Articles tagged "Allocation"

2018 American Transplant Congress
Cumulative United States Experience in Domino Liver Transplants
K. Barrera, S. Sharma, A. Gruessner, R. Gruessner.
Surgery, State University of New York, Downstate, Brooklyn, CA.
Background/Purpose: The ongoing shortage of livers in the setting of growing waiting lists remains a challenge in transplantation. First introduced in 1995, sequential or domino…
2018 American Transplant Congress
Informatics Tools for Mapping Molecular HLA Typing Data to UNOS Antigen Equivalencies
N. Kaur,¹ E. Kransdorf,² M. Pando,³ M. Maiers,⁴ L. Gragert.^1,4
¹Tulane University School of Medicine, New Orleans; ²Cedars-Sinai Heart Institute, Los Angeles; ³Baylor Scott and White, Temple; ⁴National Marrow Donor Program / Be The Match, Minneapolis.
Introduction:Molecular HLA typing must be converted to antigen equivalencies for entry into the UNOS database, UNet. Maintaining an up-to-date mapping table for this purpose has…
2018 American Transplant Congress
Reassessment of Virtual Crossmatch: The Clinical Meaning of Cell-Based Actual Crossmatch for Kidney Transplantation
B. Peng,^1,2 M. Yu,^1,2 Q. Zhuang,^1,2 H. Liu,^1,2 L. Zhu,^1,2 Y. Liu,^1,2 K. Cheng,^1,2 Y. Ming.^1,2
¹Transplantation Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China; ²Engineering & Technology Research Center for Transplantation Medicine, National Ministry of Health, Changsha, Hunan, China.
Background: Due to the high sensitivity and specificity of Luminex technique, the Luminex single antigen beads (LSAB) assays are widely used in detecting the HLA…
2018 American Transplant Congress
Accepting a DCD Liver May Improve Patient Survival Compared to Waiting for a Non-DCD Liver
A. Wey,¹ N. Salkowski,¹ J. Lake,² W. Kim,³ B. Kasiske,¹ A. Israni,¹ J. Snyder.¹
¹Scientific Registry of Transplant Recipients, Minneapolis; ²Univ of Minnesota, Minneapolis; ³Stanford University, Palo Alto.
Only ~50% of liver candidates undergo deceased donor transplant; 17% die on the waiting list and 20% are removed from the list as too sick…
2018 American Transplant Congress
Improving Prognostication amongst Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma: An International, 16-Center Study to Validate and Recalibrate HALTHCC
D. Firl,¹ K. Sasaki,¹ S. Kimura,² W. Dumronggittigule,³ A. Gorgen,⁴ J. Lerut,⁵ M. Rossi,⁶ U. Cillo,⁷ A. Viveiros,⁸ E. Tsochatzis,⁹ G. Otto,¹⁰ G. Ettorre,¹¹ G. Tisone,¹² M. Vivarelli,¹³ S. Agnes,¹⁴ J. Markmann,² T. Ikegami,¹⁵ T. Kaido,¹⁶ G. Sapisochin,⁴ V. Agopian,³ Q. Lai,^5,6 F. Aucejo.¹
¹CCF, Cleveland; ²MGH, Boston; ³UCLA, LA; ⁴UHN, Toronto, Canada; ⁵SLH, Louvain, Belgium; ⁶UH, Rome, Italy; ⁷UP, Padua, Italy; ⁸MUI, Innsbruck, Austria; ⁹UCL, London, United Kingdom; ¹⁰UM, Mainz, Germany; ¹¹SCH, Rome, Italy; ¹²TVU, Rome, Italy; ¹³AOU, Torrette Ancona, Italy; ¹⁴AGH, Rome, Italy; ¹⁵KU, Kyoto, Japan; ¹⁶KU, Kyushu, Japan.
Objective: Prognosticating outcomes in liver transplant (LT) for hepatocellular carcinoma (HCC) continues to challenge the field. Whereas adoption of the binary Milan Criteria (MC) generalized…
2018 American Transplant Congress
Liver Allocation: One OPO's Experience with Expedited versus Non-Expedited Placement
C. Muse, R. Squires, C. Trahan, J. Whaley, J. Orlowski.
LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK.
Background: One organ procurement organization (OPO) sought to study expedited versus non-expedited livers recovered/transplanted after local/regional centers declined. The OPO sought to determine relative recipient…
2018 American Transplant Congress
A Calculated Panel Reactive Antibody (CPRA) Calculator Supporting Both Allele-Level and Antigen-Level HLA Specificities
L. Gragert,^1,2 E. Kransdorf,³ N. Kaur,¹ M. Maiers,² J. Kobashigawa,³ M. Pando.⁴
¹Tulane University School of Medicine, New Orleans; ²National Marrow Donor Program / Be The Match, Minneapolis; ³Cedars-Sinai Heart Institute, Los Angeles; ⁴Baylor Scott and White, Temple.
Introduction:The number of HLA alleles represented on Luminex assays has increased over time, allowing for improved characterization of anti-HLA antibody specificity. Calculated Panel Reactive Antibody…
2018 American Transplant Congress
Exploring the Viability of Kidneys Discarded in the US: A Comparison of Kidney Utilization Patterns and Outcomes in the US and France
O. Aubert, P. Reese, M. Raynaud, D. Viglietti, C. Loheac, N. Kamar, M. Delahousse, C. Legendre, D. Glotz, C. Lefaucheur, A. Loupy.
Paris Translational Center for Organ Transplantation, Paris, France.
Approximately 2,000 donated kidneys are discarded in the US each year. Some transplant leaders have questioned the viability of these lost organs, while others suggest…
2018 American Transplant Congress
Estimation of Mortality on the Wait List
S. Asrani, L. Jennings, J. Trotter, G. Klintmalm.
Baylor University Medical Center, Dallas, TX.
Background: Since the introduction of MELD and MELDNa, the waitlist population has changed. Further, serum creatinine is a poor surrogate of renal dysfunction in patients…
2018 American Transplant Congress
Positive Relationship between Transplant Center Volume and Utilization of Hard to Place Liver Allografts after Late Declines
J. Knox,¹ H. Braun,¹ S. Syeed,¹ K. Halazun,² G. Roll.¹
¹Department of Transplant Surgery, UCSF, San Francisco, CA; ²Weill Cornell Medical Center, New York, NY.
Given ongoing waitlist mortality and the high rates of liver discard in the US we wanted to investigate late declines (LD), and very late declines…