2022 American Transplant Congress
Microvascular Inflammation without Antibody Mediated Rejection in Renal Transplantation
Thomas E. Starzl Transplantation Institute, UPMC, Pittsburgh, PA
*Purpose: Microvascular inflammation (MVI) defined by glomerulitis (g) and peritubular capillaritis (ptc) is a hallmark of ABMR in renal transplantation. The prevalence and significance of…2022 American Transplant Congress
Immunogenicity of a Quadrivalent Human Papillomavirus Vaccine in Pediatric Kidney and Liver Transplant Recipients
*Purpose: Solid-organ transplant recipients are at increased risk of developing human papillomavirus (HPV)-related diseases. The immunogenicity of HPV vaccine for solid-organ transplant population needs further…2022 American Transplant Congress
Preliminary Data of the Safety and Immunogenicity Protocol of Vaccination for SARS-CoV 2 in Solid Organ Transplant Patients in Argentina
*Purpose: To evaluate the safety and generation rate of Ab anti spike rate in SOT patients at 28 and 90 days after completing the Covid…2022 American Transplant Congress
Antibody Response to 3-Dose SARS-CoV-2 mRNA Vaccination in Pediatric Solid Organ Transplant Recipients
*Purpose: We report the immunogenicity and safety of a third BNT162b2 vaccine in pediatric solid organ transplant recipients (pSOTRs).*Methods: Samples from pSOTRs (12-18 years) enrolled…2022 American Transplant Congress
Three Month Antibody Durability and Kinetics in Sars-cov-2 Mrna Vaccinated Heart and Lung Transplant Recipients: Differences Above the Diaphragm
1Johns Hopkins, Baltimore, MD, 2University of Wisconsin, Madison, WI
*Purpose: Heart and lung transplant (HT/LT) recipients have impaired humoral responses to SARS-CoV-2 vaccination compared to other solid organ transplant recipients (SOTRs). The purpose of…2022 American Transplant Congress
Impact of the High Baseline Anti-a/b Antibody Titer on the Clinical Outcomes in ABO-incompatible Living Donor Liver Transplantation
Surgery, Seoul National Bundang Hospital, Seongnam, Korea, Republic of
*Purpose: Recently, advances in desensitization protocol have made ABO-incompatible (ABOi) living donor liver transplantation (LDLT) feasible option in the era of organ shortage. Although, multiple…2022 American Transplant Congress
Membrane Attack Complex as a More Sensitive Tool to Evaluate Complement Activation in Kidney Transplant Recipients with Donor-Specific Antibodies
Nephrology, Hospital del Mar, Barcelona, Spain
*Purpose: Kidney transplant recipients with late HLA donor-specific antibodies (DSA) detected with single antigen beads (SAB) exhibit more frequent antibody-mediated rejection (ABMR) and graft loss.…2022 American Transplant Congress
Humoral and Cellular Immunity 6 Months After SARS-CoV-2 Infection in Solid-Organ Transplant Recipients
*Purpose: The purpose of this study was to evaluate long term humoral and cellular immunity generated following SARS-CoV-2 infection in solid organ transplant recipients (SOTR).*Methods:…2022 American Transplant Congress
Recipient Treatment with Anti-CD122 mAb Prolongs Kidney Allograft Survival During Antibody-Mediated Rejection without Impacting NK Cell Activation within the Graft
Cleveland Clinic, Cleveland, OH
*Purpose: Dysregulated donor-specific antibody (DSA) responses are induced in B6.CCR5-/- mice transplanted with complete MHC mismatched kidney allografts and are required for rejection of the…2022 American Transplant Congress
High Resolution Typing Can Improve Accuracy and Sensitivity of the Virtual Crossmatch for Sensitized Patients – A Single Center’s Experience
*Purpose: The introduction of solid phase assays has significantly enhanced our ability to execute virtual crossmatches (VXMs). However, this method is not without its shortcomings.…
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