2016 American Transplant Congress » Concurrent Session: B cells and Antibody-Mediated Rejection: Animal Models

Date: Tuesday, June 14, 2016

Time: 4:30pm-6:00pm

Location: Room 309

Session Type: Concurrent Session

Meeting: 2016 American Transplant Congress

4:30pm-4:42pm: Allo-Specific Memory B Cell Recall Responses Are Dependent on B Cell Autophagy.

J. Leventhal,¹ M. Fribourg,² J. Ni,¹ P. Heeger.¹

4:42pm-4:54pm: Designing and Synthesizing a Novel Highly Selective Immunoproteasome Inhibitor That Promotes Long Term Heart Allograft Acceptance While Reducing Plasma Cells and Donor Specific Antibodies.

A. Mihali,¹ E. Sula Karreci,¹ A. Kurdi,³ L. Riella,¹ Y. Kawano,³ H. Fan,² P. Singh,² I. Ghobrial,³ C. Nathan,² G. Lin,² J. Azzi.¹

4:54pm-5:06pm: Selective Deletion of Notch2 on B Cells Abrogates Alloantibody Production in Fully MHC-Mismatched Cardiac and Skin Transplant Models.

N. Murakami, C. Magee, T. Borges, J. Azzi, L. Riella.

5:06pm-5:18pm: CTLA4 Negatively Regulates Donor-Reactive CXCR5+PD1+ T Follicular Helper Cell Responses Following Transplantation.

I. Badell,¹ D. Liu,¹ S. Suchard,² S. Nadler,² M. Ford.¹

5:18pm-5:30pm: Differential Regulation of the Microvascular Endothelial Cell Mediated Allogeneic CD4+ T Cell Response by Anti-HLA-DR and -DQ Alloantibodies in an Inflammatory Context.

N. Mooney,^1,2 A. Cross,^1,2 J. Lion,^1,2 A. Haziot,^1,2 D. Glotz.^1,2,3

5:30pm-5:42pm: NK Cells Play a Critical Role in Mediating Inflammation and Graft Failure During Antibody-Mediated Rejection of Kidney Allografts.

T. Tanaka,^1,2 N. Kohei,¹ N. Dvorina,¹ A. Valujskikh,¹ W. Baldwin 3rd,¹ R. Fairchild.¹

5:42pm-5:54pm: Metallothionein Accelerates Anti-MHC Induced Small Airway Obliteration and Fibrosis by Negatively Regulating IL-10 and Regulatory Cells.

D. Nayak,^1,2 F. Zhou,¹ N. Benshoff,¹ T. Mohanakumar.^1,2

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