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Articles tagged "CD3"

  • 2015 American Transplant Congress

    Sequential Monitoring and Stability of Ex Vivo-Expanded Autologous and Non-Autologous Regulatory T Cells Following Infusion in Non-Human Primates

    H. Zhang,1 H. Guo,1 L. Lu,1 A. Zahorchak,1 R. Wiswman,2 G. Raimondi,1 D. Cooper,1 M. Ezzelarab,1 A. Thomson.1

    1University of Pittsburgh, pittsburgh, PA; 2University of Wisconsin, Madison.

    Ex vivo-expanded cynomolgus monkey CD4+CD25+CD127- regulatory T cells (Treg) maintained Foxp3 demethylation status at the Treg-Specific Demethylation Region (TSDR), and potently suppressed T cell proliferation…
  • 2015 American Transplant Congress

    Clinically Relevant Anti-TCR mAb Induction Plus Brief Rapamycin Therapy Can Achieve Long-Term Vascularized Composite Allograft (VCA) Survival

    L. Wang, A. Samanta, J. Huang, T. Bhatti, Z. Wang, R. Han, L. Levin, M. Levine, W. Hancock.

    CHOP/UPenn, Philadelphia.

    Aim: Current strategies for management of VCA recipients are adapted from solid organ transplant protocols, and almost universally employ induction therapy followed by maintenance triple…
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