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Articles tagged "African-American"

  • 2018 American Transplant Congress

    Facilitators and Barriers to Patient Portal Use among Pre- and Post-Kidney Transplant Patients at an Urban Center in the United States

    M. Lockwood,1 K. Dunn-Lopez,1 H. Pauls,1 L. Burke,1 Y. Becker,2 M. Saunders.2

    1Biobehavioral Health Science, University of Illinois at Chicago College of Nursing, Chicago, IL; 2Department of Medicine/Surgery, University of Chicago, Chicago, IL.

    Background: As health information becomes digitized it is critical to understand the nuances of patient technology use in order to promote the use of electronic…
  • 2018 American Transplant Congress

    Impact of the New Kidney Allocation System A2/A2B –> B Policy on Access to Transplantation among Minority Candidates

    M. Mustian,1 P. Martins,2 P. MacLennan,1 J. Ortiz,2 J. Caicedo,2 S. Gray,1,2 B. Kelly,2 C. Esquivel,2 ASTS Diversity Affairs Commmittee,2 J. Locke.1,2

    1University of Alabama at Birmingham, Birmingham; 2ASTS Diversity Affairs Committee, Arlington.

    Introduction: Blood group B kidney transplant candidates, many of whom represent ethnic minorities, have historically had diminished access to deceased donor kidney transplantation (DDKT). However,…
  • 2018 American Transplant Congress

    A Theoretical Framework to Explain Factors That Impact Completion of the Medical Evaluation Process for African American (AA) End-Stage Renal Disease (ESRD) Patient

    C. Nonterah,1 H. Gardiner,2 D. Vavra.1

    1Psychology, University of Richmond, Richmond, VA; 2Department of Social and Behavioral Sciences, Temple University, Philadelphia, PA.

    Black/African Americans (B/AA) are less likely to seek kidney transplantation or complete the pre-transplant medical evaluation despite higher prevalence rates of end-stage renal disease (ESRD).…
  • 2018 American Transplant Congress

    Investigation of Lower Treatment Failure Rate Seen among Black Kidney Recipients on LCP-Tacrolimus vs. IR-Tacrolimus: Subgroup Analyses of Two Phase 3 Trials

    T. Sparkes,1 B. Masters,1 C. Staino,2 S. Patel,2 M. Cooper.3

    1University of Maryland, Baltimore, MD; 2Veloxis, Cary, NC; 3Medstar Georgetown Transplant Institute, Washington, DC.

    Black kidney transplant recipients are recognized as high risk for inferior allograft survival due to immunologic and non-immunologic factors. Pooled data from 2 Phase 3…
  • 2018 American Transplant Congress

    Is BMI > 35 a Barrier to Kidney Transplantation?

    D. Walczak, E. Benedetti, C. Ryan.

    Organ Transplant, University of Illinois, Chicago, IL.

    Background:Although lower rates of patient and graft survival are reported for kidney transplant recipients with BMI > 35, kidney transplant in this group provides a…
  • 2018 American Transplant Congress

    The Impact of Early versus Late Clinical Outcomes on Disparities in African-American Kidney Transplant Recipients

    D. Taber, J. Fleming, Z. Su, P. Mauldin, J. McGillicuddy, S. Nadig, V. Rohan, P. Baliga, D. Dubay.

    MUSC, Charleston, SC.

    Background: It is important to better understand the impact of early and late clinical events on disparities in African-American (AA) kidney transplant (KTX), which will…
  • 2018 American Transplant Congress

    Validation of Genetic Variants Identified in GWAS for Tacrolimus Troughs

    P. Jacobson,1 D. Schladt,2 W. Guan,3 J. van Setten,6 R. Remmel,4 B. Wu,3 C. Dorr,5 B. Keating,7 D. Ikle,9 R. Mannon,10 A. Matas,8 A. Israni,5 W. Oetting.1

    1Experimental and Clinical Pharmacology, Univ of MN, Minneapolis, MN; 2Chronic Disease Research Group, Minneapolis Medical Research Foundation, Hennepin County Medical Center, Minneapolis, MN; 3Division of Biostatistics, Univ of MN, Minneapolis, MN; 4Medicinal Chemistry, Univ of MN, Minneapolis, MN; 5Medicine, Hennepin County Medical Center, Minneapolis, MN; 6Cardiology, University Medical Center Utrecht, Utrecht, Netherlands; 7Surgery, Univ of Pennsylvania, Philadelphia, PA; 8Surgery, Univ of MN, Minneapolis, MN; 9Rho Inc, Chapel Hill, NC; 10Department of Medicine and Surgery, Univ of Alabama, Birmingham, AL.

    Purpose: Tacrolimus (TAC) is a substrate for CYP3A4/5 enzymes. It is well-known that variants in these genes are associated with variability in TAC trough concentrations.…
  • 2018 American Transplant Congress

    Non-Medical Factors Predict Receipt and Type of Kidney Transplant in Veterans

    K. Kendall, X. Li, C.-C. Chang, J. Pleis, E. Croswell, M. Dew, G. Switzer, A. Langone, A. Mittal-Henkle, S. Saha, M. Ramkumar, J. Adams-Flohr, C. Thomas, L. Myaskovsky.

    VA Kidney Transplant Centers: IA, OR, PA, TN, Iowa City, Portland, Pittsburgh, Nashville.

    Background: African Americans, Hispanic Americans and other minorities have a higher incidence of end-stage kidney disease but lower rates of both deceased and living donor…
  • 2018 American Transplant Congress

    Does One Size Fit All? Implementing a Protocolized Ambulatory Tacrolimus Dosing Strategy in a Predominantly African American Renal Transplant Population

    L. Gylten, C. Mardis, D. Taber, H. Meadows, C. Perez, Z. Elmaasarani, J. Fleming, N. Patel, P. Baliga, V. Rao, V. Rohan, N. Pilch.

    Medical University of South Carolina, Charleston, SC.

    Introduction: African American (AA) KTx recipients have significant tacrolimus (FK) inter patient variability making protocolized dosage adjustment challenging. We sought to evaluate the efficacy &…
  • 2018 American Transplant Congress

    Prevalence and Impact of CYP3A5 Genomic Variances on Clinical Outcomes among African-American Kidney Transplant Recipients

    A. Maldonado,1 S. Hudson,2 L. Rebellato,2 T. Asempa.1

    1Vidant Medical Center, Greenville, NC; 2East Carolina University, Greenville, NC.

    Introduction: Kidney transplantation in African American (AA) recipients continues to demonstrate inferior outcomes when compared with other race/ethnicities. Contributing factors encompass differences in pharmacogenomics, and…
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