2022 American Transplant Congress » Immunosuppression and Tolerance: Preclinical and Translational Studies

Date: Sunday, June 5, 2022

Time: 5:30pm-7:00pm

Location: Hynes Ballroom A

Session Type: Rapid Fire Oral Abstract

Meeting: 2022 American Transplant Congress

5:30pm-5:40pm: Ex Vivo Modification of Vascular Allografts Using Immunosuppressive and Anti-Inflammatory Polymers Prevent Rejection via Localized Immunosuppression

H. D. Luo¹, E. M. Siren¹, W. Enns², L. Sim¹, C. Du¹, S. G. Withers¹, J. Choy³, J. N. Kizhakkedathu¹

5:40pm-5:50pm: Achievement of Persistent Mixed Chimerism in Recipients of Matched and Mismatched Living Donor Kidney Transplants in a Tolerance Induction Protocol

J. D. Scandling, S. Busque, R. Lowsky, T. Pham, R. Hoppe, K. Jensen, A. Shori, H. Wu, R. Pawar, E. Engleman, E. Meyer, S. Strober

5:50pm-6:00pm: Using mTOR Inhibitor Nanoimmunotherapy to Induce Cardiac Allograft Tolerance in Non-Human Primates

J. M. O¹, P. M. Patel², A. J. Teunissen³, C. L. Miller⁴, T. Costa¹, M. Momodu¹, D. Muldoon¹, A. Dehnadi¹, I. M. Hanekamp¹, V. Pothula⁵, R. Sanchez-Tarjuelo⁶, G. Prevot⁶, W. J. Mulder⁶, J. Allan⁷, J. Ochando⁸, J. Madsen⁹

6:00pm-6:10pm: Belatacept-Based Maintenance Immunosuppression Promoted Long-Term Antibody-Mediated Rejection Free Graft Survival After Desensitization in Sensitized Multiparous Female Recipients

M. Manook, I. Anwar, R. Schmitz, Z. Fitch, J. Yoon, A. Jackson, J. Kwun, S. Knechtle

6:10pm-6:20pm: MTOR Inhibition Acts Directly on Endothelial Cells to Induce Contact-Independent Immune-Modulation of Allo-Specific T Cell Activation

H. Xu, L. Wang, V. A. Bendersky, Q. Gao, Q. Li, A. D. Kirk, H. Xu

6:20pm-6:30pm: Long-Term Rejection Free Renal Allograft Survival with Fc-Modified Anti-cd154 Antibody Monotherapy in Nonhuman Primates

G. Lassiter, T. Hirose, A. D’Attilio, T. Kawai

6:30pm-6:40pm: Identification of a Unique and Mechanistic Urinary Cell mRNA Signature in Tolerant Kidney Transplant Recipients Conditioned with FCR001 Facilitating Cells

J. Lee¹, J. R. Leventhal², C. Li³, R. Ding¹, S. Ildstad⁴, M. Suthanthiran⁵

6:40pm-6:50pm: FasL-Presenting PEG Microgels Supports Sustained Graft Survival in Nonhuman Primates in the Absence of Continuous Immunosuppression

E. S. Yolcu¹, J. Lei², M. M. Coronel³, H. Deng⁴, Z. Yang⁴, A. Zhang⁴, T. Chen⁵, K. Lee⁴, C. Peters⁴, I. Rosales⁴, Z. Wang⁴, J. Markmann⁴, A. Garcia³, H. Shirwan¹

6:50pm-7:00pm: Pd-1 Licenses Activated Treg for Lymphatic Migration

W. Piao¹, L. Li¹, V. Saxena¹, K. Hippen², M. Shirkey¹, B. Blazar², I. Lape³, y. zhang³, J. Bromberg¹

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