ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Cadaveric organs"

  • 2020 American Transplant Congress

    Human Organ Culture: A Novel Method for Evaluation of Reperfusion Injury in Human Kidney

    J. T. Langford1, C. Edwards1, J. DiRito2, M. Harris1, S. A. Hosgood3, M. L. Nicholson3, J. S. Pober4, D. Haakinson1, G. T. Tietjen1

    1Department of Surgery, Yale School of Medicine, New Haven, CT, 2Department of Biomedical Engineering, Yale University, New Haven, CT, 3Department of Surgery, University of Cambridge, Cambridge, United Kingdom, 4Department of Immunobiology, Yale School of Medicine, New Haven, CT

    *Purpose: Evaluate the ability of human organ culture to assess protein secretion during a model of reperfusion injury.*Methods: Biopsies are obtained from transplanted-declined human kidneys…
  • 2020 American Transplant Congress

    Easier Said Than Done? Stated versus Actual Usage of Less-Than-Ideal Kidneys

    D. Stewart, H. McGehee, J. Rosendale, D. Klassen

    United Network for Organ Sharing, Richmond, VA

    *Purpose: Despite long candidate waiting times and a persistent supply to demand gap, less-than-ideal (LTI) kidneys continue to be underutilized in the U.S. Usage rates…
  • 2020 American Transplant Congress

    Enhancing Kidney Allograft Decision Making: An Organ Offer Simulation Study

    J. Mansy1, J. Case1, D. Stewart2, H. McGehee2, K. Lindblad2, R. Schaffer1, J. Fisher1, J. Rice1, S. Kurian1, C. Marsh1

    1Scripps Center for Organ and Cell Transplantation, La Jolla, CA, 2United Network for Organ Sharing Research Department, Richmond, VA

    *Purpose: This study was designed to identify opportunities to improve UNOS organ allocation as well as providers’ decision-making process for cadaveric kidney offers. Using its…
  • 2020 American Transplant Congress

    Getting to Yes Faster: Multifactorial Filters to Reduce Unwanted Offers

    A. Toll, H. McGehee, J. Rosendale, D. Stewart, R. McTier

    United Network for Organ Sharing, Richmond, VA

    *Purpose: Evaluate if multifactorial filters can reduce unwanted kidney offers to centers, thereby reducing administrative burden and getting to the accepting candidate quicker.*Methods: Using recursive…
  • 2020 American Transplant Congress

    Gross Morphological Score for Deceased Donor Kidneys Can Predict Delayed Graft Function in Kidney Transplant Recipients

    M. Mandurah, M. A. Levine, A. Sener, P. Luke

    Department of Kidney Transplantation, London Health Sciences Center, London, ON, Canada

    *Purpose: Both microscopy and kidney donor profile index (KDPI) scoring systems have been used to predict kidney transplant outcomes. Utilizing gross renal morphology, we designed…
  • 2020 American Transplant Congress

    Modelling Patient Outcomes after Listing for Deceased Donor Kidney Transplantation in the UK: A Novel Technique

    M. Ibrahim1, L. Mumford1, R. Hogg1, R. Johnson1, M. Pearson2, J. Forsythe3, C. Callaghan4

    1Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, United Kingdom, 2Winton Centre for Risk Evidence and Communication, Cambridge, United Kingdom, 3NHS Blood and Transplant, Bristol, United Kingdom, 4Renal, Guy's and St Thomas' NHS Trust, London, United Kingdom

    *Purpose: Novel methods of data analysis and communication are needed to aid clinician and patient understanding of clinical outcomes. We aimed to demonstrate patient outcomes…
  • 2020 American Transplant Congress

    Impact of Organ Donor Infections on Kidney Transplant Recipient Outcomes

    M. Santarossa1, C. Muran2, S. Sanchez2, L. Heinrich2, J. Yoo3, F. Albarillo1, S. Akkina3, N. Clark1, G. Reid1

    1Department of Medicine, Division of Infectious Diseases, Loyola University Medical Center, Maywood, IL, 2Department of Pharmacy, Loyola University Medical Center, Maywood, IL, 3Department of Medicine, Division of Transplant Nephrology, Loyola University Medical Center, Maywood, IL

    *Purpose: Donor-derived infections can lead to significant morbidity and mortality in organ transplant recipients. There is variability by center on treatment of positive donor cultures…
  • 2020 American Transplant Congress

    Longer-Term Outcomes from the THINKER and EXPANDER Trials of Transplantation Using HCV-Viremic Kidneys

    V. S. Potluri1, F. Naqvi2, P. Reese1, M. Shah1, D. Brown2, S. Prenner1, A. Loupy3, A. Woodards1, P. Abt1, E. Blumberg1, J. Trofe-Clark1, D. Segev2, R. Bloom1, D. Sawinski1, C. Durand2, P. Porrett1, M. Levine1, D. Goldberg4, N. Desai2

    1University of Pennsylvania, Philadelphia, PA, 2Johns Hopkins, Baltimore, MD, 3Paris Transplant Group, Paris, France, 4University of Miami, Miami, FL

    *Purpose: The practice of transplanting HCV-viremic kidneys into HCV-negative recipients has become more common, but longer-term outcomes have not been reported. We present data on…
  • 2020 American Transplant Congress

    Tetramethylpyrazine Activated Pparγ in Resuscitating the Liver Graft Donatedafter Cardiac Death

    F. Zhen, F. Lin, Z. Lihua, L. Wenjin, X. Yan, C. Yong, Y. Qifa

    Zhongnan Hospital of Wuhan University, Wuhan, China

    *Purpose: to identify whether Tetramethylpyrazine (TMP) pretreatment can protect DCD grafts preserved during cold storage or/and HMP and transplanted.The protective mechanisms of TMP were also…
  • 2020 American Transplant Congress

    Successful Heart Utilization and Outcomes with Long-Distance Transport of Deceased Donor Hearts: One Large Organ Procurement Organization’s Five-Year Experience

    D. Adorno, C. Wells, K. O'Connor

    LifeCenter Northwest, Bellevue, WA

    *Purpose: Long-distance transport of deceased donor hearts has been associated with reduced organ utilization rates and risk of inferior outcomes. One U.S. Organ Procurement Organization’s…
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