2015 American Transplant Congress
Etiology, Incidence and Outcomes of the Highly Sensitized Kidney Transplant Patient
University of Wisconsin, Madison, WI.
Background: Sensitization to HLA antigens is a major barrier to kidney transplantation. We sought to determine the etiology, incidence and outcomes of kidney transplants performed…2015 American Transplant Congress
Detection of Donor Specific HLA-Ab (DSA) Against Native HLA Molecules Expressed On Donor Cell Surface to Eliminate False Positive DSA in Luminex Single Antigen Beads (LMX-SAB)
Pathology, Stanford University, Palo Alto, CA.
Introduction:The LMX-SAB has been extensively used for DSA virtual crossmatch (VXM) to predict actual crossmatch (AXM). The extreme pH and harsh chemical reaction conditions used…2015 American Transplant Congress
Antibody-Induced Platelet Activation Increases Allograft Hyaluronan Fragmentation
Antibodies to MHC class I antigens have been shown to activate endothelial cells to release von Willebrand factor (vWf) and P-selectin from storage granules. These…2015 American Transplant Congress
Is Electron Microscopy Adding a Diagnostic Advantage in the Evaluation of Renal Allograft Biopsies for Antibody Mediated Rejection (AMR)?
Pathology and Medicine, University of Maryland School of Medicine, Baltimore, MD.
Some electron microscopy (EM) findings have been consistently associated with antibody mediated microvascular injury; however, no large studies have been performed examining the concrete advantage…2015 American Transplant Congress
Controlling Alloreactive B Cell Responses in Sensitized Recipients With CTLA-4Ig
Sensitized recipients are defined by the presence of pre-transplant donor-specific antibodies and have significantly poorer graft outcomes compared to unsensitized recipients despite efforts to desensitize.…2015 American Transplant Congress
Role of CMV, BKV, and Immunosupression Non-Adherence in Early and Late De Novo Donor Specific Anti-HLA Antibody Development and Outcomes
This analysis aims to identify appropriate de novo DSA (dnDSA) screening points and delineate the post-transplant (txp) scenarios preceding dnDSA development to aid in clinical…2015 American Transplant Congress
Alterations in Peripheral Blood B Cell Subpopulations in Kidney Transplant Recipients With DSA
Peripheral blood B cell subpopulations were assessed over time (1, 3, 6, 9, and 12 months) in living donor kidney transplant recipients undergoing thymoglobulin (n…2015 American Transplant Congress
Early Clinical Indicators of Long Term Survival and Allograft Loss Following De Novo DSA. A 15-Year Longitudinal Study
Improvement in outcomes in renal transplant patients with de novo donor specific anti-HLA antibodies (dnDSA) is needed. This analysis aims to identify surrogate endpoints following…2015 American Transplant Congress
The Forgotten Cell: Renal Fibroblasts Are Activated By Anti-MHC Class I Antibody
Medicine and Surgery, University of Alabama at Birmingham, Birmingham, AL.
Chronic antibody-mediated (CAMR) rejection remains a major obstacle in the long term survival of kidney transplants, and is associated in part with interstitial fibrosis (IF)…2015 American Transplant Congress
Chronic Active Antibody Mediated Rejection (cABMR): Treatment, Outcomes and Predictors of Graft Loss in a Large Case Series
1University of Wisconsin, Madison, WI; 2University of Michigan, Ann Arbor, MI.
Background: CABMR is a barrier to long-term kidney allograft survival. There is little information on the treatment and outcomes of kidney transplant recipients with cABMR.Methods:…
- « Previous Page
- 1
- …
- 33
- 34
- 35
- 36
- 37
- …
- 40
- Next Page »