2019 American Transplant Congress » Concurrent Session: Xenotransplantation

2:30pm-2:42pm

CD46 Transgene Modification and Thrombosis in Neonatal Porcine Islet Xenotransplantation

M. Song, K. Samy, Q. Gao, R. P. Davis, F. Leopard, Z. Fitch, C. Bennett, G. R. Devi, B. H. Collins, A. D. Kirk

2:42pm-2:54pm

Progress Using Genetically Engineered Pigs for Lung Xenotransplantation

L. Burdorf¹, C. Laird², S. Sendil², T. Zhang², D. Parsell², I. Tatarov², B. Cerel¹, Z. Abady¹, S. Pratts¹, C. J. Phelps³, D. L. Ayares³, A. M. Azimzadeh¹, R. N. Pierson III¹

2:54pm-3:06pm

Anti- CD154 / CD40 Costimulation Blockade is Superior to Tacrolimus in Prolonging Survival in Pig-to-Nonhuman Primate Renal Xenotransplantation

B. P. Lovasik¹, A. J. Matar¹, C. Breeden¹, J. Jenkins², J. Tector³, S. C. Kim¹, A. B. Adams¹

3:06pm-3:18pm

The Role of CD47/SIRPα and CD47/TSP-1 Pathways in Pig-to-Baboon Kidney Transplantation Using hCD47 Transgenic Kidneys

K. Takeuchi¹, Y. Ariyoshi¹, T. Pomposelli¹, L. Boyd¹, D. Ekanayake-Alper¹, S. Arn¹, R. Hawley¹, D. Ayares², M. Lorber³, M. Sykes¹, D. Sachs¹, R. Johnson⁴, K. Yamada¹

3:18pm-3:30pm

Newly-Revealed Antibody Targets Lead to the Early Loss of Triple Knockout Pig Kidneys in a Pig to Baboon Model

Y. Ariyoshi¹, K. Takeuchi¹, T. Pomposelli¹, D. K. Ekanayake-Alper¹, C. Schuetz¹, H. Sahara¹, L. Boyd¹, E. Estime¹, S. Arn¹, D. Ayares², M. Lorber³, M. Sykes¹, D. Sachs¹, K. Yamada¹

3:30pm-3:42pm

Kidney Xenotransplantation from Genetically Engineered Pigs to Baboons with FDA-Approved Immunosuppressive Therapy

T. Yamamoto¹, H. Hara¹, J. Foote¹, E. C. Klein², H. J. Schuurman³, L. Wang¹, Q. Li¹, H. Zhou¹, J. Li¹, J. A. Tector¹, Z. Zhang², M. Ezzelarab², R. Lovingood¹, D. Ayares⁴, D. E. Eckhoff¹, D. K. Cooper¹, H. Iwase¹

3:42pm-3:54pm

Utilizing Ides To Eliminate Residual Antibodies Targeting Xenografts

C. Rickert, K. Lee, N. Tanimine, J. Lei, A. Cuenca, N. Feeney, K. Deng, H. Yeh, J. F. Markmann