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Articles tagged "COVID-19"

  • 2022 American Transplant Congress

    Anti-HLA Antibodies Do Not Increase in Kidney Transplant Recipients During COVID-19 Infection

    A. Girnita1, L. Wang1, P. Ahearn1, A. Colovai2, M. Fernandez-Vina1, E. Woodle3, T. Yalamarti1, M. Menon4, Y. Azzi2, M. Melcher1, R. Bray5, H. Gebel5, P. Cravedi4, J. Maltzman1, E. Akalin2

    1Stanford University, Palo Alto, CA, 2Albert Einstein College of Medicine, New York, NY, 3University of Cincinnati, Cincinnati, OH, 4Mount Sinai, New York, NY, 5Emory University Hospital, Atlanta, GA

    *Purpose: To determine if HLA allo-antibody levels are affected by COVID-19 in renal transplanted patients and to compare the immunoglobulin class and subclass profiles as…
  • 2022 American Transplant Congress

    The Impact of Frailty Syndrome on Humoral Response to SARS-CoV-2 mRNA Vaccines in Older Kidney Transplant Recipients

    M. Schmalz1, H. Vankova2, S. Rajnochova-Bloudickova1, P. Hruba3, M. Fialova4, J. Gurka5, M. Magicova1, I. Striz4, I. Zahradka1, O. Viklicky1

    1Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 2The Third Faculty of Medicine, Charles University, Prague, Czech Republic, 3Transplantation Laboratory, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 4Department of Immunology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 5Department of Information Technology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

    *Purpose: Advanced age is associated with impaired humoral immune response to SARS-CoV-2 mRNA vaccines in kidney transplant recipients (KTR), however mechanisms are poorly understood. Frailty…
  • 2022 American Transplant Congress

    Safety and Efficacy of Peri-Vaccination Antimetabolite Hold to Augment Third SARS-CoV-2 Vaccine Dose Response in Lung Transplant Recipients

    S. Frey, J. Ruck, J. Alejo, L. Barker, W. Werbel, R. Avery, D. Segev, P. Shah

    Johns Hopkins University School of Medicine, Baltimore, MD

    *Purpose: Lung transplant recipients (LTRs) are less likely than other solid organ transplant recipients (SOTRs) to develop an antibody response to SARS-CoV-2 vaccination. Mycophenolate has…
  • 2022 American Transplant Congress

    Comparison of Outcomes of Covid-19 Between Fully Vaccinated and Unvaccinated Kidney Transplant Recipients and According to the Type of M-RNA Vaccine

    F. Villanego1, M. Crespo2, V. Lopez3, S. Zarraga4, F. Oppenheimer5, L. Llinas2, A. Andres6, C. Diaz7, M. Ruiz8, F. Moreso9, A. Rodriguez-Benot10, I. Beneyto11, S. Cabello12, C. Jimenez13, C. Canal14, M. Molina15, J. Pascual6, A. Mazuecos1

    1Department of Nephrology, Hospital Puerta del Mar, Cadiz, Spain, 2Department of Nephrology, Hospital del Mar, Barcelona, Spain, 3Department of Nephrology, Hospital Regional de Malaga, Malaga, Spain, 4Department of Nephrology, Hospital de Cruces, Baracaldo, Spain, 5Department of Nephrology, Hospital Clinic, Barcelona, Spain, 6Department of Nephrology, Hospital 12 de Octubre, Madrid, Spain, 7Department of Nephrology, Hospital Central de Asturias, Oviedo, Spain, 8Department of Nephrology, Hospital Virgen de las Nieves, Granada, Spain, 9Department of Nephrology, Hospital Vall d'Hebron, Barcelona, Spain, 10Department of Nephrology, Hospital Reina Sofia, Cordoba, Spain, 11Department of Nephrology, Hospital La Fe, Valencia, Spain, 12Department of Nephrology, Hospital Son Espases, Palma de Mallorca, Spain, 13Department of Nephrology, Hospital La Paz, Madrid, Spain, 14Department of Nephrology, Fundacion Puigvert, Barcelona, Spain, 15Department of Nephrology, Hospital Germans Trias i Pujol, Badalona, Spain

    *Purpose: The evidence regarding the clinical effectiveness of COVID-19 vaccination in kidney transplant (KT) recipients is limited so far. Our purpose is to analyze the…
  • 2022 American Transplant Congress

    Rates Of Dermatology Follow-up And New Skin Cancer Diagnosis Among Solid Organ Transplant Recipients During The Covid-19 Pandemic

    R. Saranath, J. Gomez, B. Fernandez, E. Shah, S. Michalak, I. Ahronowitz

    USC Keck School of Medicine, Los Angeles, CA

    *Purpose: Solid organ transplant recipients (SOTRs) are at an elevated risk of developing non-melanoma skin cancers. Routine dermatologic surveillance has been shown to improve skin…
  • 2022 American Transplant Congress

    Pre-Vaccine Antibodies Against Seasonal Betacoronaviruses Are Associated with Decreased Antibody Response to SARS-CoV-2 mRNA Vaccination in Solid Organ Transplant Recipients

    A. Karaba1, W. Zhou1, T. Aytenfisu1, T. S. Johnston1, O. Akinde1, Y. Eby1, A. Abedon1, J. Alejo1, C. Qin1, J. Garonzik-Wang2, S. Klein1, J. Bailey1, A. Cox1, J. Blankson1, D. Segev1, A. Tobian1, W. Werbel1

    1Johns Hopkins University, Baltimore, MD, 2University of Wisconsin School of Medicine and Health, Madison, WI

    *Purpose: The impact of antigenic imprinting, when immune memory of one antigen influences the response to subsequent similar antigens, on the antibody response in solid…
  • 2022 American Transplant Congress

    Low T Cell Responsiveness in the Early Phase Of COVID-19 Associates with Progression to Severe Pneumonia in Kidney Transplant Recipients

    M. Cremoni1, S. Cuozzo1, E. Martinuzzi2, S. Barbosa2, N. Ben Hassen1, F. Massa3, E. Demonchy4, M. Durand5, O. Thaunat6, V. Esnault1, M. Lequintrec7, S. Caillard8, N. Glaichenhaus2, A. Sicard1

    1Service de Néphrologie, Dialyse, Transplantation rénale, Centre Hospitalier Universitaire de Nice, Nice, France, 2CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France, 3Université Côte d'Azur, Laboratoire de Physio-Médecine Moléculaire, Nice, France, 4Service d'Infectiologie, Centre Hospitalier Universitaire de Nice, Nice, France, 5Service d'Urologie, Centre Hospitalier Universitaire de Nice, Nice, France, 6Service de Transplantation rénale, Néphrologie et Immunologie clinique, Hôpital Edouard Herriot, Hospices civils de Lyon, Lyon, France, 7Service de Néphrologie, Dialyse, Transplantation rénale, Centre Hospitalier Universitaire Lapeyronie, Montpellier, France, 8Service de Néphrologie et Transplantation, Centre Hospitalier Universitaire de Strasbourg, Strasbourg, France

    *Purpose: Kidney transplant (KT) recipients are more prone to developing life-threatening forms of COVID-19 than the general population. Little is known about the immunological mechanisms…
  • 2022 American Transplant Congress

    Association of Chest CT Score During Acute COVID-19 Illness with Subsequent Lung Function Loss Among Lung Transplant Patients

    Q. M. Halverson, K. Batra, L. D. Mahan, M. Mohanka, A. C. Lawrence, J. Joerns, S. Bollineni, V. Kaza, I. L. Timofte, C. D. Kershaw, L. C. Terada, F. Torres, A. Banga

    University of Texas Southwestern, Dallas, TX

    *Purpose: Limited data exists on CT chest abnormalities during acute Coronavirus disease 2019 (COVID-19) infection and associated post-illness loss of lung function among lung transplant…
  • 2022 American Transplant Congress

    Vitamin D Status and Sars-cov-2 Infection in a Cohort of Renal Transplanted Patients

    A. Regalia, C. M. Alfieri, M. Campise, D. Cresseri, M. Gandolfo, P. Messa, G. Castellano

    Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico Milano, Milano, Italy

    *Purpose: Immunomodulatory and anti-inflammatory properties have been hypothesized for native vitamin D (nVD). Very little is reported about nVD and risk of Sars-CoV-2 infection (COV)…
  • 2022 American Transplant Congress

    Differences in Acceptance to the Kidney Transplant List

    J. Cotton1, K. Perry2, N. Costa3, S. Niederhaus1

    1University of Maryland School of Medicine, Baltimore, MD, 2University of Maryland Medical Center, Baltimore, MD, 3Georgetown University, Washington, DC

    *Purpose: During the COVID-19 pandemic, kidney transplant (KT) evaluations shifted from in-person evaluation (IPE) to telemedicine evaluation (TME). Given differences in access to electronics and…
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