2022 American Transplant Congress
Generation and Functional Characterization of Bio-Engineered Livers for Heterotopic Implantation in Porcine Model of Acute Liver Failure
*Purpose: Liver transplantation has shown to be an effective therapy for the end-stage liver diseases (ESLD). However, as donor organ shortages increase, organ engineering technology…2020 American Transplant Congress
Characterization of a Clinically Scaled Bioengineered Liver Seeded with Primary Hepatocytes and Endothelial Cells
1Miromatrix, Eden Prairie, MN, 2Mayo Clinic, Rochester, MN
*Purpose: Advancements in whole organ bioengineering have the potential to offer solutions to a chronically insufficient donor organ supply. We recently demonstrated an ability to…2017 American Transplant Congress
Liver Regeneration in Porcine Hepatectomy Model.
Department of Transplantation Surgery, Mayo Clinic, Rochester, MN
Background: Acute Liver Failure (ALF) is a serious condition. A substantial number of donor livers (10%) are used to save ALF patients. Supportive therapies such…2015 American Transplant Congress
Bioengineering Liver Allografts through Organ Scaffold Recellularization
University of Maryland School of Medicine, Baltimore.
Bioengineering livers using organ scaffolds offers an approach to increasing allograft availability for end stage liver disease. Recellularized liver scaffolds will require multiple differentiated cell…
American Transplant Congress abstracts