Articles tagged "Alcohol"

2021 American Transplant Congress
Implementation of an Alcohol Screening Program Identifies Active Pre-transplant Drinking and Allows Engagement in Chemical Dependency Treatment
N. Lim¹, T. Leventhal¹, M. Thomson¹, M. Hassan¹, J. Thompson¹, S. Chinnakotla², V. Kirchner², T. Pruett², R. Kandaswamy², V. Humphreville², A. Adams², J. Lake¹
¹Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, ²Division of Transplantation, University of Minnesota, Minneapolis, MN
*Purpose: Alcohol (ETOH) is an important cause of cirrhosis in the US today. Screening patients for ETOH use prior to LT is important to identify…
2021 American Transplant Congress
Serum Phosphatidylethanol is Superior to Urine Ethyl Glucuronide for Detection of Alcohol Use in Pre-transplant Patients
N. Lim¹, T. Leventhal¹, M. Thomson¹, M. Hassan¹, J. Thompson¹, S. Chinnakotla², V. Kirchner², T. Pruett², R. Kandaswamy², V. Humphreville², A. Adams², J. Lake¹
¹Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, ²Division of Transplantation, University of Minnesota, Minneapolis, MN
*Purpose: More patients are presenting for liver transplant (LT) evaluation for alcohol-related liver disease (ALD). Detection of ETOH use has significant implications for patients undergoing…
2021 American Transplant Congress
A Shift in Paradigm: Phosphatidylethanol Testing to Monitor for and Address Alcohol Recidivism Following Liver Transplantation
F. M. Nimri¹, S. Naffouj¹, F. Askar¹, A. Singh², H. Gonzalez², S. Jafri²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI, ²Gastroenterology, Henry Ford Hospital, Detroit, MI
*Purpose: Phosphatidylethanol (PEth) is a phospholipid that forms in the presence of ethanol with a long half-life compared to other alcohol detection tests. PEth testing…
2021 American Transplant Congress
Recent Trends and Outcomes of Liver Transplantation for Non-alcoholic Steatohepatitis versus Alcohol Liver Disease in the United States: Obesity Might be Protective
K. Okumura, I. Lee, H. Sogawa, G. Veillette, D. John, T. Diflo, R. Bodin, D. Wolf, S. Nishida
Surgery, Westchester Medical Center/New York Medical College, Valhalla, NY
*Purpose: Nonalcoholic steatohepatitis (NASH) and alcohol liver disease (ALD) are rapidly growing indications for liver transplantation (LT). The recent trends and outcomes in NASH and…
2020 American Transplant Congress
Association between Alcoholic Liver Disease and Alcohol Tax
S. Melo¹, A. Ermekbaeva², J. Buggs³, E. Rogers³, A. Kumar⁴, N. Kemmer⁵
¹School of Medicine, Indiana University, Indianapolis, IN, ²Honors College, University of South Florida, Tampa, FL, ³Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁴Morsani College of Medicine, University of South Florida, Tampa, FL, ⁵Transplant Hepatology, Tampa General Hospital, Tampa, FL
*Purpose: The incidence of Alcoholic Liver Disease (ALD) has increased, causing ALD to become a primary indication for liver transplantation in the United States. We…
2020 American Transplant Congress
The Pro-Inflammatory Profile of Alcoholic Patients Increases Risk for Ischemia-Reperfusion Injury During Orthotopic Liver Transplantation
A. Q. Terry¹, R. A. Sosa¹, M. Rossetti¹, F. Li¹, J. Nevarez-Mejia¹, B. V. Naini¹, F. M. Kaldas², V. M. Groysberg¹, S. M. Younan², R. W. Busuttil², D. W. Gjertson¹, J. W. Kupiec-Weglinski³, E. F. Reed¹
¹Department of Pathology and Laboratory Medicine, UCLA, Los Angeles, CA, ²Department of Surgery, UCLA, Los Angeles, CA, ³Departments of Pathology and Laboratory Medicine and Surgery, UCLA, Los Angeles, CA
*Purpose: Ischemia-reperfusion injury (IRI) elicits cellular damage which triggers a pro-inflammatory immune response that can lower allograft survival in orthotopic liver transplant (OLT) patients. In…
2020 American Transplant Congress
Characterizing the Waitlist Candidate Who Was Bypassed by the Successfully Transplanted Candidate with Alcoholic Hepatitis
J. Ge¹, C. L. Berg², F. Y. Yao¹, J. P. Roberts³, J. C. Lai¹
¹Medicine - Gastroenterology, University of California, San Francisco, San Francisco, CA, ²Duke University, Durham, NC, ³Surgery, University of California, San Francisco, San Francisco, CA
*Purpose: Early liver transplantation (LT) for acute alcoholic hepatitis (AH) has increased dramatically in the US since 2016. Due to high MELD-Na scores, AH candidates…
2020 American Transplant Congress
Increasing Prevalence and Diversity: Alcoholic Liver Disease in Liver Transplant Candidates
M. Joshi, E. L. Godfrey, J. A. Goss, A. Rana
Baylor College of Medicine, Houston, TX
*Purpose: Increasing global alcohol use translates to a marked growth in alcoholic liver disease (ALD). ALD patients comprise a larger proportion of listings for liver…
2020 American Transplant Congress
Perioperative Opioid Avoidance in Liver Transplant Recipients: Significant Reduction in Opioid Use Through a Multidiscplinary, Multimodal Approach
H. Kutzler, R. Gannon, W. Nolan, L. Meisterling, M. Cech, D. Gleason, J. Uzl, C. Rochon, B. Maneckshana, O. Serrano, J. Riley, D. O'Sullivan, E. Urtasun-Sotil, M. Einstein, P. Sheiner
Hartford Hospital, Hartford, CT
*Purpose: Given the association between substance use disorder and risk of post-surgical opioid use disorder, we developed an opioid avoidance pathway (OAP) in adult liver…
2020 American Transplant Congress
Results of a Prospective Pilot Program for Transplantation of Patients with Alcohol-Related Liver Disease and Less Than 6 Months Abstinence
J. Quance, L. Carrique, I. Sales, L. Lilly, M. Bhat, Z. Galvin, A. Tan, S. Abbey, J. Lynch, N. Selzner
Multiorgan Transplant Institute, University of Toronto, Toronto, ON, Canada
*Purpose: In Canada, 6 months of abstinence for those with alcohol-associated liver disease (ALD) is typically required prior to being listed for liver transplantation (LT).This…