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Articles tagged "Blood transfusion"

  • 2019 American Transplant Congress

    Perioperative Blood Transfusion Significantly Increases Inpatient Morbidity and Mortality in Renal Transplant Recipients: 15-year Experience

    K. Mahendraraj1, G. Medrano del Rosal1, M. Kruse1, R. Shah1, T. Katsichtis1, T. Brennan2, N. Nissen2, T. Todo2, K. Kosari2, A. Klein2, I. Kim2

    1Surgery, Lincoln Medical Center, New York, NY, 2Transplant Surgery, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: This study evaluates the immediate effects of perioperative blood transfusion (PBT) on inpatient morbidity and mortality among renal transplant (RT) recipients during their index…
  • 2018 American Transplant Congress

    Shared HLA Specificities between the Blood and Transplant Donor Increases the Risk of De Novo DSA Development Following Blood Transfusion in Transplant Recipients

    S. Hassan,1 F. Regan,2 C. Brown,3 A. Harmer,2 N. Anderson,2 E. Santos,4 P. Brookes,4 D. Taube,1 M. Willicombe.1

    1Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; 2Haematology, Imperial College Healthcare NHS Trust, London, United Kingdom; 3Histocompatibility and Immunogenetics, NHS Blood and Transplant, London, United Kingdom; 4Histocompatibility and Immunogenetics, Imperial College Healthcare NHS Trust, London, United Kingdom.

    Introduction: Blood transfusions post-transplant have been shown to be associated with the development of de novo DSA and inferior allograft outcomes. The mechanisms behind this…
  • 2018 American Transplant Congress

    Recent Exposure to Four-Factor Prothrombin Complex Concentrate (4F-PCC) is Associated with Intracardiac Thrombus during Liver Transplantation

    M. Misel,1,2 G. Schnickel,1 J. Berumen,1 R. Sanchez,3 K. Mekeel.1

    1Division of Transplant & Hepatobiliary Surgery, UC San Diego Health, La Jolla, CA; 2Pharmacy Inpatient Services, UC San Diego Health, La Jolla, CA; 3Anesthesiology, UC San Diego Health, La Jolla, CA.

    BackgroundPatients with ESLD often have imbalance in hemostasis & monitoring traditional coagulation lab markers are generally not helpful. Intracardiac thrombus (ICT) during liver transplant (LT)…
  • 2018 American Transplant Congress

    Preoperative Anemia in Transfusion Free Patients Undergoing Kidney Transplant May Be Associated with Poor Outcome

    N. Kaur, A. Pita, C. Lane, M. Bhatnagar, L. Matsuoka, R. Selby, K. Dhanireddy.

    Department of Surgery, University of Southern California, Los Angeles, CA.

    Background: Preoperative anemia can contribute to poor outcomes in transfusion-free (TF) kidney transplants (KT). There are no established guidelines on the acceptable degree of anemia.…
  • 2018 American Transplant Congress

    Peri-Operative Hemoglobin, Blood Transfusion and Delayed Graft Function in Kidney Transplant Recipients

    S. MacIsaac, A. Ramankumar, C. Saw, V. Naessens, M. Cantarovich, D. Baran, S. Paraskevas, J. Tchervenkov, P. Chaudhury, S. Sandal.

    MUHC, Montreal, Canada.

    Background: Studies in the non-kidney transplant (KT) literature support an absolute hemoglobin concentration (Hb) threshold of 70 g/L for transfusion, unless otherwise indicated. Some reports…
  • 2017 American Transplant Congress

    Chronic Hepatitis E-Genotype 3 Infection in Transplant Recipients: A Single Kidney and Pancreas Transplant Centre Experience.

    A. Kousios,1 R. Charif,1 E. Sanchez,2 S. Khan,3 F. Regan,4 S. Ijaz,5 D. Muir,2 B. Smith,3 R. Tedder,5 D. Taube,1 J. Galliford.1

    1Renal and Transplant Centre, Imperial College NHS Trust, London, United Kingdom; 2Department of Infection and Immunity, Imperial College NHS Trust, London, United Kingdom; 3Department of Hepatology, Imperial College NHS Trust, London, United Kingdom; 4Department of Hematology, Imperial College NHS Trust, London, United Kingdom; 5Blood Borne Virus Unit, Virus Reference Department, MS-Colindale, Public Health England, London, United Kingdom

    Introduction:In the UK, Hepatitis E virus-genotype 3 (HEV3), is endemic and has now become the major cause of enterically transmitted viral hepatitis. Unlike HEV-genotype 1…
  • 2017 American Transplant Congress

    Renal Transplant Recipients with Indication for Antiplatelet Therapy: Increased Risk for the Allograft?

    T. Benko, M. Gottmann, S. Radunz, J. Treckmann, F. Saner, A. Paul, D. Hoyer.

    General Visceral and Transplantation Surgery, University Hospital, Essen, Germany

    Background Antiplatelet therapy is common in patients on the waiting list for kidney transplantation increasing the risk for perioperative blood loss. This study evaluates the…
  • 2017 American Transplant Congress

    Do Perioperative Blood Transfusions Influence Kidney Transplant Outcomes in the Modern Era?

    J. Lineen, J. Trac, Y. Li, O. Famure, J. Kim.

    Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada

    Background: Blood transfusions are a well-established risk factor for human leukocyte antigen sensitization in kidney transplant candidates. To date, relatively few studies have explored the…
  • 2017 American Transplant Congress

    Blood Transfusion Induced Donor Specific Antibodies Are Associated with Rejection and Graft Failure.

    S. Hassan,1 F. Regan,2,3 C. Brown,4 A. Harmer,3 N. Anderson,3 P. Brookes,5 D. Taube,1 M. Willicombe.1

    1Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; 2Haematology, Imperial College Healthcare NHS Trust, London, United Kingdom; 3NHS Blood and Transplant, London, United Kingdom; 4Histocompatibility and Immunogenetics, NHS Blood and Transplant, London, United Kingdom; 5Histocompatibility and Immunogenetics, Imperial College Healthcare NHS Trust, London, United Kingdom

    Introduction: Although it is well known that blood transfusions post-transplant are associated with the development of both HLA and donor specific antibodies [DSAs] and a…
  • 2017 American Transplant Congress

    Blood Transfusion Before Organ Transplant: Patient Sensitization and Outcomes.

    I. Cich, K. Rudser, R. Brown, H. Ibrahim, R. Thorson, J. Patil, G. Loor, M. Hertz, C. Cohn.

    Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN

    BackgroundBlood transfusions (Btf) can cause alloimmunization to HLA antigens. Antibodies to HLA (HLAb) can increase patients' calculated panel reactive assay (cPRA) and make it more…
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