX, ⁶University of Alabama, Birmingham, AL, ⁷Hospital Univ of Pennsylvania, Philadelphia, PA, ⁸University of Alabama at Birmingham, Birmingham, AL, ⁹Surgery, Keck Medicine of USC, Los Angeles, CA, ¹⁰University of Alabama at Birmingham Hospital, Birmingham, AL, ¹¹University of Pennsylvania, Philadelphia, Pe, ¹²Emory University School of Medicine, Atlanta, GA, ¹³UT Health San Antonio, San Antonio, TX, ¹⁴Univ of California-San Francisco, San Francisco, CA, ¹⁵Houston Methodist Hospital, Houston, TX, ¹⁶Immunogenetics and Transplantation Laboratory (ITL), San Francisco, CA
*Purpose: Although rare, infection and vaccination have been reported to result in human leukocyte antibodies (HLA). We analyzed the effect of SARS-CoV2 infection, or COVID-19…
2022 American Transplant Congress
Transplant Graft TMA Injury Post COVID-19 Vaccination
O. Sogbein, A. Rizvi, M. Mujtaba, S. Hussain
Internal Medicine, Division of Nephrology, University of Texas Medical Branch, Galveston, TX
*Purpose: Vaccination against SARS-CoV-2 is essential. Complicating this effort are reports of a suboptimal response to the SARS-CoV-2 spike protein in patients on immunosuppressive medications…
2022 American Transplant Congress
Impact of the Second Year COVID-19 Pandemic on the U.S. Kidney Transplantation: Interrupted Time Series Analysis
E. Tantisattamo¹, N. Polpichai², P. Mutirangura³, M. Tanariyakul⁴
¹Division of Nephrology, Hypertension and Kidney Transplantation, Department of Medicine, University of California Irvine School of Medicine, Orange, CA, ²Faculty of Medicine Songklanagarin Hospital, Prince of Songkla University, Songkhla, Thailand, ³Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, ⁴Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
*Purpose: The number of kidney transplant (KT) was decreased since the COVID-19 pandemic; however, the magnitude of the pandemic on the number of U.S. KT…
2022 American Transplant Congress
Sars-cov-2 Antibody and T Cell Response After Vaccination with or without Intensified Immunosuppression Among Pediatric Renal Transplant Recipients
H. Pizzo¹, B. Shin², P. R. Soni³, S. Nadipuram³, J. Garrison², R. Zhang², S. C. Jordan², D. Puliyanda¹
¹Pediatric Nephrology, Cedars-Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, ³Pediatric Infectious Disease, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Recent data has shown poor antibody response to SARS-CoV-2 vaccination among adult kidney transplant (tx) recipients, with seroconversion ranging between 22%-58% after two mRNA…
2022 American Transplant Congress
COVID-19+ Kidney Transplant in US Veterans: An Opportunity to Increase Transplant Rates
V. E. Whittaker
Surgery, Columbia Vagelos College of Medicine and Surgery, New York, NY
*Purpose: US veterans are less likely to be transplanted. This disparity is related to donor shortage. This study seeks to increase access to transplant of…
2022 American Transplant Congress
Abnormal B Cell Profile Associated with Inadequate Antibody Response to MRNA SARS-COV-2 Vaccine Can Be Overcome with a Third Vaccine Dose in Adolescent Kidney Transplant Recipients
C. Crane, E. Phebus, L. Loop, C. Anterasian, B. Geng, E. Ingulli
Pediatrics, UCSD Rady Children's, San Diego, CA
*Purpose: mRNA SARS-CoV-2 vaccines are highly efficacious in the general population but have shown a diminished response in immunosuppressed adolescent kidney allograft recipients. We investigated…
2022 American Transplant Congress
Antibody Response to Sars- Cov -2 Mrna Vaccine in Kidney Transplant Recipients
R. Mohamed Abdul Rahman, M. Alkadi, E. Abuhelaiqa, M. Jarman, A. Nauman, O. Fituri, M. Asim, A. Hamad, H. Tohid, P. Coyle, L. Abu Raddad, H. Al-Malki
Nephrology, Hamad Medical Corporation, Doha, Qatar
*Purpose: Kidney transplant recipients are vulnerable to develop severe form of COVID19 Infection. Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine has significantly…
2022 American Transplant Congress
Pathological Changes in Kidney Allografts Associated with COVID-19 Vaccination
S. Shelton, N. Hellenga, P. Burke
Christiana Care Health System - Kidney Transplant Program, Newark, DE
*Purpose: The Coronavirus Disease 2019 (COVID-19) pandemic prompted widespread vaccination for the immunosuppressed population starting in January 2021 with minimal information on safety outcomes. The…
2022 American Transplant Congress
De Novo Donor-Specific Antibody Development in Heart Transplant Recipients Following COVID-19 Vaccination
M. Cheng¹, O. Behbahani-Nejad¹, D. Gupta²
¹Internal Medicine, Emory University School of Medicine, Atlanta, GA, ²Internal Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA
*Purpose: To determine the incidence of de novo donor-specific antibodies (DSAs) in recipients of orthotopic heart transplants (OHT) who received an mRNA vaccine against SARS-CoV-2.*Methods:…
2022 American Transplant Congress
Association Between Maintenance Immunosuppressive Regimens And Covid-19 Mortality In Kidney Transplant Recipients
A. O. Gérard¹, S. Barbosa², D. Anglicheau³, L. Couzi⁴, M. Hazzan⁵, O. Thaunat⁶, G. Blancho⁷, S. Caillard⁸, A. Sicard¹
¹Nephrology, Nice University Hospital, Nice, France, ²Institute of Molecular and Cellular Pharmacology, CNRS, Valbonne, France, ³Nephrology, Necker University Hospital, APHP, Paris, France, ⁴Nephrology, Bordeaux Pellegrin University Hospital, Bordeaux, France, ⁵Nephrology, Lille University Hospital, Lille, France, ⁶Nephrology, Edouard Herriot Hospital, Hospices civils de Lyon, Lyon, France, ⁷Nephrology, Nantes University Hospital, Nantes, France, ⁸Nephrology, Strasbourg University Hospital, Strasbourg, France
*Purpose: Kidney transplant recipients (KTR) are at increased risk of mortality from COVID-19. We conducted a cohort study among KTR from the French Solid Organ…