ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Cadaveric organs"

  • 2015 American Transplant Congress

    Characteristics and Outcomes of Kidneys Procured from Donors With KDPI > 80%

    M. Doshi, I. Hall, F. Weng, B. Schroppel, J. Ficek, R. Hasz, H. Thiessen-Philbrook, R. Formica, P. Reese, C. Parikh.

    TRIBE Consortium, New Haven, CT.

    Kidneys procured from donors with KDPI>80% are often biopsied and pumped, yet frequently discarded. The accuracy of these quality assessment tools remain controversial but contribute…
  • 2015 American Transplant Congress

    Accurate Prediction of High-Resolution HLA-A, -B, -C, -DRB1 and -DQB1 Typing and Low-Resolution HLA-DQA1 Typing by Haplotype Analysis

    A. Jaramillo,1 R. Vaidya,2 M. Pando,3 S. Gaitonde.4

    1Histocompatibility & Immunogenetics Laboratory, Gift of Hope Organ & Tissue Donor Network, Itasca, IL; 2College of Pharmacy, Roseman University of Health Sciences, South Jordan, UT; 3Department of Laboratory Medicine & Pathology, Mayo Clinic, Phoenix, AZ; 4Department of Pathology, University of Illinois, Chicago, IL.

    Aim: Allele-specific HLA antibodies are commonly detected by Luminex single antigen bead assays in solid organ transplant recipients. However, high-resolution HLA typing for deceased donors…
  • 2015 American Transplant Congress

    Impact of Delayed Graft Function and Number of Dialysis Sessions on Graft Outcome After Kidney Transplantation

    L. Lehner, A. Hohberger, L. Marschke, K. Zhang, F. Halleck, D. Khadzhynov, O. Staeck, M. Dürr, D. Schmidt, L. Liefeldt, K. Budde.

    Dep.of Nephrology Charité Campus Mitte, Charité Universitätsmedizin Berlin, Berlin, Germany.

    IntroductionDelayed graft function (DGF), defined as dialysis within the first week after kidney transplantation, is a common and known risk factor for impaired renal graft…
  • 2015 American Transplant Congress

    Glomerulosclerosis Patterns Are Non-Uniform Throughout the KDPI Spectrum With Impact on Biopsy Evaluation of Kidneys for Transplant

    M. Jendrisak,1 K. Mulawa,1 M. Harmon,1 D. Cimbaluk.2

    1Gift of Hope Organ & Tissue Donor Network, Itasca, IL; 2Rush University, Chicago, IL.

    Background: The kidney donor profile index (KDPI) stratifies kidney quality with direct bearing on organ allocation and utilization. Procurement biopsy is commonly performed and factored…
  • 2015 American Transplant Congress

    Deleterious Effects in Kidney Transplant Outcomes With Pre-Organ Procurement Iodine Contrast Exposure

    F. Barrantes,1 S. Stith.2

    1Renal Medicine Associates/Presbyterian Transplant Center, Albuquerque, NM; 2Department of Economics, University of New Mexico, Albuquerque, NM.

    Background: Iodine contrast exposure is well known to cause acute kidney injury. When contrast exposure is added to hemodynamic ischemic injury its adverse effects on…
  • 2015 American Transplant Congress

    Kidney Donor Profile Index Variability in Donors With Dialysis Dependent Acute Kidney Injury and the Impact On Organ Allocation

    A. Pai,1 M. Ghanta,1 S. Rao,1 A. Gillespie,1 S. Karhadkar,2 K. Lau,2 A. Di Carlo,2 S. Constantinescu,1 I. Lee.1

    1Nephrology, Temple Univesity School of Medicine, Philadelphia, PA; 2Surgery, Temple Univesity School of Medicine, Philadelphia, PA.

    Kidney Donor Profile Index (KDPI) is calculated using 10 donor variables including terminal serum creatinine (Cr) and is used in the new kidney allocation system…
  • 2015 American Transplant Congress

    Relationship Between Delayed Graft Function (DGF) Severity and Predicted DGF Risk

    E. Squiers,1 B. Irish,1 D. Odenheimer,1 S. Erlich,1 J. Grinyo, S. Feng, On Behalf of Quark DGF Study Investigators.

    1Quark, Fremont; 2UCSF, SF; 3U of Barcelona, BCN, Spain.

    Historically, dialysis required in the first post-transplant (TX) week has defined DGF. This incidence-based definition fails to discriminate between short versus long courses of dialysis…
  • 2015 American Transplant Congress

    Validating Outcomes Reported to the Organ Procurement and Transplantation Network for Deceased Donor Kidney Recipients

    V. Potluri,1 C. Parikh,2 I. Hall,2 J. Ficek,2 M. Doshi,3 I. Butrymowicz,2 F. Weng,4 B. Schröppel,5 H. Thiessen-Philbrook,6 P. Reese.7

    1Lankenau Hospital, Philadelphia; 2Yale University School of Medicine, New Haven; 3Wayne State University, Detroit; 4Barnabas Health, Livingston, NJ; 5University Hospital, Ulm, Germany; 6Western University, Ontario, Canada; 7University of Pennsylvania, Philadelphia.

    Data reported to the Organ Procurement and Transplantation Network (OPTN) is used in kidney transplant research, quality metrics and in policy development, but the accuracy…
  • 2015 American Transplant Congress

    Biomarkers of Deceased Donors for the Prediction of Renal Allograft Outcomes

    S. Kang,1 H. Im,1 J. Lee,1 T. Koo,1 S. Lee,2 S. Park,3 S.-J. Kim,4 C. Ahn,1 J. Yang.1

    1Transplantation Center, Seoul National University Hospital, Seoul, Republic of Korea; 2Chonbuk National University Hospital, Jeonju, Republic of Korea; 3Inje University Busan Paik Hospital, Busan, Republic of Korea; 4Samsung Medical Center, Seoul, Republic of Korea.

    Background: Better prognostic markers in deceased donors(DD) are needed for determining whether to accept suboptimal DD kidneys or predicting post-transplant outcomes. Recently, neutrophil gelatinase-associated lipocalin(NGAL),…
  • 2015 American Transplant Congress

    Histopathological Criteria for Elevated Risk of Delayed Graft Function in German Pretransplantation Kidney Biopsies from Deceased Donors

    J. Becker,1 B. Eggers,2 P. Mertens,3 A. Schwarz,4 C. Chatzikyrkou.3

    1Institute of Pathology, University Hospital of Cologne, Cologne, North Rhine-Westfalia, Germany; 2Deutsche Stiftung Organtransplantation, Frankfurt, Hesse, Germany; 3Department of Nephrology and Hypertension, Diabetology and Endocrinology, University Hospital of Magdeburg, Magdeburg, Saxonia-Anhalt, Germany; 4Clinic for Nephrology and Hypertension, Hannover Medical School, Hannover, Lower Saxony, Germany.

    Introduction:Delayed graft function (DGF) is more frequent with so called marginal kidney donors. Moreover, it is linked to increased recipient mortality and inferior transplant outcome.…
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