2022 American Transplant Congress » Machine Perfusion and Organ Rehabilitation - Basic

7:00pm-8:00pm

Cell-Free DNA Concentration in Hypothermic Machine Perfusate is a Potential Rapid Marker for Kidney Graft Quality

S. Duarte¹, M. Willman¹, V. Boominathan¹, D. Lewis¹, W. De Faria¹, G. Vrakas¹, A. El-Hinnawi¹, T. Beduschi¹, N. Battula², A. Zarrinpar¹

7:00pm-8:00pm

Cold Stress-Induced Ferroptosis in Liver Sinusoidal Endothelial Cells Deteriorates Liver Transplant Outcomes

H. Kojima, H. Hirao, K. Kadono, T. Ito, K. J. Dery, F. Kaldas, J. Kupiec-Weglinski

7:00pm-8:00pm

Comparison of Vasodilators in Dual Vessel Normothermic Ex Vivo Liver Machine Perfusion of Rat Liver Grafts

J. M. Gassner, F. Strobl, J. Michelotto, K. Kristina, V. Muth, M. Zimmer, L. Gilles, S. Moosburner, J. Pratschke, I. Sauer, N. Raschzok

7:00pm-8:00pm

Defatting of Steatotic Liver Grafts by Normothermic Ex Vivo Liver Machine Perfusion with 2,4 Dinitrophenol

J. M. Gassner¹, J. Michelotto¹, S. Moosburner¹, F. Strobl¹, A. L. Birkenfeld², A. Kurzbach², G. Shulman³, X. Zhang³, M. Selzner⁴, Y. Noguchi⁴, J. Pratschke¹, I. M. Sauer¹, N. Raschzok¹

7:00pm-8:00pm

Development of Ex-Situ Hypothermic and Normothermic Reperfusion as an Innovative Method to Preserve an Assess Uterus: A Preliminary Result

L. Dion¹, E. Loiseau², B. Mesnard³, G. Blancho⁴, T. Thubert⁵, J. Hervouet⁴, D. Minault⁴, S. Le Bas-Bernardet⁶, R. Josien⁶, V. Lavoué¹, J. Branchereau⁷

7:00pm-8:00pm

Early Experience Of 48-hour Normothermic Machine Perfusion In Human Kidneys Applying Urine Recirculation

F. Messner¹, S. Gasteiger¹, M. Pühringer-Sturmayr¹, A. Soleiman¹, D. Öfner¹, S. Schneeberger¹, A. Weissenbacher²

7:00pm-8:00pm

Exploration of the Optimal pH in Hypothermic Machine Perfusion for Rat Liver Grafts Retrieved from Circulatory Death

S. Sakamoto¹, M. Fukai¹, K. Shibata¹, H. Bochimoto², N. Mohd Zin², N. Kawamura¹, T. Ishikawa¹, M. Fujiyoshi¹, T. Shimamura³, A. Taketomi¹

7:00pm-8:00pm

Fibrin Deposition in Ischemic Damaged Liver Grafts and Reconditioning with Thrombolytic Therapy During Normothermic Machine Perfusion

T. Goto, Y. Noguchi, S. Ganesh, B. Arulratnam, M. Kawamura, C. Parmentier, S. Ray, T. Reichman, N. Selzner, M. Selzner

7:00pm-8:00pm

Growing Use of Perfusion for Heart, Liver, and Lung and Early Outcomes

R. R. Goff¹, K. Gauntt¹, W. Cherikh¹, E. D. Lease², D. Klassen¹

7:00pm-8:00pm

Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Porcine Pancreas Grafts

C. Parmentier, S. Ray, L. Mazilescu, M. Kawamura, T. Goto, Y. Noguchi, B. Arulratnam, S. Ganesh, M. Selzner, T. Reichman

7:00pm-8:00pm

Normothermic Ex Vivo Perfusion of Discarded Human Pancreases: A Feasibility Study to Expand the Pancreas Donor Pool

C. Parmentier, S. Ray, L. Mazilescu, M. Kawamura, Y. Noguchi, T. Goto, B. Arulratnam, S. Ganesh, M. Selzner, T. Reichman

7:00pm-8:00pm

Performance of Aged Liver Grafts in a Rat Model of Normothermic Ex Vivo Liver Machine Perfusion

S. Moosburner¹, M. Zimmer¹, J. M. Gassner¹, N. Roschke¹, N. Berndt², J. Michelotto¹, K. H. Hillebrandt¹, J. Pratschke¹, I. M. Sauer¹, N. Raschzok¹

7:00pm-8:00pm

Perfusate Cell-Free DNA Content is a Potential Marker of Cellular Injury During Hypothermic Machine Perfusion of Porcine Kidneys Subject to Prolonged Warm Ischemia

V. Boominathan¹, M. Willman¹, N. Battula², A. Zarrinpar¹, S. Duarte¹

7:00pm-8:00pm

Regulation of Cell Death During Cold Preservation of Marginal Human Kidneys

J. R. DiRito¹, G. Chickering¹, J. Langford¹, D. Stern¹, D. Qin², S. Hosgood³, M. Nicholson³, J. Pober⁴, E. Gavathiotis⁵, R. Kitsis⁵, G. Tietjen¹

7:00pm-8:00pm

Stabilization of Cell-Cell Junctions Improves Outcomes in an Ex-Vivo Porcine Renal Ischemia-Reperfusion Injury Culture Model

L. Plumblee¹, K. Patel², L. Langerude³, Z. Tu³, D. Nord⁴, T. Beduschi³, S. Nadig⁵, C. Atkinson⁶

7:00pm-8:00pm

Ultrasound Targeted Microbubble Cavitation During Ex Vivo Normothermic Machine Perfusion Reduces Peribiliary Vascular Plexus Thrombi and Graft Injury in a DCD Liver Transplant Model

Y. Nigmet¹, C. Hughes¹, X. Chen², A. Demetris³, D. Stolz⁴, J. Pacella², A. Humar⁵, F. Villanueva²

7:00pm-8:00pm

Xenogeneic Cross-Circulation Supports Ex Vivo Human Livers for 24 Hours

W. K. Wu¹, R. Ukita², Y. J. Patel², I. A. Ziogas³, M. Cortelli², M. Mentz², J. R. Talackine², S. A. Francois², N. L. Cardwell², J. W. Stokes², S. P. Alexopoulos³, M. Bacchetta²