2018 American Transplant Congress » Concurrent Session: Cellular Therapies and to Promote Tolerance

Date: Tuesday, June 5, 2018

Time: 4:30pm-6:00pm

Location: Room 606/607

Session Type: Concurrent Session

Meeting: 2018 American Transplant Congress

4:30pm-4:42pm: HO-1 Regulates SIRT1– Autophagy Pathway in Liver Transplantation: From Mouse-to-Human

K. Nakamura,¹ S. Kageyama,¹ S. Yue,¹ A. Aziz,¹ T. Ito,¹ D. Oncel,¹ B. Ke,¹ R. Sosa,² E. Reed,² F. Kaldas,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹

4:42pm-4:54pm: Engineering Regulatory T Cells with Interleukin (IL-)2 Nanogel for Improved Alloimmune Suppression

S. Eskandari,¹ M. Bandeira Melo,² J. Assaker,¹ A. Mansouri,¹ S. Cai,¹ B. Al Dulaijan,¹ M. Mohamed,¹ D. Irvine,² J. Azzi.¹

4:54pm-5:06pm: PGE2/Beta-Catenin/XBP1 Signaling Controls Mesenchymal Stem Cell-Mediated Immune Regulation in Liver Ischemia and Reperfusion Injury

C. Li, S. Yue, L. Jiang, Q. Zhu, D. Farmer, R. Busuttil, J. Kupiec-Weglinski, B. Ke.

5:06pm-5:18pm: Ex Vivo-Expanded Human CD19⁺CD73^–CD25⁺CD71⁺TIM-1⁺ B Regulatory Cells Can Prolong Allograft Survival in a Humanized Mouse Model of Skin Transplantation and Are Dependent on TIM-1-Mediated Regulation of STAT3 Signaling

S. Shankar,¹ J. Stolp,^1,2 S. Juvet,^1,3 J. Hester,¹ K. Wood.¹

5:18pm-5:30pm: Confirmation of the Feasibility of Ex Vivo Creation of a Novel Human Multi-Chimeric Cells Therapy for Tolerance Induction in Vascularized Composite Allotransplantation

J. Cwykiel, G. Rafidi, M. Siemionow.

5:30pm-5:42pm: Ex Vivo Expanded Regulatory T Cells Combined with Short-Term Costimulation Blockade Prevent Rejection of Vascularized Composite Allografts

B. Oh,¹ G. Furtmüller,¹ M. Grzelak,¹ L. Vuong,² M. Iglesias,¹ M. Fryer,¹ D. Cooney,¹ W. Lee,¹ G. Raimondi,¹ G. Brandacher.¹

5:42pm-5:54pm: Curative Correction of FAH Deficiency by Chimeric Stem Cells Transplantation

D. Joo,^1,2 E. Nelson,¹ Y. Zhang,¹ B. Amiot,¹ S. Ho,³ C. Lancto,⁴ D. Carlson,⁴ L. Queiroz,⁵ S. Nyberg.¹

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