2016 American Transplant Congress
Early Onset Acute Antibody Mediated Rejection (ABMR) Is More Common in Female Than in Male Recipients of a Living Unrelated Donor (LURD) Renal Transplant and Is Associated with the Presence of Preformed Donor Specific Antibodies (DSA).
1Nephrology, LUMC, Leiden, Netherlands; 2IHB, LUMC, Leiden, Netherlands.
Introduction: Women who receive a renal graft from their male spouse have a higher risk of early onset acute ABMR. The aim of this study…2016 American Transplant Congress
Optimal Integration of Kidney Exchange Programs with Antibody Reduction Therapy to Increase Successful Transplant in Difficult to Match Recipients.
Kidney paired donation (KPD) allows incompatible pairs to exchange kidneys with other incompatible pairs. However, evidence suggests there stills exist barriers to KPD utilization, especially…2016 American Transplant Congress
Monitoring of De Novo DSA Post Alemtuzumab Induction in Renal Transplant Recipients: One Year Follow Up.
Nephrology & Hypertension, Stony Brook Medicine, Stony Brook, NY.
IntroductionThe presence of de novo DSA (dnDSA) is associated with antibody mediated rejection and less optimal graft outcomes. The overall incidence of dnDSA post renal…2016 American Transplant Congress
Molecular Significance of Microvascular Inflammation and C4d Negative Transplant Glomerulopathy.
Background: Transplant glomerulopathy (TGP) is frequently found in the setting of chronic antibody mediated rejection along with microvascular inflammation (MVI) (peritubular capillaritis+glomerulitis score > 1)…2016 American Transplant Congress
Negative Impact of Anticardiolipid Antibodies on 1-Year Renal Allograft Estimated Glomerular Filtration Rate: A Cohort Study.
In kidney transplant recipients, antiphospholipid positive tests without antiphospholipid syndrome (APS) were described up to 38% of patients and seem to be associated with thrombotic…2016 American Transplant Congress
Urine IP-10 as the Biomarker for ABMR in Kidney Transplant Recipient with DGF.
Background: In the setting of DGF in kidney transplantation (KT), early acute ABMR, which needs early treatment, has to be differentiated from simple ischemic acute…2016 American Transplant Congress
Incidence and Factors Associated with De Novo DSA After BK Viremia in Renal Transplant Recipients.
Houston Methodist Hospital, Houston, TX.
Recent literature indicates an elevated rate of de novo DSA (dnDSA) following BK viremia (BKV) in renal transplant recipients (RTR). We sought to review our…2016 American Transplant Congress
Impact of Pretransplant Non-Donor-Specific HLA Immunization: Mainly Class 1 Immunization Leads to Poor Immunologic Outcome and Graft Loss.
Nephrology, Charite, Berlin, Germany.
Background Anti-HLA immunization measured as Panel Reactive Antibodies (PRA) is known to have a negative impact on patient and graft survival. The influence of pre-transplant…2016 American Transplant Congress
Exosome-Like Vesicles Released in Association with Tissue Injury Trigger Anti-LG3 Production.
Pre-transplant levels of autoantibodies to perlecan/LG3 predict poor allograft outcomes in renal transplant patients. We showed previously thatapoptotic exosome-like vesicles (ApoExo) enhance anti-LG3 production and…2016 American Transplant Congress
Glomerular Capillary C4d Staining without Evidence of Rejection Is Associated with Worse Graft Function in ABO-Incompatible Kidney Transplantation.
Objectives: C4d staining in the peritubular capillaries (C4d-PTC) is often observed without evidence of rejection in ABO-incompatible kidney transplantation (ABOI-KTx), and this phenomenon is generally…
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