Articles tagged "Cadaveric organs"

2016 American Transplant Congress
Quantitative Hepatitis C Virus (HCV) RNA in Plasma and Kidney Tissue in HCV Antibody Positive Donors.
H. Shike,¹ Z. Kadry,² R. Shah,² Y. Imamura,¹ W. Greene,¹ J. Gaspari,¹ T. Riely,¹ H. Nathan,³ R. Hasz,³ A. Jain.¹
¹Surgery, Transplant, Hershey Medical Center, Hershey, PA; ²Pathology, Hershey Medical Center, Hershey, PA; ³OPO, Gift of Life Donor Program, Philadelphia, PA.
Background: Currently HCV antibody positive deceased donors renal allografts are not considered for transplantation in HCV negative recipients. With recent development of anti-HCV therapy, utilization…
2015 American Transplant Congress
Attitudes and Beliefs About Organ Donation: Focus Group Study in Arabic-Speaking Communities in Australia
A. Ralph,^1,2 A. Alyami,^3,4 R. Allen,^3,4 K. Howard,¹ J. Craig,^1,2 S. Chadban,^3,4 M. Irving,^1,2 A. Tong.^1,2
¹Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia; ²Centre for Kidney Research, Children's Hospital at Westmead, Westmead, NSW, Australia; ³Sydney Medical School, University of Sydney, Sydney, NSW, Australia; ⁴Transplantation Services, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Background: The demand for transplantable organs continues to outweigh supply across the globe, especially in the provision of deceased donor organs from ethnic minority populations.…
2015 American Transplant Congress
Pyridoxine Deficiency After Solid Organ Transplant
S. Van Arsdale,¹ S. Yost,² M. Meer,¹ S. Schoentag,¹ P. Kadambi,³ S. Habib.³
¹Department of Nutrition Services, University of Arizona Medical Center, Tucson, AZ; ²Department of Pharmacy, University of Arizona Medical Center, Tucson, AZ; ³Department of Medicine, University of Arizona College of Medicine, Tucson, AZ.
BackgroundMicronutrient deficiencies have been discussed in the literature regarding post-transplant recipients. A proposed theory is that immunosuppressive medications or altered immune system cause pyridoxine deficiency…
2015 American Transplant Congress
Cardiosphere-Derived Cells from Cadaver Can Improve Heart Function in a Model of Non-Ischaemic Dilated Cardiomyopathy
J. Wu,^1,2 Y. Sun,^1,2 M. Tan,³ D. Chi,^1,2 M. Zhang,^1,2 K. Kang,⁴ X. Jin,⁵ B. Yu.^1,2
¹Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China; ²Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China; ³Cardiology, The First Hospital of Fangshan District, Beijing, China; ⁴Cardiovascular Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China; ⁵Thoracic Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China.
Objectives: Cardiosphere-derived cells (CDCs) are mainly obtained through myocardial biopsy, and could improve cardiac function and attenuate remodeling in myocardial infarction. In this study, we…
2015 American Transplant Congress
Gene Expression Profiles Indicate That Many Discarded Kidneys Are Potentially Transplantable
K. Famulski,¹ S. Niederhaus,² J. Reeve,¹ J. Bromberg,² P. Halloran.
¹University of Alberta, Edmonton, Canada; ²University of Marlyland, Baltimore.
We previously showed that the molecular kidney injury-repair response (AKI score) in implantation core biopsies (Bx) predict future graft function better than histology. This could…
2015 American Transplant Congress
Tissue Distribution, Preparation and Phenotype Characteristics of Stem Cells Originated from the Organs of Deceased Human Individuals
A. Klimczak,¹ T. Jurek,² M. Czuba,² U. Kozlowska,¹ M. Rorat,² K. Wrzeszcz.¹
¹Institute of Immunology and Experimental Therapy Polish Academy of Sciences, Wroclaw, Poland; ²Department of Forensic Medicine, Medical University, Wroclaw, Poland.
Objective: Multipotent stem cells are unique cells present in several human organs that have self-renewing properties and are able to differentiate into diverse specialized cell…
2015 American Transplant Congress
Screening for West Nile Virus in California: Resolving IgM Anti-WNV in the Area With Dengue Seroprevalence
C. Chinchilla-Reyes,^1,2 D. Tanglao,¹ T. Mone,³ M. Koss,¹ M. Nowicki.^1,2
¹Viracor-IBT Laboratories, Los Angeles; ²Mendez National Institute of Transplantation Foundation, Los Angeles; ³OneLegacy, Los Angeles.
West Nile Virus (WNV) symptoms develop 2-15 days after exposure with a short period of viremia (6-7 days). It is possible to detect WNV in…
2015 American Transplant Congress
Do Pre-Procurement Factors Affect Vascular Resistance During Pulsitile Perfusion of Deceased Donor Kidneys?
H. Kay,¹ S. Gates,² P. Shragg,² L. Stocks,² D. McKay,² R. Steiner.²
¹Rice University, Houston, TX; ²Lifesharing OPO of San Diego, University of California at San Diego, San Diego, CA.
Background: Pulsatile perfusion (PP) of explanted deceased donor kidneys can improve early function after transplantation, as compared to static cold flushing and storage. High vascular…
2015 American Transplant Congress
Surgical Error: A Common, Preventable Threat to Deceased Donor Organs
A. Friedman,¹ T. Diflo,² S. Florman,³ L. Ratner,⁴ E. Marquez,¹ W. Tajik.¹
¹New York Organ Donor Network, New York, NY; ²Westchester Medical Center, Valhalla, NY; ³Mount Sinai School of Medicine, New York, NY; ⁴Columbia Presbyterian Medical Center, New York, NY.
Deceased donor procurements (N = 340) performed through a single organ procurement organization during a 19 month period from 7/1/13 - 11/30/14 were reviewed through…
2015 American Transplant Congress
In Pre-Implantation Biopsies Expression of Micro RNAs Is Not a Good Surrogate for Established mRNA Markers of Kidney Injury
K. Famulski,¹ S. Niederhaus,² J. Reeve,¹ J. Bromberg,² P. Halloran.¹
¹University of Alberta, Edmonton, Canada; ²University of Marlyland, Baltimore.
Kidneys from brain dead donors>50 years old are often discarded based on conventional (clinical and histologic) criteria, despite their poor predictive value for subsequent performance…