2019 American Transplant Congress » Poster Session C: Innate Immunity; Chemokines, Cytokines, Complement

6:00pm-7:00pm

Alteration in Local Complement Activation in First 24h Post-Lung Transplantation (LTx) Helps Identify Recipients Developing Primary Graft Dysfunction

H. Kulkarni¹, M. Elvington², L. Ma¹, M. Cano¹, K. Pugh³, R. Hachem¹, J. Atkinson², A. Gelman³

6:00pm-7:00pm

Blockade of C3aR1 Signaling Suppresses Alloreactive CD8⁺ T Cell Immunity and Prolongs Murine Cardiac Allograft Survival

J. Horwitz, D. Mathern, P. Heeger

6:00pm-7:00pm

C1q Dominant Deposits in Renal Transplant Biopsies Are Not Associated with Allograft Dysfunction

A. Babu¹, S. Williamson², N. Khoury¹, M. Safwan¹, A. Patel¹

6:00pm-7:00pm

CHOP Deficiency Attenuated Acute Liver Injury by Promoting Macrophage M2 Polarization via ATG5-Mediated Autophagy Activation

H. Zhou, R. Liu, Q. Wang, C. Shi, F. Cheng, X. Wang, L. Lu

6:00pm-7:00pm

Cellular Sources of Cytokine Production during Cold Ischemia Induced AKI after Kidney Transplant

S. Jain¹, R. Plenter², T. Nydam², A. Jani¹

6:00pm-7:00pm

Cyclo (his-pro) Protects Against Gentamicin Induced Cell Apoptosis And Cisplatin Induced Acute Kidney Injury Through Inhibiting P53 Mediated Apoptotic Pathway.

Y. Kim¹, J. Moon¹, J. Jeong¹, J. Kim¹, S. Lee¹, M. Yu², C. Lee³, Y. Kim¹, S. Yang⁴

6:00pm-7:00pm

Deficiency of IRE1a Ameliorates Renal Allograft Injury via Remodeling of Graft-Infiltrating Macrophages

L. Qiu¹, J. Wang¹, X. Yeap¹, S. Han¹, F. Zheng¹, D. Fang², Z. J. Zhang¹

6:00pm-7:00pm

EBV Latent Proteins Encode for Peptides That Prevent Natural Killer Cell Inhibition

B. Mbiribindi¹, J. K. Pena¹, O. Hatton², C. Romero Moreno¹, C. O. Esquivel¹, O. M. Martinez¹, S. M. Krams¹

6:00pm-7:00pm

Endothelial Cells Do Not Regulate Expression of CD46, CD55 and CD59 in the Presence of Anti-HLA Class I and 11 Antibodies

A. Babu¹, T. Pham², M. Hamdorf², V. Jucaud², M. Everly², S. Daga³, D. Mitchell⁴

6:00pm-7:00pm

Expansion of Myeloid Derived Suppressor Cells Following Alum Administration

A. G. Cuenca, N. J. Feeney, K. Deng, C. G. Rickert, J. F. Markmann

6:00pm-7:00pm

Hyperglycemia Aggravates Acute Liver Injury by Promoting Macrophage NLRP3 Activation via AMPK/mTOR-Dependent Autophagy Inhibition

H. ZHOU, Q. Wang, R. Liu, S. Zhou, F. Cheng, X. Wang, L. Lu

6:00pm-7:00pm

Ikaros/IRF4 Signaling Regulates SIRT1-Mediated Macrophage M2 Shift in Liver Ischemia-Reperfusion Injury: From Mouse-to-Human

K. Kadono¹, K. Nakamura¹, H. Hirao¹, S. Kageyama¹, K. J. Dery¹, T. Ito¹, J. Aziz¹, X. Li², B. Ke¹, R. W. Busuttil¹, J. W. Kupiec‐Weglinski¹

6:00pm-7:00pm

Inhibition of CXCR3 Expression through Blockade of STAT3 Alpha Signaling Down-Regulate Inflammation of Renal Ischemia-Reperfusion Injury

J. Kim¹, J. Park², K. Yoo², J. Moon¹, J. Jeong¹, C. Lee³, Y. Kim¹, S. Yang⁴

6:00pm-7:00pm

Initial Peritoneal sST2 Levels Are Associated with Peritoneal Failure and ST2 Blockade Mitigates TGF-β and High Glucose-Induced Peritoneal Fibrosis

Y. Kim¹, S. Lee¹, M. Yu¹, H. Lee¹, Y. Kim¹, C. Lee², R. Cha³, S. Yang⁴

6:00pm-7:00pm

Interferon Sensitivity Promotes Recovery from Acetaminophen Induced Liver Injury

S. Datta, T. Hamilton, G. C. Sen

6:00pm-7:00pm

Murine Cytomegalovirus Infection Down-Regulates Receptor Tyrosine Kinase MerTK on Macrophages to Abrogate Allograft Tolerance

S. Yu, A. Dangi, M. Burnette, X. Luo

6:00pm-7:00pm

Myeloid Derived Suppressor Cells (MDSC) Home to the Allograft and Can Control T Cell Responses

Y. S. Lee, T. Zhang, J. S. Bromberg, J. R. Scalea

6:00pm-7:00pm

Peripheral Blood Chemokine Levels in Kidney Allograft Rejection

E. Van Loon, D. Schols, S. Claes, M. Naesens

6:00pm-7:00pm

Recipient Myeloid Notch1 Disruption Shifts Neutrophil towards Anti-Inflammatory Phenotype and Protects Liver Grafts from Ischemia-Reperfusion Injury

S. Kageyama¹, H. Hirao¹, K. Kadono¹, K. Nakamura¹, K. J. Dery¹, T. Ito², D. Oncel¹, J. Aziz¹, B. Ke¹, F. M. Kaldas², R. W. Busuttil², J. W. Kupiec‐Weglinski¹

6:00pm-7:00pm

Recipient TIM4 Expression is Essential for Hepatocellular Function in Liver Transplantation

K. Kadono, S. Kageyama, H. Hirao, K. Nakamura, K. J. Dery, D. Oncel, T. Ito, B. Ke, F. M. Kaldas, R. W. Busuttil, J. W. Kupiec‐Weglinski

6:00pm-7:00pm

Soluble Fibrinogen-Like Protein 2 Regulates MDSCs Differentiation and Function in Allograft Immunity

C. Yang

6:00pm-7:00pm

Targeting Pyroptosis in Brain-Dead Donors Improves Renal Function after Transplantation in Rat

H. Yang¹, Y. Shi², X. Li¹, L. Luo¹, C. Long¹, Y. Xiong³, M. Chen⁴, J. Gao⁴, H. Li⁵, Z. Wang⁵

6:00pm-7:00pm

The Potential Role of IL-33/ST2 Pathway in Renal Allograft Rejection

M. Yu¹, Y. Kim², J. Moon², S. Lee², H. Lee², D. Kim², C. Lee³, Y. Kim², S. Yang²

6:00pm-7:00pm

Transplantation Alone Induces Myeloid-Derived Suppressor Cells Which Can Suppress T Cell Responses

Y. Lee, T. Zhang, J. S. Bromberg, J. R. Scalea

6:00pm-7:00pm

mTOR Inhibitors Enhance Antitumor Activity of Liver Resident NK Cells

J. Saparbay, Y. Tanaka, A. Seidakhmetov, H. Ohdan