2015 American Transplant Congress
Histologic Patterns of C4d Associated With Acute Antibody Mediated Rejection of the Lung Allograft
Pathology, UT Southwestern Medical Center, Dallas, TX.
The diagnosis of antibody mediated rejection (AMR) of the lung allograft still represents a diagnostic challenge for pathologist and transplant physicians alike. The morphologic and…2015 American Transplant Congress
Pregnancy After Renal Transplantation: Unfavorable Outcomes in Sensitized Patients
Einstein/Montefiore Transplant Center, Bronx.
Background: The objective of our study was to describe pregnancy and allograft outcomes in sensitized kidney recipients in a predominantly Hispanic and African-American population.Methods: This…2015 American Transplant Congress
Heart Transplant for Amyloid Patients in the Current Era of Bortezomib
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Both amyloid light chain (AL) amyloidosis and transthyretin-related (TTR) amyloid have been viewed with reluctance to proceed with heart transplant. AL amyloid in particular…2015 American Transplant Congress
The C1q-Binding Assays and Clinical Outcomes in Kidney Transplantation
Background: Contradictory conclusions have emerged from clinical trials when testing the predictive value of C1q-binding donor-specific HLA-antibodies (HLA-DSA). The aim of this study was to…2015 American Transplant Congress
A New Diagnostic and Pronostic Tool for Antibody Mediated Rejection in Kidney Transplantation: Intragraft Donor Specific Anti-HLA Antibodies Detection
INTRODUCTION: Antibody mediated rejection (AMR) is one of the main cause of loss of the kidney transplant. Despite the new BANFF classification, diagnostic difficulties and…2015 American Transplant Congress
Respiratory Infections Following Lung Transplantation Leads to De Novo Development of Antibodies to Both Donor HLA and Lung Associated Self-Antigens and Increases the Risk for Bronchiolitis Obliterans Syndrome
Background: It is accepted that lower respiratory tract infections (LRI) post lung transplantation (LTx) are a risk factor for the development of Bronchiolitis Obliterans Syndrome…2015 American Transplant Congress
The Value of Surveillance Testing for De Novo Donor Specific Antibodies Following Renal Transplantation
1Medicine, SUNY at Buffalo/ECMC, Buffalo, NY; 2Surgery, SUNY at Buffalo/ECMC, Buffalo, NY.
The development of de novo donor specific antibodies (dnDSA) usually leads to a reduction in renal graft survival. The deleterious influence of dnDSA is most…2015 American Transplant Congress
Toll-Like Receptor 4-Signaling Abrogates Inhibitory Effect of Calcineurin Inhibitor on B-Cells Responding to Blood Group A-Antigens
Transplant Unit, Hiroshima University, Hiroshima, Japan.
Aim: Bacterial infection following ABO-incompatible organ-transplantation is associated with refractory Ab-mediated rejection. Here, we investigated the influence of toll-like receptor (TLR)-signaling, via the binding of…2015 American Transplant Congress
Deficiency of Naturally Occurring Anti-Angiogenic Antibodies Associate With the Development of Metastatic Cancer Post Renal Transplantation and Patient Death
We assessed the presence of naturally occurring blocking antibodies to mediators of vascularisation and metastasis in Kidney Transplant Recipients (KTR) with metastatic cancer (n=11), non…2015 American Transplant Congress
The Impact of Therapy On the Inflammatory Infiltrate in Renal Allografts With Acute and Chronic Antibody Mediated Rejection
Little is known about the effect of usual treatment for acute and chronic antibody mediated rejection (aAMR and cAMR) on inflammatory cells within the allograft.…
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