2022 American Transplant Congress » Machine Perfusion and Organ Rehabililtation - Basic

5:30pm-5:40pm

Local Mesenchymal Stem Cell Therapy for the Ex Vivo Preservation of a Porcine Vascularized Composite Allograft with 24-hour Normothermic Machine Perfusion

A. Bernal¹, J. Hinshaw¹, J. Pena¹, C. Hinshaw¹, D. Wood¹, K. Zimmern², N. McMahon², J. Ling², W. Zhang¹, E. Weitzel¹

5:40pm-5:50pm

Novel Portable Hypothermic Cardiac Preservation Device Enhances Cardiac Viability and Function of the Isolated Porcine Hearts

K. Andrijauskaite, R. J. Veraza, R. P. Lopez, E. C. Cisneros, I. J. Jessop, M. D. Watt, L. Bunegin

5:50pm-6:00pm

Sigma-1 Receptor Agonists Are Protective in a Rat Model of Kidney Transplantation

A. Hosszu¹, T. Lakat¹, A. Toth¹, J. Hodrea¹, L. Wagner², A. J. Szabo¹, A. Fekete¹

6:00pm-6:10pm

Enhanced Delivery of Nanomedicine to Human Kidney During Ex Vivo Perfusion

C. Albert¹, L. Bracaglia¹, A. Koide², J. R. DiRito¹, T. Lysyy¹, E. Christopher¹, J. Grundler¹, J. T. Langford¹, D. Haakinson¹, J. S. Pober¹, W. M. Saltzman¹, S. Koide², G. Tietjen¹

6:10pm-6:20pm

Perfusate Metabolites and Association with Pump Perfusion and Allograft Failure

R. X. Liu¹, N. Koyawala², H. T. Philbrook², I. Hall³, P. Reese⁴, S. Mohan⁵, M. Doshi⁶, C. Parikh¹

6:20pm-6:30pm

Analysis of Tissue and Effluent Damage Associated Molecular Patterns Following Hypothermic Oxygenated Machine Perfusion vs Static Cold Storage in Liver Transplantation

G. G. Panayotova, Y. Qin, S. Simonishvili, T. Ayorinde, F. Paterno, L. Brown, A. Amin, K. E. Lunsford, J. V. Guarrera

6:30pm-6:40pm

Artificial Mitochondria Transfer to Mitigate Ischemic Damage in an In Vitro Model of Tubular Injury and in an Ex Vivo Porcine Model of DCD Renal Transplantation

A. Rossi¹, S. Sedrakyan², F. Montali³, C. Aardena⁴, N. Abraham⁵, A. Barbas⁵, L. N. Byers⁶, C. Palles⁷, A. Asthana⁶, J. Robertson⁴, L. Perin², R. Senger⁴, B. Bussolati¹, G. Orlando⁸

6:40pm-6:50pm

Hepatocyte SIRT1 Regulation of Apoptosis-Mediated Pyroptosis Cell Death in Mouse and Human Liver Transplantation

K. Kadono¹, H. Hirao¹, H. Kojima¹, K. J. Dery¹, X. Li², J. Kupiec-Weglinski¹

6:50pm-7:00pm

Delivery of Plasmin During Machine Perfusion or Cold Storage Flush Improves Early Transplant Outcomes in aRat Dcd Liver Transplant Model

N. Abraham¹, M. Zhang¹, P. Cray², R. Neill¹, G. Cywinska¹, J. Migaly¹, R. Kahan¹, A. Pontula¹, J. Penaflor¹, Q. Gao¹, K. P. Samy¹, J. J. Pollara², V. Novokhatny³, M. G. Hartwig¹, A. S. Barbas¹