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Articles tagged "African-American"

  • 2018 American Transplant Congress

    A Theoretical Framework to Explain Factors That Impact Completion of the Medical Evaluation Process for African American (AA) End-Stage Renal Disease (ESRD) Patient

    C. Nonterah,1 H. Gardiner,2 D. Vavra.1

    1Psychology, University of Richmond, Richmond, VA; 2Department of Social and Behavioral Sciences, Temple University, Philadelphia, PA.

    Black/African Americans (B/AA) are less likely to seek kidney transplantation or complete the pre-transplant medical evaluation despite higher prevalence rates of end-stage renal disease (ESRD).…
  • 2018 American Transplant Congress

    Investigation of Lower Treatment Failure Rate Seen among Black Kidney Recipients on LCP-Tacrolimus vs. IR-Tacrolimus: Subgroup Analyses of Two Phase 3 Trials

    T. Sparkes,1 B. Masters,1 C. Staino,2 S. Patel,2 M. Cooper.3

    1University of Maryland, Baltimore, MD; 2Veloxis, Cary, NC; 3Medstar Georgetown Transplant Institute, Washington, DC.

    Black kidney transplant recipients are recognized as high risk for inferior allograft survival due to immunologic and non-immunologic factors. Pooled data from 2 Phase 3…
  • 2018 American Transplant Congress

    Is BMI > 35 a Barrier to Kidney Transplantation?

    D. Walczak, E. Benedetti, C. Ryan.

    Organ Transplant, University of Illinois, Chicago, IL.

    Background:Although lower rates of patient and graft survival are reported for kidney transplant recipients with BMI > 35, kidney transplant in this group provides a…
  • 2018 American Transplant Congress

    The Impact of Early versus Late Clinical Outcomes on Disparities in African-American Kidney Transplant Recipients

    D. Taber, J. Fleming, Z. Su, P. Mauldin, J. McGillicuddy, S. Nadig, V. Rohan, P. Baliga, D. Dubay.

    MUSC, Charleston, SC.

    Background: It is important to better understand the impact of early and late clinical events on disparities in African-American (AA) kidney transplant (KTX), which will…
  • 2018 American Transplant Congress

    Validation of Genetic Variants Identified in GWAS for Tacrolimus Troughs

    P. Jacobson,1 D. Schladt,2 W. Guan,3 J. van Setten,6 R. Remmel,4 B. Wu,3 C. Dorr,5 B. Keating,7 D. Ikle,9 R. Mannon,10 A. Matas,8 A. Israni,5 W. Oetting.1

    1Experimental and Clinical Pharmacology, Univ of MN, Minneapolis, MN; 2Chronic Disease Research Group, Minneapolis Medical Research Foundation, Hennepin County Medical Center, Minneapolis, MN; 3Division of Biostatistics, Univ of MN, Minneapolis, MN; 4Medicinal Chemistry, Univ of MN, Minneapolis, MN; 5Medicine, Hennepin County Medical Center, Minneapolis, MN; 6Cardiology, University Medical Center Utrecht, Utrecht, Netherlands; 7Surgery, Univ of Pennsylvania, Philadelphia, PA; 8Surgery, Univ of MN, Minneapolis, MN; 9Rho Inc, Chapel Hill, NC; 10Department of Medicine and Surgery, Univ of Alabama, Birmingham, AL.

    Purpose: Tacrolimus (TAC) is a substrate for CYP3A4/5 enzymes. It is well-known that variants in these genes are associated with variability in TAC trough concentrations.…
  • 2018 American Transplant Congress

    Non-Medical Factors Predict Receipt and Type of Kidney Transplant in Veterans

    K. Kendall, X. Li, C.-C. Chang, J. Pleis, E. Croswell, M. Dew, G. Switzer, A. Langone, A. Mittal-Henkle, S. Saha, M. Ramkumar, J. Adams-Flohr, C. Thomas, L. Myaskovsky.

    VA Kidney Transplant Centers: IA, OR, PA, TN, Iowa City, Portland, Pittsburgh, Nashville.

    Background: African Americans, Hispanic Americans and other minorities have a higher incidence of end-stage kidney disease but lower rates of both deceased and living donor…
  • 2018 American Transplant Congress

    Does One Size Fit All? Implementing a Protocolized Ambulatory Tacrolimus Dosing Strategy in a Predominantly African American Renal Transplant Population

    L. Gylten, C. Mardis, D. Taber, H. Meadows, C. Perez, Z. Elmaasarani, J. Fleming, N. Patel, P. Baliga, V. Rao, V. Rohan, N. Pilch.

    Medical University of South Carolina, Charleston, SC.

    Introduction: African American (AA) KTx recipients have significant tacrolimus (FK) inter patient variability making protocolized dosage adjustment challenging. We sought to evaluate the efficacy &…
  • 2017 American Transplant Congress

    Online Patient Resources for Deceased Donor and Live Donor Kidney Recipients: A Comparative Analysis of Readability.

    E. Zhou, E. Kiwanuka, W. Cioffi, P. Morrissey.

    Department of General Surgery and Division of Organ Transplantation, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, RI

    BackgroundThe Internet has extensive online resources for kidney transplantation recipients. However, it is unclear if these materials are comprehensible for kidney transplant patients. Nearly, one-half…
  • 2017 American Transplant Congress

    Patient-Reported Barriers to the Pre-Kidney Transplant Evaluation in an At-Risk Population in the United States.

    M. Lockwood,1 W. Chon,2 M. Josephson,2 Y. Becker,2 M. Saunders.2

    1College of Nursing, University of Illinois at Chicago, Chicago, IL; 2University of Chicago Medicine, Chicago, IL

    Background: Despite our knowledge of barriers to the early stages of the transplant process, we have limited insight into patient reported barriers to the pre-kidney…
  • 2017 American Transplant Congress

    Non-Medical Factors Contributing to Racial Disparity in Kidney Transplant Wait-Listing.

    Y.-H. Ng,1 S. Pankratz,1 K. Bornemann,2 E. Croswell,2 J. Pleis,2 R. Shapiro,3 M. Unruh,1 L. Myaskovsky.2

    1Medicine, Nephrology, University of New Mexico, Albuquerque, NM; 2Department of Medicine, University of Pittsburgh, Pittsburgh, PA; 3Department of Surgery, Mount Sinai Hospital, New York, NY

    Background: African American (AA) and other minorities (OM) are known to have disproportionately higher incidence of end-stage kidney disease (ESKD) but lower rates of kidney…
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