2022 American Transplant Congress » B-cell / Antibody /Autoimmunity

Date: Monday, June 6, 2022

Time: 7:00pm-8:00pm

Location: Hynes Halls C & D

Session Type: Poster Abstract

Meeting: 2022 American Transplant Congress

7:00pm-8:00pm: Alloprimed Antibody-Suppressor CD8⁺ TCells Preferentially Kill Alloprimed Germinal Center B Cells

J. Zimmerer, S. Chaudhari, G. Bumgardner

7:00pm-8:00pm: Anti-CD80/86 Antibody (RM80/GL-1) Suppressed Murine Donor Specific Antibody Through Anergy CD4⁺T Cells

Y. Yamamoto¹, K. Uchida², K. Iguchi¹, M. Niimi³, M. Uchiyama¹

7:00pm-8:00pm: Assessment of Circulating B Cell Developmental Stages Early After Kidney Transplantation. Preliminary Data from a Single Center

A. Fouza¹, A. Fylaktou², A. Xohelli², E. Sampani³, B. Nikolaidou², D. Asouhidou², N. Antoniadis¹, E. Kasimatis³, M. Stangou³, G. Tsoulfas¹, A. Papagianni³

7:00pm-8:00pm: Bone Marrow Resident Long-Lived Plasma Cells as Source of Chronic Donor-Specific Antibodies

M. Muckenhuber, S. Pichler, A. M. Weijler, T. Wekerle

7:00pm-8:00pm: Characterization Of Local Antibody Responses In Human Cardiac Allograft Vasculopathy

S. B. See¹, L. J. Stanton¹, P. Roy¹, S. Mashiko¹, E. R. Vasilescu², C. C. Marboe², M. Szabolcs², M. V. Habal³, M. Farr³, S. Restaino³, Y. Naka⁴, D. M. Mancini⁵, J. C. Madsen⁶, R. G. King⁷, E. P. Kransdorf⁸, E. Zorn¹

7:00pm-8:00pm: Circulating Antibodies in CMV Viremia in Kidney Transplantation

T. Sigdel¹, P. Velpurisiva¹, V. Dharnidharka², M. M. Sarwal¹

7:00pm-8:00pm: Circulating and Intragraft Donor (HLA)-Specific B Cells Drive Allograft Rejection After Kidney Transplantation

A. Torija¹, N. Bolaños¹, L. Donadeu¹, M. Meneghini², I. Torres², A. Gabaldon², M. Gomà³, E. Crespo¹, F. Moreso⁴, O. Bestard²

7:00pm-8:00pm: Comparison of IGG and IGM Type B Cell Receptor-Mediated MTOR Phosphorylation Signal

Y. Matsuda

7:00pm-8:00pm: Complement 5 Regulation Ameliorates Antibody-Mediated Rejection After Liver Transplantation in Rats

T. Tajima¹, K. Hata¹, J. Kusakabe¹, H. Miyauchi¹, X. Zhao¹, S. Kageyama¹, T. Okamoto¹, Y. Wang², E. Hatano¹

7:00pm-8:00pm: Contributions of Allogenicity and Antigen Presentation to Regulatory B Cell Suppression

K. Lee, F. Qiang, K. Deng, R. Matheson, J. Lei, C. LeGuern, J. Markmann

7:00pm-8:00pm: Dynamic Changes in Titer and Specificity Autoantibodies in Chronic Bm12 to B/6 Kidney Rejection

I. Sayin¹, D. Yin¹, D. Ghosh², M. Clark², A. Chong¹

7:00pm-8:00pm: Fcγ Receptor-Positive Cells Play a Critical Role in Rejection of Allogeneic Bone Marrow Cells Mediated by Anti-Donor Antibodies

H. Xu¹, Y. Huang¹, H. Xu²

7:00pm-8:00pm: High Dimensional Analysis of IL-10-Producing Human B Cells and Their Characterization in Operationally Tolerant Transplant Recipients

M. C. Glass, D. Glass, J. Oliveria, B. Mbiribindi, C. Esquivel, S. M. Krams, S. C. Bendall, O. M. Martinez

7:00pm-8:00pm: Immunogenicity of a Quadrivalent Human Papillomavirus Vaccine in Pediatric Kidney and Liver Transplant Recipients

T. Kitano¹, K. Schwartz², M. Abdulnoor¹, H. Garfield³, N. K. Booran¹, Y. Avitzur¹, C. Teoh¹, D. Hebert⁴, U. Allen³

7:00pm-8:00pm: Influence of Regulatory B Cells on B Cells

Q. Fu¹, K. M. Lee², K. Deng², D. Agarwal¹, R. Matheson³, T. Press¹, J. Lei⁴, H. Yang⁵, C. LeGuern², S. Deng⁵, J. F. Markmann²

7:00pm-8:00pm: Marginal Zone Phenotype B Cells Are Required for Formation of Donor-Specific IgG After Allogeneic Sensitization

M. A. Kallarakal, G. Cohen, S. M. Krummey

7:00pm-8:00pm: Natural Antibodies Are Associated With Rejection And Long-term Renal Allograft Loss In A Multi-center International Cohort

S. B. See¹, X. Yang², C. Burger³, B. Lamarthée⁴, R. Snanoudj⁵, R. Shihab¹, D. S. Tsapepas⁶, P. Roy¹, S. Larivière-Beaudoin⁷, K. Hamelin⁷, A. Mendoza Rojas⁸, N. M. van Besouw⁸, A. Bartosic⁹, N. Daniel⁹, E. R. Vasilescu¹⁰, S. Mohan¹¹, D. Cohen¹¹, L. Ratner¹¹, C. C. Baan⁸, J. S. Bromberg⁹, H. Cardinal⁷, D. Anglicheau³, Y. Sun², E. Zorn¹

7:00pm-8:00pm: Optimal Development and Effector Function of Antibody-Suppressor CXCR5⁺CD8⁺ T Cells Requires Host IFN-γ and CD4⁺ T Cells

J. Zimmerer, S. Chaudhari, M. Hart, J. Han, K. Koneru, G. Bumgardner

7:00pm-8:00pm: Specificity and Avidity of Donor MHC-Specific B Cells in Naive, Rejecting and Tolerant Mice

I. Sayin¹, S. Khiew², D. Yin¹, P. Sage³, C. B. Cavazzoni³, R. King⁴, A. Chong¹

7:00pm-8:00pm: TNFRSF13B Genotype Determines the Properties of Donor-Specific B Cells

M. Cascalho¹, M. Garcia de Mattos Barbosa¹, T. Pasieka¹, E. Farkash², R. Sung³, M. Doshi⁴, J. Platt⁴