2018 American Transplant Congress » Poster Session D: Immunosuppression Preclinical Studies

6:00pm-7:00pm

Ex Vivo Bloodless Oxygen Carrier for Perfusion of DCD Kidneys during Subnormothermic Storage

P. Luke,^1,2 M. Richard-Mohamed,² A. Haig,³ R. Mayer,² S. Aquil,² A. Sener,² A. Jevnikar,^1,2 R. Bhattacharjee.^1,2

6:00pm-7:00pm

A Natural Herb Danshen Suppresses Allospecific Memory CD8+ T Cell Generation and Murine Allograft Rejection

Z. Dai, H. Liu, Y. Chen, C-.L. Liang, F. Qiu.

6:00pm-7:00pm

Characterization of Mesenchymal Stem Cell Phenotype and Its Immunomodulatory Effects during Allo-Specific T Cell Immune-Responses

Q. Gao, A. Kirk, H. Xu.

6:00pm-7:00pm

Comparison of Temperatures for Optimal Preservation of Donor Kidneys during Oxygenated Pulsatile Perfusion

R. Bhattacharjee,¹ M. Richard-Mohamed,² A. Ruthirakanthan,³ R. Mayer,² S. Luke,³ H. Sharma,² M. TunAbraham,² B. Alharbi,² A. Haig,² P. Luke.^1,2,3

6:00pm-7:00pm

Dehydropeptidase-Iinhibitor Reduces Tacrolimus-Induced Kidney Injury by Anti-Oxidative and Anti-Apoptotic Effect

K. Luo,¹ S. Lim,¹ J. Il,¹ Y. Shin,¹ E. Ko,^1,2 B. Chung,^1,2 H. Hwang,^1,2 C. Yang.^1,2

6:00pm-7:00pm

Effect of Conversion to CTLA4Ig Treatment on Tacrolimus-Induced Diabetic Rats

J. Il,¹ L. Jin,¹ K. Luo,¹ S. Lim,¹ Y. Shin,¹ E. Ko,^1,2 B. Chung,^1,2 C. Yang.^1,2

6:00pm-7:00pm

Evaluation of Drug Action on IgM Memory B Cell Survival and Growth In Vitro; -Application for Individualized Immunosuppression after Kidney Transplants-

Y. Matsuda,¹ K. Takahashi,¹ R. Imamura,² N. Nonomura,² Y. Yuzawa.¹

6:00pm-7:00pm

Exenatide Reduces Ischemia/Reperfusion Injury in Donation after Cardiac Death Rat Kidney Transplantation

H. Yang,¹ Y. Shi,² X. Li,¹ C. Long,¹ Z. Xu,¹ L. Luo,¹ W. Luo,¹ Y. Zhang,¹ T. Zeng,³ M. Chen,⁴ H. Li,⁵ Z. Wang.⁵

6:00pm-7:00pm

Graft Perfusion with Alvespimycin, an HSP90 Inhibitor, Suppresses Acute Allograft Rejection and Prolongs Graft Survival in Murine Heart Transplantation

T. Tanaka, T. Maehana, N. Masumori.

6:00pm-7:00pm

Humoral Immunity to CMV Remains Intact after Dual Targeting Desensitization in Allosensitized Nonhuman Primates

P. Schroder, B. Ezekian, F. Saccoccio, J. Yoon, M. Dennis, K. Freischlag, J. Kwun, S. Permar, S. Knechtle.

6:00pm-7:00pm

Immune Modulatory Effect of Thalidomide and Dexamethasone Co-Treatment on Murine Splenocytes

E. Kim,^1,2 J. Kim,¹ K. Huh,^1,3 Y. Cho,¹ M. Kim,^1,3 Y. Kim,^1,3 B. Kim.^1,4

6:00pm-7:00pm

Klotho Enhances FoxO3-Mediated Manganese Superoxide Dismutase Expression by Negatively Regulating PI3K/AKT Pathway during Tacrolimus-Induced Oxidative Stress

S. Lim,¹ K. Luo,¹ J. Il,¹ Y. Shin,¹ E. Ko,^1,2 B. Chung,^1,2 C. Yang.^1,2

6:00pm-7:00pm

Mycophenolic Acid Reduces BK Polyomavirus Replication in an In Vitro Model of Renal Tubular Epithelial Cells Infection

E. Favi,¹ S. Delbue,² C. Colico,¹ P. Ferrante,² S. Villani,² I. Perna,² N. Mondoni,² A. Giussani,¹ M. Ferraresso.¹

6:00pm-7:00pm

Persistence and Homing of Autologous Donor-Reactive Ex-Vivo Expanded Regulatory T Cells to Heart Allografts in Lymphodepleted Recipient Monkeys

M. Ezzelarab, Z. Hong, A. Zahorchak, L. Lien, T. Nakao, H. Dai, D. van der Windt, A. Perez-Gutierrez, J. Bhama, A. Thomson.

6:00pm-7:00pm

Rhesus-Specific Anti-Thymocyte Globulin as an Adjuvant to Costimulatory-Blockade-Based Immunotherapy

M. Mulvihill,¹ B. Ezekian,¹ Q. Gao,¹ K. Samy,¹ R. Davis,¹ F. Leopardi,¹ A. Belli,² W. Flores,² A. Buzby,² K. Reimann,² B. Collins,¹ A. Kirk.¹

6:00pm-7:00pm

Tacrolimus-Based Maintenance Immunosuppression Decreases the Number of Peripheral Blood Transitional B Cells in Nonhuman Primates

J. Paster, K. Pruner, M. Hanekamp, J. O., W. Sommer, K. Robins, A. Bean, G. Benichou, J. Madsen.

6:00pm-7:00pm

Targeting Calcium Release-Activated Calcium (CRAC) Channel in Non-Human Primate Kidney Transplantation

J. Kwun,¹ B. Ezekian,¹ M. Manook,¹ J. Park,¹ J. Yoon,¹ J. Sloan-Lancaster,² C. Fortier,³ P. Rao,⁴ S. Knechtle.¹