2017 American Transplant Congress » Concurrent Session: Basic Transplant Tolerance II

Date: Tuesday, May 2, 2017

Time: 2:30pm-4:00pm

Location: E350

Session Type: Concurrent Session

Meeting: 2017 American Transplant Congress

2:30pm-2:42pm: Mesenchymal Stem Cells Suppress T Cell Proliferation and Improve Allograft Survival in a Nonhuman Primate Transplant Model.

S. Kim, D. Mathews, L. Higginbotham, C. Breeden, C. Larsen, A. Adams.

2:42pm-2:54pm: Maintenance of the Phenotype and Abundance of Islet-Resident Macrophages Promotes Islet Graft Survival and Appears to Prevent Type 1 Diabetes.

P. Kyriazis, T. Thornley, K. Agarwal, L. Ma, T. Strom, M. Koulmanda.

2:54pm-3:06pm: Anti-CD40 mAb Promotes Kidney Immunoregulatory Capacity in NHP Transplants by Altering Kidney Tubular Cell (TEC) Expression of CD40 and IL-6.

J. Arp,¹ Y. Ma,¹ H. Yang,² A. El Warrak,¹ A. Haig,¹ W. Liu,¹ K. Reimann,³ P. Luke,¹ Z. Zhang,¹ D. Rothstein,⁴ A. Jevnikar.¹

3:06pm-3:18pm: Prominence of Graft-Infiltrating PD-L1^hi Cross-Dressed Dendritic Cells in Mouse Liver Transplant Tolerance.

Y. Ono, A. Perez Gutierrez, S. Yokota, O. Yoshida, T. Nakao, G. Camirand, D. Geller, A. Thomson.

3:18pm-3:30pm: Combination αCD28+αCD40 Costimulation Blockade Attenuates Acute and Chronic Rejection in Non-Human Primates.

N. O'Neill, T. Zhang, W. Sun, G. Braileanu, X. Cheng, I. Tatarov, W. Hassanein, A. Azimzadeh, R. Pierson.

3:30pm-3:42pm: Abrogating MyD88 Signaling in Donor Lung Resident Hematopoietic Cells Promotes Cell Based Tolerance Induction in Lung Allografts in Mice.

Z. Zheng,¹ J. Wang,¹ X. Yeap,¹ L. Li,³ L. Zhang,² M. He,¹ X. Luo,² Z. Zhang.¹

3:42pm-3:54pm: Dual Costimulatory Blockades Failed to Achieve Transplant Tolerance Despite Induction of Mixed Chimerism in NHPs.

T. Oura,¹ K. Hotta,¹ I. Rosales,² A. Dehnadi,¹ J. Lei,¹ J. James Markmann,¹ M. Matsunami,¹ J. Paster,¹ I. Hanekamp,¹ K. Pruner,¹ K. Kawai,¹ D. Ndishabandi,² R.-N. Smith,² B. Cosimi,¹ T. Kawai.¹

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