Articles tagged "Alcohol"

2021 American Transplant Congress
Implementation of an Alcohol Screening Program Identifies Active Pre-transplant Drinking and Allows Engagement in Chemical Dependency Treatment
N. Lim¹, T. Leventhal¹, M. Thomson¹, M. Hassan¹, J. Thompson¹, S. Chinnakotla², V. Kirchner², T. Pruett², R. Kandaswamy², V. Humphreville², A. Adams², J. Lake¹
¹Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, ²Division of Transplantation, University of Minnesota, Minneapolis, MN
*Purpose: Alcohol (ETOH) is an important cause of cirrhosis in the US today. Screening patients for ETOH use prior to LT is important to identify…
2021 American Transplant Congress
Serum Phosphatidylethanol is Superior to Urine Ethyl Glucuronide for Detection of Alcohol Use in Pre-transplant Patients
N. Lim¹, T. Leventhal¹, M. Thomson¹, M. Hassan¹, J. Thompson¹, S. Chinnakotla², V. Kirchner², T. Pruett², R. Kandaswamy², V. Humphreville², A. Adams², J. Lake¹
¹Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, ²Division of Transplantation, University of Minnesota, Minneapolis, MN
*Purpose: More patients are presenting for liver transplant (LT) evaluation for alcohol-related liver disease (ALD). Detection of ETOH use has significant implications for patients undergoing…
2021 American Transplant Congress
A Shift in Paradigm: Phosphatidylethanol Testing to Monitor for and Address Alcohol Recidivism Following Liver Transplantation
F. M. Nimri¹, S. Naffouj¹, F. Askar¹, A. Singh², H. Gonzalez², S. Jafri²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI, ²Gastroenterology, Henry Ford Hospital, Detroit, MI
*Purpose: Phosphatidylethanol (PEth) is a phospholipid that forms in the presence of ethanol with a long half-life compared to other alcohol detection tests. PEth testing…
2021 American Transplant Congress
Recent Trends and Outcomes of Liver Transplantation for Non-alcoholic Steatohepatitis versus Alcohol Liver Disease in the United States: Obesity Might be Protective
K. Okumura, I. Lee, H. Sogawa, G. Veillette, D. John, T. Diflo, R. Bodin, D. Wolf, S. Nishida
Surgery, Westchester Medical Center/New York Medical College, Valhalla, NY
*Purpose: Nonalcoholic steatohepatitis (NASH) and alcohol liver disease (ALD) are rapidly growing indications for liver transplantation (LT). The recent trends and outcomes in NASH and…
2020 American Transplant Congress
Effects of Donor Heavy Alcohol Use on Post-Heart Transplant Outcomes: Time to Abstain?
J. Patel, M. Kittleson, D. Chang, E. Kransdorf, D. Geft, A. Shen, K. Nishihara, G. Jamero, L. Czer, F. Esmailian, J. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Donors with a history of heavy alcohol use have been suspected to possibly harbor a subclinical alcoholic cardiomyopathy with limited cardiac reserve. This problem…
2020 American Transplant Congress
Exploring Psychosocial Factors and Disparity in Liver Transplant
K. Schmidt
Dept. of Psychiatry & Behavioral Sciences, Emory University, Atlanta, GA
*Purpose: Trends in liver transplant (LT) have shifted, and increasingly, individuals with alcohol liver disease (ALD) are receiving LT without 6-months of sobriety (Lee &…
2020 American Transplant Congress
Duration of Pre-Transplant Abstinence Does Not Predict Severe Relapses of Alcohol Abuse in High-Risk Alcoholic Liver Transplant Recipients
W. H. Kitchens
Emory Transplant Center, Atlanta, GA
*Purpose: The traditional requirement of >6 months pre-transplant sobriety for liver transplant recipients has been challenged by emerging literature, but risk factors for post-transplant recidivism…
2020 American Transplant Congress
De Novo Malignancy after Liver Transplantation for Alcoholic Cirrhosis: Incidence and Outcomes
M. M. Pascale, E. Nure, G. Bianco, F. Frongillo, S. Agnes
Transplant Unit, Fondazione "Policlinico A. Gemelli" UCSC - Rome, Roma, Italy
*Purpose: De novo malignancy, frequent liver transplant (LT) complication, is one of the long-term major causes of mortality. Risk factors are related to immunosuppressive status,…
2020 American Transplant Congress
Association between Alcoholic Liver Disease and Alcohol Tax
S. Melo¹, A. Ermekbaeva², J. Buggs³, E. Rogers³, A. Kumar⁴, N. Kemmer⁵
¹School of Medicine, Indiana University, Indianapolis, IN, ²Honors College, University of South Florida, Tampa, FL, ³Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁴Morsani College of Medicine, University of South Florida, Tampa, FL, ⁵Transplant Hepatology, Tampa General Hospital, Tampa, FL
*Purpose: The incidence of Alcoholic Liver Disease (ALD) has increased, causing ALD to become a primary indication for liver transplantation in the United States. We…
2020 American Transplant Congress
The Pro-Inflammatory Profile of Alcoholic Patients Increases Risk for Ischemia-Reperfusion Injury During Orthotopic Liver Transplantation
A. Q. Terry¹, R. A. Sosa¹, M. Rossetti¹, F. Li¹, J. Nevarez-Mejia¹, B. V. Naini¹, F. M. Kaldas², V. M. Groysberg¹, S. M. Younan², R. W. Busuttil², D. W. Gjertson¹, J. W. Kupiec-Weglinski³, E. F. Reed¹
¹Department of Pathology and Laboratory Medicine, UCLA, Los Angeles, CA, ²Department of Surgery, UCLA, Los Angeles, CA, ³Departments of Pathology and Laboratory Medicine and Surgery, UCLA, Los Angeles, CA
*Purpose: Ischemia-reperfusion injury (IRI) elicits cellular damage which triggers a pro-inflammatory immune response that can lower allograft survival in orthotopic liver transplant (OLT) patients. In…