ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Cadaveric organs"

  • 2015 American Transplant Congress

    Gene Expression Profiles Indicate That Many Discarded Kidneys Are Potentially Transplantable

    K. Famulski,1 S. Niederhaus,2 J. Reeve,1 J. Bromberg,2 P. Halloran.

    1University of Alberta, Edmonton, Canada; 2University of Marlyland, Baltimore.

    We previously showed that the molecular kidney injury-repair response (AKI score) in implantation core biopsies (Bx) predict future graft function better than histology. This could…
  • 2015 American Transplant Congress

    Tissue Distribution, Preparation and Phenotype Characteristics of Stem Cells Originated from the Organs of Deceased Human Individuals

    A. Klimczak,1 T. Jurek,2 M. Czuba,2 U. Kozlowska,1 M. Rorat,2 K. Wrzeszcz.1

    1Institute of Immunology and Experimental Therapy Polish Academy of Sciences, Wroclaw, Poland; 2Department of Forensic Medicine, Medical University, Wroclaw, Poland.

    Objective: Multipotent stem cells are unique cells present in several human organs that have self-renewing properties and are able to differentiate into diverse specialized cell…
  • 2015 American Transplant Congress

    Screening for West Nile Virus in California: Resolving IgM Anti-WNV in the Area With Dengue Seroprevalence

    C. Chinchilla-Reyes,1,2 D. Tanglao,1 T. Mone,3 M. Koss,1 M. Nowicki.1,2

    1Viracor-IBT Laboratories, Los Angeles; 2Mendez National Institute of Transplantation Foundation, Los Angeles; 3OneLegacy, Los Angeles.

    West Nile Virus (WNV) symptoms develop 2-15 days after exposure with a short period of viremia (6-7 days). It is possible to detect WNV in…
  • 2015 American Transplant Congress

    Do Pre-Procurement Factors Affect Vascular Resistance During Pulsitile Perfusion of Deceased Donor Kidneys?

    H. Kay,1 S. Gates,2 P. Shragg,2 L. Stocks,2 D. McKay,2 R. Steiner.2

    1Rice University, Houston, TX; 2Lifesharing OPO of San Diego, University of California at San Diego, San Diego, CA.

    Background: Pulsatile perfusion (PP) of explanted deceased donor kidneys can improve early function after transplantation, as compared to static cold flushing and storage. High vascular…
  • 2015 American Transplant Congress

    Surgical Error: A Common, Preventable Threat to Deceased Donor Organs

    A. Friedman,1 T. Diflo,2 S. Florman,3 L. Ratner,4 E. Marquez,1 W. Tajik.1

    1New York Organ Donor Network, New York, NY; 2Westchester Medical Center, Valhalla, NY; 3Mount Sinai School of Medicine, New York, NY; 4Columbia Presbyterian Medical Center, New York, NY.

    Deceased donor procurements (N = 340) performed through a single organ procurement organization during a 19 month period from 7/1/13 - 11/30/14 were reviewed through…
  • 2015 American Transplant Congress

    In Pre-Implantation Biopsies Expression of Micro RNAs Is Not a Good Surrogate for Established mRNA Markers of Kidney Injury

    K. Famulski,1 S. Niederhaus,2 J. Reeve,1 J. Bromberg,2 P. Halloran.1

    1University of Alberta, Edmonton, Canada; 2University of Marlyland, Baltimore.

    Kidneys from brain dead donors>50 years old are often discarded based on conventional (clinical and histologic) criteria, despite their poor predictive value for subsequent performance…
  • 2015 American Transplant Congress

    Disparities in Death and Delisting on the Waitlist for Renal Transplant in the United States

    D. Keith, A. Nishio Lucar, G. Vranic.

    Medicine, University of Virginia, Charlottesville, VA.

    Waiting time to kidney transplant varies dramatically among organ procurement organizations (OPOs) in the US. We sought to evaluate the association between death and delisting…
  • 2015 American Transplant Congress

    Impact of Machine Perfusion After Long Static Cold Storage On Delayed Graft Function Incidence and Duration and Time to Hospital Discharge

    A. Matos,1 M. Borrelli, Jr.,1 L. Moura Requiao,1 M. Nogueira, Jr.,1 L. Pertusier,1 G. Clarizia,1 P. Ongaro,1 S. Ximenes,1 M. Durao, Jr.,1,2 A. Pacheco-Silva.1,2

    1Transplantation, Hospital Israelita Albert Einstein, Sao Paulo, Brazil; 2Medicine/Nephrology, Escola Paulista de Medicina, UNIFESP, Sao Paulo, Brazil.

    Our transplant center is not involved in organ harvesting and usually we receive a kidney for transplant with more then 20 hours of static cold…
  • 2015 American Transplant Congress

    Characteristics and Outcomes of Kidneys Procured from Donors With KDPI > 80%

    M. Doshi, I. Hall, F. Weng, B. Schroppel, J. Ficek, R. Hasz, H. Thiessen-Philbrook, R. Formica, P. Reese, C. Parikh.

    TRIBE Consortium, New Haven, CT.

    Kidneys procured from donors with KDPI>80% are often biopsied and pumped, yet frequently discarded. The accuracy of these quality assessment tools remain controversial but contribute…
  • 2015 American Transplant Congress

    Accurate Prediction of High-Resolution HLA-A, -B, -C, -DRB1 and -DQB1 Typing and Low-Resolution HLA-DQA1 Typing by Haplotype Analysis

    A. Jaramillo,1 R. Vaidya,2 M. Pando,3 S. Gaitonde.4

    1Histocompatibility & Immunogenetics Laboratory, Gift of Hope Organ & Tissue Donor Network, Itasca, IL; 2College of Pharmacy, Roseman University of Health Sciences, South Jordan, UT; 3Department of Laboratory Medicine & Pathology, Mayo Clinic, Phoenix, AZ; 4Department of Pathology, University of Illinois, Chicago, IL.

    Aim: Allele-specific HLA antibodies are commonly detected by Luminex single antigen bead assays in solid organ transplant recipients. However, high-resolution HLA typing for deceased donors…
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