ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Brain death"

  • 2020 American Transplant Congress

    A Stroke Volume-Based Fluid Resuscitation Protocol Decreases Vasopressor Support and Increases Organ Yield in Brain-Dead Donors

    G. F. Marklin

    Mid-America Transplant, St Louis, MO

    *Purpose: Brain-dead donors are frequently hypovolemic and hypotensive requiring vasopressor support. The goal of fluid resuscitation is to increase perfusion and oxygen delivery and avoid…
  • 2020 American Transplant Congress

    Less is More: A Single Brain Death Exam Improves Organ Donation Outcomes

    A. J. Matar1, H. Wichmann2, L. Kenney2, A. Subramanian3, J. Ratcliff4, V. Patel4, B. M. Tracy2, R. B. Gelbard2

    1Surgery and Transplantation, Emory University, Atlanta, GA, 2Surgery, Emory University, Atlanta, GA, 3Surgery, Lawnwood Regional Medical Center, Fort Pierce, FL, 4Neurosurgery, Emory University, Atlanta, GA

    *Purpose: The diagnosis of brain death in adults has historically required two brain death examinations (TBD) before considering organ donation. Despite American Academy of Neurology…
  • 2020 American Transplant Congress

    A Large Animal Model of Ex-Vivo Lung Perfusion as a Platform to Deliver Therapeutic Agents to Lungs Before Lung Transplant

    T. M. Egan1, B. Haithcock1, M. H. Ali1, J. W. Blackwell1, B. Masuodi1, S. Shipley2, T. Long3, A. Akerman1, S. Montgomery4, H. Yuan5, P. Stewart6, J. Potenziano7, C. Sekaran7, R. Fitch7

    1Surgery, UNC at Chapel Hill, Chapel Hill, NC, 2Department of Pathology and Laboratory Medicine, UNC at Chapel Hill, Chapel Hill, NC, 3Pathology and Laboratory Medicine,, UNC at Chapel Hill, Chapel Hill, NC, 4Pathology and Laboratory Medicine, UNC at Chapel Hill, Chapel Hill, NC, 5Radiology, UNC at Chapel Hill, Chapel Hill, NC, 6Gillings Global School of Public Health, UNC at Chapel Hill, Chapel Hill, NC, 7Mallinckrodt Pharmaceuticals, Hazelwood, MO

    *Purpose: Ex-vivo lung perfusion (EVLP) has been used to evaluate lung function before lung transplant (LT). We used EVLP to expose lungs recovered 6 hours…
  • 2020 American Transplant Congress

    Ex Vivo Normothermic Perfusion Improves Cold Ischemic Injury and DGF in an Experimental Model of DBD Kidney Transplantation

    A. Gutierrez-Dalmau1, V. Alastrue2, Á. García De Jalon3, M. Sánchez3, C. Del Agua4, V. P. González5, Á. Roncales3, J. Gómez-Arrue6, C. Pastor6, B. Sáez7, L. M. Esteban8, M. J. Gil3, M. Doblaré9, Á. Borque-Fernando3

    1Nephrology, Hospital Universitario Miguel Servet (HUMS), IIS Aragón, Zaragoza, Spain, 2EBERS, Zaragoza, Spain, 3Urology, HUMS, Zaragoza, Spain, 4Pathology, HUMS, Zaragoza, Spain, 5Hematology, HUMS, Zaragoza, Spain, 6Experimental Surgery, IACS, Zaragoza, Spain, 7Faculty of Health Sciences, San Jorge University, Zaragoza, Spain, 8EUPLA, Zaragoza University, Zaragoza, Spain, 9Department of Mechanical Engineering, Zaragoza University, Zaragoza, Spain

    *Purpose: Cold ischemic (CI) injury results in high rates of DGF, reduced graft function and survival. Ex vivo normothermic perfusion (EVNP) has shown to improve…
  • 2020 American Transplant Congress

    Comparison of Metabolic Outcomes after Pancreas Transplantation between DBD (Donors after Brainstem Death) and DCD (Donors after Circulatory Death) Grafts

    J. Gopal, A. McLean, J. Crane, P. Herbert, F. Dor, M. Reddy, D. Taube, V. Papalois, A. Muthusamy

    Imperial College Renal and Transplant Centre, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

    *Purpose: DCD pancreas transplantation has become common with equivalent graft survival as that of DBD grafts, but are the metabolic outcomes similar? Given the lack…
  • 2020 American Transplant Congress

    Living versus Deceased Donor Liver Transplantation in Cholestatic Liver Disease: An Analysis of the OPTN Database

    I. A. Ziogas1, S. P. Alexopoulos1, L. K. Matsuoka1, S. K. Geevarghese1, L. D. Gorden1, S. J. Karp1, J. D. Perkins2, M. I. Montenovo1

    1Vanderbilt University Medical Center, Nashville, TN, 2University of Washington, Seattle, WA

    *Purpose: The current MELD allocation system does not accurately reflect the urgency of liver transplantation (LT) in cholestatic liver disease (CLD) patients. Therefore, more CLD…
  • 2019 American Transplant Congress

    Organ Donation is an Indication for Renal Replacement Therapy (RRT)

    A. L. Friedman, E. Marquez, J. A. Lewis

    LiveOnNY, New York, NY

    *Purpose: A retrospective review of cases from one large organ procurement organization (OPO) was performed to determine whether the delivery of RRT as a component…
  • 2019 American Transplant Congress

    Pancreas Transplant Alone Using Donation After Cardiac Death Donors Has Similar Outcomes As Donation After Brain Death Donors

    K. Espinoza1, D. Wall1, K. L. Lentine2, J. R. Wellen1, D. Hammad1, D. C. Brennan3, T. Alhamad1

    1Washinton University in St. Louis, St. Louis, MO, 2Saint Louis University, St. Louis, MO, 3Johns Hopkins University, St. Louis, MO

    *Purpose: While outcomes of pancreas transplants are improving, there is a persistent hesitancy to use pancreas organs procured in the context of donation after cardiac…
  • 2019 American Transplant Congress

    Staged Procedure In Simultaneous Liver And Kidney Transplant -the “Swedish” Experience

    A. Gravetz

    Transplant Surgery, Swedish Medical Center, Seattle, WA

    *Purpose: As many as 30% of liver transplant candidates have renal insufficiency requiring a combined liver and kidney transplantation. The prolonged and complex simultaneous liver-kidney…
  • 2019 American Transplant Congress

    Donor Management in Donation after Brain Death: A Window of Opportunity – Are Pro-Inflammatory Mediators the Target and What is the Effect of Duration of Brain Death?

    K. D. Bera1, J. Tabak2, M. L. Lo Faro1, R. J. Ploeg1

    1Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, 2University of Exeter, Exeter, United Kingdom

    *Purpose: Donation after brain death (BD) is a crucial source of transplanted organs - uncertainty remains how duration of BD contributes to outcomes: This study…
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