2015 American Transplant Congress » Concurrent Session: Mechanisms of Resistance To Costimulatory Blockade

Date: Monday, May 4, 2015

Time: 4:00pm-5:30pm

Location: Room 122-AB

Session Type: Concurrent Session

Meeting: 2015 American Transplant Congress

4:00pm-4:12pm: Myeloid Cells as a Key Mediator for Impairment of Transplant Tolerance by CMV Infection

L. Zhang,¹ X. Zhang,² H. Kang,¹ X.-F. Liu,² S. Yan,² J.-J. Wang,² M. Abecassis,² Z. Zhang,² M. Hummel,² X. Luo.^1,2

4:12pm-4:24pm: Vaccine-Induced 'Incognito' CD8+ T Cell Memory Can Disrupt Transplantation Tolerance

M. Nelsen,¹ K. Beard,² R. Kedl,¹ R. Gill.²

4:24pm-4:36pm: Virus Induced CD28 Down-Regulation as a Potential Driver of Costimulation Blockade Resistant Rejection

D. Mou,¹ J. Espinosa,¹ L. Stempora,² J. Kwun,² N. Iwakoshi,¹ A. Kirk.²

4:36pm-4:48pm: Enhanced Requirement for TNF Signaling on Low Affinity Memory CD8+ T Cells During Heterologous Immunity

S. Krummey,¹ C.-W. Chen,¹ D. Liu,¹ M. Wagener,¹ B. Evavold,² C. Larsen,¹ M. Ford.¹

4:48pm-5:00pm: Eomes-Expressing CD8+ T Cells and Th17 Cells Mediate Costimulatory Blockade-Resistant Allograft Rejection in Mice

M. Sabet-Baktach,¹ E. Eggenhofer,¹ P. Renner,¹ M. Lantow,¹ H. Schlitt,¹ E. Geissler,¹ A. Kroemer.^1,2

5:00pm-5:12pm: Absence of Allograft TLR4 Receptor Signaling Attenuates Early Inflammation and Promotes Survival of Allografts Subjected to Prolonged Cold Ischemic Storage

N. Kohei,¹ T. Tanaka,¹ H. Tsuda,¹ D. Kish,¹ K. Tanabe,² R. Fairchild.¹

5:12pm-5:24pm: Defining the Role of CD57+CD4 T Cells in Belatacept-Resistant Rejection

J. Espinosa,^1,2 L. Stempora,^1,2 R. Townsend,³ A. Kirk.^1,2

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