2017 American Transplant Congress » Poster Session C: Antibody and B Cell

6:00pm-7:00pm

APRIL/BLyS Inhibition Reduces Donor Specific Antibody in Sensitized Mice.

B. Bolt, N. Wilson Schlei, B. Verhoven, R. Redfield.

6:00pm-7:00pm

Accelerated De-Novo Donor-Specific Antibody-Mediated Rejection in a Non-Human Primate Model of Renal Transplantation.

J. Danobeitia, P. Chlebeck, J. Torrealba, T. Zens, L. Zitur, A. D'Alessandro, L. Fernandez.

6:00pm-7:00pm

Anti-HLA I Antibody Enhances Endothelial Cell-Induced Polarization of Human Monocytes to M2a/c-Like Macrophages.

X. Wei, N. Valenzuela, M. Rossetti, E. Reed.

6:00pm-7:00pm

Blood Tfh Cells Exhibit Impaired B Cell Help in Operationally Tolerant Patients.

R. Danger,¹ A. Chenouard,¹ M. Chesneau,¹ S. Castagnet,² P. Guérif,¹ N. Degauque,¹ M. Giral,¹ S. Brouard.¹

6:00pm-7:00pm

Correlation of Complement Activating Donor Specific Antibodies as Measured by C3d and Cross-Match Status.

A. Babu,^1,2,3 N. Krishnan,² D. Briggs,³ D. Mitchell,¹ S. Daga.^1,2,4

6:00pm-7:00pm

Detection of Specific B Cell Memory to the Perlecan LG3 Antigen in the Normal Immune Repertoire.

L. Padet,^1,2,3 M. Dieude,^1,2 B. Yang,^1,2,3 J. Turgeon,^1,2 H. Cardinal,^1,2 M.-J. Hebert.^1,2,3

6:00pm-7:00pm

Development of an Anti-HLA Antibody-Producing Humanized Mouse Model.

S. Yanagawa, H. Tahara, H. Ohdan.

6:00pm-7:00pm

Differential Effect of Antibody Removal on ABO Blood Group Type Chain Specific Antibodies Over Time.

A. Bentall,¹ M. Jeyakanthan,² J. Pearcey,² B. Motyka,² C. Cairo,³ T. Lowary,³ J. Buriak,⁴ L. West,² S. Ball.¹

6:00pm-7:00pm

Differential Suppressive Effects of Costimulatory Blockade (CD28/B7), Anti-IL6R, Bruton's Tyrosine Kinase and Janus Kinase Inhibition on De Novo vs. Recall Alloantibody Responses: Are Combined Drug Therapy Approaches Desirable?

I. Kim, G. Wu, N.-N. Chai, A. Klein, S. Jordan.

6:00pm-7:00pm

Effect of Two Anti-CD20 Abs on B Cell Depletion and Reconstitution in Non-Human Primates.

W. Sun,¹ N. O'Neill,¹ T. Zhang,¹ G. Braileanu,¹ K. Reimann,² R. Pierson,¹ A. Azimzadeh.¹

6:00pm-7:00pm

Effects of Anti-HLA Antibodies on Endothelial Expression and Serum Levels of Thrombomodulin in Kidney Recipients.

S. Beland, O. Desy, P. Valin, S. De Serres.

6:00pm-7:00pm

Effects of Tofacitinib (JAK-3 Inhibitor) on De Novo HLA-A2 Antibody Production in a Mouse Model of Allo-Sensitization.

N.-N. Chai, G. Wu, I. Kim, A. Klein, S. Jordan.

6:00pm-7:00pm

Improved Mouse Renal Transplantation Model Simulating Clinical Antibody Mediated Rejection.

D. Zhao, S. Li, T. Liao, X. Hua, F. Han, Z. Luo, X. Liu, Q. Sun.

6:00pm-7:00pm

Inhibition of Memory T Cell Alloresponses by TIM-1+ B Cells.

B. Gonzalez-Nolasco, H. Tector, J. Markmann, G. Benichou.

6:00pm-7:00pm

Novel Insights into the Synergism of CD40 Autoantibodies and suPAR in Kidney Transplant Patients with FSGS Recurrence.

T. Sigdel, C. Wei, F. Vencenti, J. Reiser, M. Sarwal.

6:00pm-7:00pm

Positive Flow Crossmatch After Negative Virtual Crossmatch -A Single Center Experience.

Q. Xu, S. Leckie.

6:00pm-7:00pm

Prevention of Donor Specific Antibody Production After Skin Allografting by Mobilization of Endogenous Stem Cells Using a Combination of AMD3100 and Low-Dose FK506 in Rats.

A. Ahmadi,¹ L. Qi,¹ R. Wesson,¹ F. Dor,² J. Burdik,¹ B. Philosophe,¹ G. Williams,¹ A. Cameron,¹ Z. Sun.¹

6:00pm-7:00pm

Triptolide Alleviating Acute Antibody Mediated Rejection by Inhibition of B Cell Activation in Presensitized Recipients.

D. Zhao,¹ S. Li,¹ T. Liao,¹ Y. Wei,² X. Hua,¹ F. Han,¹ Z. Luo,¹ X. Liu,¹ Q. Sun.