2015 American Transplant Congress » Concurrent Session: Transplant Tolerance: Animal Models I

Date: Monday, May 4, 2015

Time: 2:15pm-3:45pm

Location: Room 121-C

Session Type: Concurrent Session

Meeting: 2015 American Transplant Congress

2:15pm-2:27pm: Repurposing Jak/STAT Signaling Inhibition to Enhance Costimulation Blockade and Promote Transplant Acceptance

G. Raimondi, S. Khalifian, D. Miller, B. Oh, G. Furtmueller, M. Fryer, W. Lee, G. Brandacher.

2:27pm-2:39pm: Rational Development of Alloantigen Specific Regulatory T Cell Therapy Requires Insight Into Longevity of Alloimmune Pathways

J. Ali, M. Negus, E. Bolton, J. Bradley, G. Pettigrew.

2:39pm-2:51pm: IL-2/IL-2 Ab Complex Leads to Long-Term Tolerance in a Treg Dependent DST Model of Skin Allograft Transplantation in Which DST and Timing of the Antibody Complex Are Crucial

G. Zhang,¹ Y. Wang,¹ M. Hu,¹ A. Sawyer,¹ J. Zhou,¹ S. Grey,² S. Alexander.¹

2:51pm-3:03pm: Donor Specific Expansion of Regulatory T-Cells Was Associated With Allograft Tolerance Induced By Transient Mixed Chimerism in Nonhuman Primates

K. Hotta, A. Aoyama, T. Ohura, M. Tonsho, Y. Yamada, J. Allan, J. Madsen, B. Cosimi, G. Benichou, T. Kawai.

3:03pm-3:15pm: Tolerance to Graft A-Antigens Following ABO-Incompatible Heart Transplantation (HTx) in a Blood Group A-Transgenic Mouse Model

B. Motyka,¹ K. Labonte,¹ F. Rahman,¹ J. Pearcey,¹ K. Tao,¹ M. Mengel,¹ B. Sis,¹ P. Cowan,² L. West.¹

3:15pm-3:27pm: Regulatory Tolerance Across a Full MHC Barrier Is More Robust Than Tolerance Across a Class I MHC Disparity Alone

M. Madariaga, S. Michel, G. La Muraglia II, M. O'Neil, W. Orent, V. Villani, M. Sekijima, E. Farkash, R. Colvin, J. Allan, K. Yamada, J. Madsen, D. Sachs.

3:27pm-3:39pm: ALDH Expression in Facilitating Cells Plays a Critical Role in Regulatory T Cell Induction and GVHD Prevention

H. Xu,¹ T. Miller,¹ Y. Huang,¹ S. Ildstad.^1,2

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