Articles tagged "COVID-19"

2022 American Transplant Congress
Antibody Response to 3-Dose SARS-CoV-2 mRNA Vaccination in Pediatric Solid Organ Transplant Recipients
C. X. Qin¹, S. R. Auerbach², O. Charnaya¹, L. A. Danziger-Isakov³, N. H. Ebel⁴, A. G. Feldman², E. K. Hsu⁵, J. McAteer¹, S. Mohammad⁶, E. R. Perito⁷, A. M. Thomas¹, T. P. Chiang¹, J. M. Garonzik-Wang¹, D. L. Segev¹, D. B. Mogul¹
¹Johns Hopkins University, Baltimore, MD, ²University of Colorado, Aurora, CO, ³University of Cincinnati, Cincinnati, OH, ⁴Stanford University, Palo Alto, CA, ⁵University of Washington, Seattle, WA, ⁶Northwestern University, Chicago, IL, ⁷University of California San Francisco, San Francisco, CA
*Purpose: We report the immunogenicity and safety of a third BNT162b2 vaccine in pediatric solid organ transplant recipients (pSOTRs).*Methods: Samples from pSOTRs (12-18 years) enrolled…
2022 American Transplant Congress
A New Chapter In An Evolving Pandemic: Successful Pediatric Liver Transplantation With Covid+ Donors
M. B. Goss¹, F. Munoz², E. A. Moulton³, S. Pouch⁴, S. Koohmaraie⁵, N. Moreno¹, J. Goss³, N. Galvan³
¹McGovern Medical School, Houston, TX, ²Baylor College of Medicine, Texas Children's Hospital, Houston, TX, ³Baylor College of Medicine, Houston, TX, ⁴Emory University School of Medicine, Decatur, GA, ⁵Texas Children's Hospital, Houston, TX
*Purpose: We report the first two pediatric liver transplants utilizing allografts from COVID+ donors, infected at time of organ procurement, demonstrating a pivotal step toward…
2022 American Transplant Congress
Utilization and Discard of Organs from Covid -19 Infected Donors: A Us National Registry Analysis
A. Azhar¹, I. Moinuddin¹, A. B. Gungor², M. K. Morales¹, M. Z. Molnar³, B. Tanriover², G. Gupta¹
¹Virginia Commonwealth University, Richmond, VA, ²University of Arizona, Tuscon, AZ, ³University of Utah, Salt Lake City, UT
*Purpose: Expansion of the donor pool remains a major unmet need for solid organ transplants (SOT). Early data suggests that at least some severe acute…
2022 American Transplant Congress
Clinical Outcomes In A Large Transplant Cohort Hospitalized With COVID-19: Mycophenolate Mofetil (MMF) Utilization And Mortality Trends
R. L. Gottlieb¹, M. Askar², L. Chen³, A. Chandak⁴, E. Mozaffari³, M. Thrun³, R. Haubrich³
¹Baylor Scott & White Research Institute, Dallas, TX, ²Baylor University Medical Center, Dallas, TX, ³Gilead Sciences, Foster City, CA, ⁴Certara, New York, NY
*Purpose: To characterize demographics, treatment patterns, and outcomes among 3,998 transplant patients hospitalized for COVID-19 over 16 months of the pandemic (May ’20-Aug ’21).*Methods: Adult…
2022 American Transplant Congress
Outcomes and Complications of Covid-19 in Pediatric Solid Organ Transplant Patients
L. Ott, P. Scalise, B. Kimball, A. G. Cuenca
Department of Surgery, Boston Children's Hospital, Boston, MA
*Purpose: The purpose of the study was to examine the clinical course, outcomes, and complications of COVID-19 in pediatric solid organ transplant patients from a…
2022 American Transplant Congress
Disparity In U.S. Organ Donation And Transplantation During A Global Pandemic
J. Buggs¹, K. Dhanireddy¹, A. Kumar², N. Kemmer³
¹Transplant Surgery, Tampa General Hospital, Tampa, FL, ²Morsani College of Medicine, University of South Florida, Tampa, FL, ³Transplant Hepatology, Tampa General Hospital, Tampa, FL
*Purpose: Health disparities in the United States (U.S.) have become more evident during the pandemic with disproportionate death rates in Blacks and Hispanics (with and…
2022 American Transplant Congress
Antibody Response to Sars-CoV-2 Vaccine Among Kidney Transplant Recipients: A Retrospective Cohort Study
H. Ishida¹, K. Unagami², K. Ishii³, T. Kanzawa², T. Yagisawa⁴, K. Tanabe², M. Furusawa²
¹Tokyo Women's, Tokyo, Japan, ²Tokyo Women's Medical University, Tokyo, Japan, ³Tokyo Wimen's Medical University, Tokyo, Japan, ⁴Department of Urology, Tokyo Women's Medical University, Tokyo, Japan
*Purpose: We examined a positivity of corona virus antibody in kidney transplant recipients who received two-doses BNT162B2 (mRNA) vaccination during the beginning 6 months in…
2022 American Transplant Congress
Blood Transcriptomes of Covid-19 Infected Kidney Recipients Demonstrate Frequent and Persistent Sars-cov-2 Virome Gene Expression
Z. Sun¹, M. M. Rana², A. C. Reghuvaran³, Y. A. Azzi⁴, G. Carrara⁵, S. Hartzell⁶, S. Kulkarni³, W. Zhang⁶, K. Banu³, P. Heeger⁶, E. Akalin⁴, P. Cravedi⁶, Z. Zhang⁷, M. C. Menon³
¹Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, ²Infectious Disease Director, Icahn School of Medicine at Mount Sinai, New York, NY, ³Nephrology, Yale University, New Haven, CT, ⁴Nephrology, Montefiore Medical Center, New York, NY, ⁵Clinical Research Coordinator, Icahn School of Medicine at Mount Sinai, New York, NY, ⁶Icahn School of Medicine at Mount Sinai, New York, NY, ⁷Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Kidney transplant recipients (KTRs) have poor outcomes vs non-KTRs with acute COVID-19. To provide insight into management of immunosuppression during acute COVID-19, we studied…
2022 American Transplant Congress
Preliminary Data of the Safety and Immunogenicity Protocol of Vaccination for SARS-CoV 2 in Solid Organ Transplant Patients in Argentina
S. K. Villamil Cortez¹, J. R. Geffner², L. A. Barcan³, P. Remersano², A. Smud³, A. Villamil⁴, N. C. Imperiali¹, S. R. Groppa¹, C. A. Mombelli¹, V. A. Suarez Muñoz¹, C. Belziti⁵, F. Marcelo⁶, S. Di Pietrantonio⁷, G. J. Rosa Diez¹, M. C. Giordani¹
¹Nephrology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Inmunology, INBIRS CONICET, Buenos Aires, Argentina, ³Infectology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁴Hepatology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Cardiology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁶Nephrology, IOT Clinica de Nefrologia, Misiones, Argentina, ⁷Nephrology, Hospital El Cruce - Nestor Kirchner, Buenos Aires, Argentina
*Purpose: To evaluate the safety and generation rate of Ab anti spike rate in SOT patients at 28 and 90 days after completing the Covid…
2022 American Transplant Congress
Antibody Responses to an Additional Dose of SARS-CoV-2 mRNA Vaccine in Solid Organ Transplant Recipients with and without HIV
M. Saksena¹, G. Carrara², B. Haydel², A. Azad¹, K. Srivastava¹, C. Gleason¹, K. Beach¹, L. Sominsky¹, A. Oostenink¹, G. Cai¹, J. Carreno Quiroz¹, G. Singh¹, S. Florman², C. Cordon-Cardo³, J. Aberg⁴, A. Wajnberg⁵, F. Krammer¹, V. Simon¹, M. Rana⁴
¹Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, ²Recanati/Miller Transplantation Institute, Mount Sinai Hospital, New York, NY, ³Pathology, Molecular and Cell based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, ⁴Infectious Disease, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, ⁵General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Solid organ transplant (SOT) recipients mount suboptimal immune responses to a two-dose SARS-CoV-2 mRNA vaccine series. Data regarding antibody responses in HIV and SOT…