2022 American Transplant Congress
Correlation of Non-HLA Antibodies and Biopsy-Proven Antibody-Mediated Rejection
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Non-HLA antibodies are seen in heart transplantation (HTx), but the clinical significance has not been established. In many cases, non-HLA antibodies are drawn, but…2022 American Transplant Congress
Outcomes of Highly-Sensitized, Virtual and Flow Cross-Match Negative Renal Transplant Recipients: A Retrospective Observational Study
*Purpose: Many highly-sensitized kidney transplant recipients are sensitized from prior transplants, which have been shown to limit graft survival more than pregnancy or blood transfusions.…2022 American Transplant Congress
Pre-Transplant Vaccine Induced SARS-CoV-2 Antibodies Decrease Following Induction Therapy for Kidney Transplantation
*Purpose: Kidney transplant recipients (KT) and wait-listed individuals exhibit an impaired response to vaccinations. There is currently no data on the impact of induction immunosuppression…2022 American Transplant Congress
Kinetics and Durability of a Third Dose of Sars-cov-2 Vaccination Among Solid Organ Transplant Recipients
Johns Hopkins University, Baltimore, MD
*Purpose: Understanding the dynamics of antibody response to a third dose (D3) of anti-SARS-CoV-2 vaccine in solid organ transplant recipients (SOTRs) is important to inform…2022 American Transplant Congress
Validation of Donor Specific Antibody Characteristics Associated with Deleterious Outcomes: A Single Center Study of 940 Kidney Allograft Recipients
*Purpose: A reproducibility crisis is pervasive in scientific literature. We aimed to investigate whether the DSA characteristics we previously associated with antibody mediated rejection (AMR)…2022 American Transplant Congress
Evaluation of Post-Transplant Angiotensin II Type 1 Receptor Antibodies, Donor-Derived Cell-Free DNA, and Rejection in Heart Transplant Recipients
*Purpose: There is limited evidence evaluating the relationship between angiotensin II type 1 receptor antibodies (AT1R-Abs), donor-derived cell-free DNA (dd-cfDNA), and rejection in heart transplant…2022 American Transplant Congress
De Novo Anti-Brush Border Antibody Disease in a Kidney Transplant Recipient
Ohio State University, Columbus, OH
*Purpose: Anti-brush border antibody (ABBA) disease is very rare, characterized by tubulointerstitial damage caused by autoantibodies against LDL receptor-related protein 2 (LRP2) in the proximal…2022 American Transplant Congress
How Does Anti-CD38 Antibody Treatment (Daratumumab) Impact Immunological Assessment in Solid Organ Transplantation?
*Purpose: We report the first case of Dara interference of routine pre-transplant (Tx) crossmatch (XM) repeatedly causing aberrant false positives which inadvertently delayed Tx for…2022 American Transplant Congress
Angiotensin II Type 1 Receptor Antibody in Pediatric Abdominal Organ Transplant: Survey of Clinical Practice in the United States
University Health Transplant Institute, San Antonio, TX
*Purpose: Some studies correlate Angiotensin II Type 1 Receptor (AT1R) antibodies (Ab) with the development of rejection, vascular complications, and allograft dysfunction in pediatric solid…2022 American Transplant Congress
Temporary Donor Splenic Transplant (Splenopheresis) in Simultaneous Kidney Transplant Provides a Safe Immunologic Window in Sensitized Patients
*Purpose: Deceased donor solid organ transplant in sensitized recipients with donor specific antibodies (DSA) and positive flow cytometry cross matches (FXM) are challenging due to…
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