2016 American Transplant Congress » Concurrent Session: Xenotransplantation: Animal Models

Date: Monday, June 13, 2016

Time: 4:30pm-6:00pm

Location: Room 102

Session Type: Concurrent Session

Meeting: 2016 American Transplant Congress

4:30pm-4:42pm: The Impact of Sequential Gene Modifications on Cardiac Xenograft Survival.

K. Horvath,¹ A. Singh,¹ J. Chan,¹ M. Thomas,² B. Lewis,² D. Ayares,³ P. Corcoran,¹ M. Mohiuddin.¹

4:42pm-4:54pm: Inclusion of Human Tissue Factor Pathway Inhibitor or Thrombomodulin Transgenes Attenuates Critical Consumptive Thrombocytopenia in Cardiac Xenotransplantation.

J. Chan,¹ A. Singh,¹ P. Corcoran,¹ M. Thomas III,² B. Lewis,² D. Ayares,³ K. Horvath,¹ M. Mohiuddin.¹

4:54pm-5:06pm: Costimulation Blockade by Anti CD40 Antibody Prevents Humoral and Cellular Rejection of Heterotopic Pig Cardiac Xenograft.

A. Singh,¹ J. Chan,¹ P. Corcoran,¹ B. Lewis,² M. Thomas,² D. Ayares,³ K. Horvath,¹ M. Mohiuddin.¹

5:06pm-5:18pm: Comparison of Early Engraftment Immunobiology of Xenoislets and Alloislets in a Dual Transplant Model.

K. Samy,¹ B. Martin,² M. Song,¹ B. Collins,¹ E. Gall,¹ J. Cano,² A. Farris,² F. Leopardi,¹ A. Kirk.^1,2

5:18pm-5:30pm: Porcine Islets Engineered to Display SA-FasL Protein on Their Surface Induce Tolerance in Mice Following Transplantation into the Liver or Under the Kidney Capsule.

H. Zhao,¹ K. Woodward,¹ H. Shirwan,¹ M. Graham,² B. Hering,² E. Yolcu.¹

5:30pm-5:42pm: Impact of Mixed Xenogeneic Porcine Hematopoietic Chimerism on Human NK Cell Recognition in a Humanized Mouse Model.

H. Li,¹ P. Vishwasrao,^1,2 M. Holzl,¹ S. Chen,¹ G. Choi,^2,3 G. Zhao,¹ M. Sykes.¹

5:42pm-5:54pm: Human Leukocyte Antigen-E Expression on Porcine GalTKO.hCD46 Cells Improves Ex-Vivo Xenograft Survival and Attenuates Injury.

C. Laird,¹ N. Kubicki,¹ L. Burdorf,¹ T. Zhang,¹ X. Chang,¹ G. Braileanu,¹ C. Phelps,² D. Ayares,² A. Azimzadeh,¹ R. Pierson.¹

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