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Articles tagged "African-American"

  • 2018 American Transplant Congress

    Time within Therapeutic Range: A Comparison of Three Tacrolimus Formulations in Renal Transplant Recipients

    K. Khalil, P. West-Thielke, A. Lichvar, E. Benedetti, S. Patel.

    University of Illinois Hospital & Health Sciences System, Chicago, IL.

    Purpose: To compare three formulations of tacrolimus (TAC) and assess differences in time within therapeutic range (TTR) and variability in levels.Methods: Renal transplant recipients from…
  • 2018 American Transplant Congress

    Kidney Transplantation in ESKD Patients with a History of Sickle Cell Disease/Trait

    A. Lee, G. Malat, M. Harhay, L. Levin, G. Xiao, S. Guy, D. Reich, K. Ranganna.

    Department of Medicine, Division of Nephrology & Hypertension, Drexel University College of Medicine, Philadelphia, PA.

    Introduction:Kidney transplantation in Sickle Cell Disease patients is fraught with complications, including increased risk of infection and thrombosis. We present long term outcomes of patients…
  • 2018 American Transplant Congress

    Evaluation of Tacrolimus Extended-Release in African American Renal Transplant Recipients

    T. Sparkes, B. Ravichandran, C. Williams, B. Thomas, B. Masters.

    University of Maryland, Baltimore.

    Purpose: Limited data exists to guide appropriate dosing strategies for novel tacrolimus formulations, such as tacrolimus XL (Astagraf XL). This is especially true in the…
  • 2018 American Transplant Congress

    Racial Differences in Patient-Perceived Barriers to Starting the Kidney Transplant Evaluation

    R. Hamoda, L. McPherson, K. Lipford, J. Gander, S. Pastan, R. Patzer.

    Emory University, Atlanta, GA.

    Overview: Racial disparities in access to kidney transplantation persist along multiple transplant steps, including start of the transplant evaluation. No studies have identified barriers that…
  • 2018 American Transplant Congress

    Target Tacrolimus Troughs and CYP3A5 Polymorphisms Do Not Predict Therapeutic Drug Exposure in African American and Caucasian Renal Transplant Recipients

    K. Tornatore,1,4 K. Attwood,2 D. Brazeau,3 S. Chang,4 R. Venuto.4

    1Pharmacy, School of Pharmacy, University at Buffalo(UB), Buffalo; 2Biostatistics, RPCI, Buffalo; 3Pharmaceutical Sciences, University of New England, Portland; 4Nephrology, UB School of Medicine, Buffalo.

    Background: African American(AA) renal transplant recipients(RTR) require larger tacrolimus(TAC) doses to achieve similar troughs to Caucasians which may be due to CYP3A5 polymorphisms. TAC pharmacokinetics…
  • 2018 American Transplant Congress

    Racial Disparities in Post-Liver Transplant Survival before and after Share 35 Implementation

    K. Ross,1 R. Lynch,2 R. Patzer.1,2

    1Department of Epidemiology, Rollins School of Public Health, Atlanta, GA; 2Emory Transplant Center, Atlanta, GA.

    Background: The Share 35 policy was intended to improve equity in access to liver transplantation by broadening regional sharing of livers for the sickest patients…
  • 2018 American Transplant Congress

    Attitudes of African Canadian Patients with End Stage Kidney Disease toward Living Donor Kidney Transplantation

    V. Gupta, C. Richardson, D. Belenko, N. Singh, A. Xu, P. Thiagalingam, D. Wong, H. Ford, M. Novak, I. Mucsi.

    University Health Network, Toronto, ON, Canada.

    Background:African Canadian patients with end stage kidney disease (ESKD) are less likely to receive a living donor kidney transplant (LDKT) compared to Caucasian Canadians. We…
  • 2017 American Transplant Congress

    Neighborhood Poverty and Racial/Ethnic Disparities in Access to Live Donor Kidney Transplantation in the US.

    T. Purnell, X. Luo, D. Crews, S. Bae, L. Kucirka, L. Cooper, D. Segev.

    Johns Hopkins University, Baltimore

    Black transplant candidates have substantially lower rates of live donor kidney transplantation (LDKT) than their White counterparts. We hypothesized that neighborhood poverty might play a…
  • 2017 American Transplant Congress

    Current Practice and Ethical Dimensions of Implementing APOL1 Testing into Living Donor Evaluation: A National Survey.

    E. Gordon,1 C. Wicklund,1 R. Sharp,2 J. Lee,1 C. Johnson,1 J. Friedewald.1

    1Northwestern University, Chicago; 2Mayo Clinic, Rochester

    BackgroundAfrican American (AA) live kidney donors (LKDs) have an even greater risk of kidney failure than European American live donors. Apolipoprotein 1 (APOL1) gene variants…
  • 2017 American Transplant Congress

    Medical Mistrust, Perceived Racism, and Experiences of Medical Discrimination Among Transplant Patients.

    R. Hamoda, K. Lipford, L. McPherson, J. Gander, R. Patzer.

    Emory University, Atlanta, GA

    Background: Racial disparities in access to transplantation are well documented, but little is known about how transplant patients' distrust of the healthcare system, perceived medical…
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