ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Allocation"

  • 2017 American Transplant Congress

    A Novel Computational HLA Matching Algorithm for Improving Donor-Recipient Histocompatibility and Graft Outcomes After Kidney Transplantation.

    V. Kosmoliaptsis,1 D. Mallon,1 S. Fuggle,2 R. Johnson,2 C. Watson,1 J. Bradley,1 C. Taylor.1

    1Department of Surgery, University of Cambridge, Cambridge, United Kingdom; 2NHS Blood and Transplant, Bristol, United Kingdom

    Introduction: Human Leukocyte Antigen (HLA) matching is a central objective of kidney allocation policies, but current assessment of histocompatibility is inadequate. Building on our previous…
  • 2017 American Transplant Congress

    Is Lung Allocation Score Associated with Waitlist and Post-Transplant Survival?

    H. Maredia, M. Bowring, A. Massie, S. Oyetunji, C. Merlo, R. Higgins, D. Segev, E. Bush.

    JHU, Baltimore

    The lung allocation score (LAS) prioritizes patients based on predicted one-year waitlist and post-transplant mortality. However, for a given diagnosis, it is unclear whether LAS…
  • 2017 American Transplant Congress

    A Surge in Liver Donors After Years of Decline, Is This the Tip of the Iceberg?

    A. Rana,1 M. Goss,1 J. Rees,2 M. Kueht,1 J. Vierling,1 A. Mindikoglu,1 K. Halazun,3 N. Sussman,1 B. Kaplan,4 P. Wood,5 N. Galvan,1 R. Cotton,1 C. O'Mahony,1 J. Goss.1

    1Abdominal Transplantation, Baylor College of Medicine, Houston; 2Southwest Transplant Alliance Organ Procurement Organization, Dallas; 3Surgery, Weill Cornell Medical Center, New York; 4Nephrology, Mayo Clinic, Phoenix; 5LifeGift Organ Procurement Organization, Houston

    The number of liver donors has steadily declined since 2006, despite numerous efforts to increase donation. Then in 2013 to the current projected numbers for…
  • 2017 American Transplant Congress

    Unintended Consequence of the New Kidney Allocation System – Disproportionate Allocation of High Quality Kidneys to Highly Sensitized Recipients.

    B. Murthy, N. Galvan, J. Moffett, C. O'Mahony, J. Goss, A. Rana.

    Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX

    Purpose: We hypothesize that improving access to highly sensitized candidates in new KAS would compromise the prime objective of matching the best kidney allografts and…
  • 2017 American Transplant Congress

    Community Health, Center Proximity, and Liver Transplant Waitlist Mortality.

    R. Lynch,1 K. Ross,1 D. Goldberg,2 R. Patzer.1

    1Surgery, Emory University, Atlanta, GA; 2Medicine, University of Pennsylvania, Philadelphia, PA

    Background: While regional organ availability is frequently discussed in allocation policy, the impact of community-level factors and access to a transplant center on waitlist mortality…
  • 2017 American Transplant Congress

    Kidney Allograft Offers: Predictors of Turndown and the Relationship of Organ Acceptance Sequence to Kidney Allograft Survival.

    J. Cohen,1,2 J. Shults,2 D. Goldberg,2,3 D. Sawinski,1 P. Abt,4 P. Reese.1,2

    1Renal Division, University of Pennsylvania, Philadelphia, PA; 2Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA; 3Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA; 4Transplant Surgery, University of Pennsylvania, Philadelphia, PA

    Background: There is growing interest in understanding patterns of organ acceptance and reducing organ discard. Little is known about how donor factors, holidays, and location…
  • 2017 American Transplant Congress

    Lung Transplant Recipient Travel Distance to Transplant Center Does Not Impact Survival.

    W. Tsuang,1 S. Lin,2 J. Schold,2 M. Valapour.1

    1Respiratory Institute, Cleveland Clinic, Cleveland, OH; 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH

    Purpose: We examined if the geographic distance recipients travel for lung transplant care impacts posttransplant survival at our center.Methods: Retrospective single center cohort study of…
  • 2017 American Transplant Congress

    Exception Scores for Patients on the Liver Waiting List.

    T. Weaver,1 D. Schladt,1 M. Skeans,1 J. Pyke,1 J. Zeglin,1 S. Leppke,1 A. Israni,1,2 B. Kasiske,1,2 W. Kim,3 J. Lake.4

    1Scientific Registry of Transplant Recipients, Minneapolis, MN; 2Hennepin County Medical Center, Minneapolis, MN; 3Stanford University, Stanford, CA; 4University of Minnesota, Minneapolis, MN

    Liver waitlist candidates are prioritized for allocation using model for end-stage liver disease (MELD) scores, and some patients receive higher MELD scores through exception. The…
  • 2017 American Transplant Congress

    Geographic Disparity in Kidney Transplantation After KAS.

    S. Zhou,1 A. Massie,1 X. Luo,1 E. Chow,1 S. Bae,1 S. Gentry,2 S. Gustafson,3 A. Wey,3 B. Thompson,3 N. Salkowski,3 J. Snyder,3 D. Segev.1

    1JHU, Baltimore; 2USNA, Annapolis; 3CDRG, Minneapolis

    The Kidney Allocation System (KAS), implemented in 12/2014, increased regional and national sharing of kidneys. Ideally, broader sharing would also reduce some of the stark…
  • 2017 American Transplant Congress

    Donor Recipient Matching Based on HLA Epitopes Improves Outcome in Kidney Transplant Recipients.

    O. Staeck,1 M. Niemann,3 F. Halleck,1 D. Khadzhynov,1 C. Schönemann,2 P. Reinke,1 E. Spierings,4 K. Budde,1 N. Lachmann.2

    1Nephrology, Charité Universitaetsmedizin, Berlin, Germany; 2HLA Laboratory, Charité Universitaetsmedizin, Berlin, Germany; 3PIRCHE, Berlin, Germany; 4Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands

    Background: HLA mismatches of the donor and recipient causing de novo donor-specific HLA antibodies (dnDSA) are a risk factor for immunologic complications and poor graft…
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