2019 American Transplant Congress » Concurrent Session: Immunosuppression Preclinical Studies

Date: Monday, June 3, 2019

Time: 2:30pm-4:00pm

Location: Room 309

Session Type: Concurrent Session

Meeting: 2019 American Transplant Congress

2:30pm-2:42pm: Granulocyte – Colony Stimulating Factor (G-CSF) and Granulocyte – Macrophage Colony Stimulating Factor (GM-CSF) Administration Augments the Incidence of Peripheral Blood Suppressive Regulatory T Cells in Nonhuman Primates

K. Sasaki, Y. Wang, L. Lu, J. Hughs, A. W. Thomson, M. B. Ezzelarab

2:42pm-2:54pm: Mitochondrial Dysfunction and Metabolic Reprogramming: Critical Features of Cyclosporine A Nephrotoxicity

A. A. Zmijewska, G. Benavides, V. Darley-Usmar, J. W. Zmijewski, R. B. Mannon

2:54pm-3:06pm: Impact Of Selective Cd28 Blockade On Protective Immunity To A Murine Epstein-Barr Virus Homolog

R. L. Crepeau, J. A. Elengickal, M. L. Ford

3:06pm-3:18pm: Interruption of Notch Signaling via Blockade of Delta-Like Ligands 1 and 4 Prevents Co-Stimulation Blockade Resistant Allograft Rejection

A. Matar, Y. Dong, B. Lovasik, D. Mathews, A. Ghosh, C. Breeden, A. Stephenson, W. Kitchens, A. Adams

3:18pm-3:30pm: Dual Targeting Desensitization with Carfilzomib Plus Lulizumab Significantly Prolongs Kidney Transplant Survival in Allosensitized Nonhuman Primates

P. M. Schroder, R. Schmitz, Z. Fitch, B. Ezekian, J. Yoon, A. Choi, A. Barbas, F. Leopardi, B. Collins, J. Kwun, S. J. Knechtle

3:30pm-3:42pm: Graft Perfusion with Alvespimycin, an HSP90 Inhibitor, Suppresses IL-2 and IL-12p40 Production in Graft-Infiltrating Cells, Leading to Prolongation of Graft Survival in Murine Heart Transplantation

T. Tanaka, T. Maehana, N. Masumori

3:42pm-3:54pm: Utilizing Changing Patterns of T-cell Metabolism in Aging for Effective Immunosuppression

Y. Nian, T. Heinbokel, K. Minami, R. Maenosono, J. Iske, A. El Khal, S. G. Tullius

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