2022 American Transplant Congress » Antigen Presentation and Costimulation

3:30pm-3:40pm

Local Cognate Antigen in Kidney Allografts Promotes Tissue Resident Memory T Cell Maintenance

R. Tieu¹, Q. Zeng¹, D. Zhao¹, P. Manandhar², A. Williams¹, K. Abou-Daya¹, L. Kane², W. Shlomchik¹, M. Oberbarnscheidt¹, F. Lakkis¹

3:40pm-3:50pm

Lymphotoxin Beta Receptor Classical NFkB Signaling in Lymphatic Endothelial Cells Drives Treg Tissue Stability

V. Saxena¹, W. Piao¹, L. Li¹, M. W. Shirkey¹, R. Lakhan¹, S. Walden², K. L. Hippen², B. Blazar², J. S. Bromberg¹

3:50pm-4:00pm

P2X7R Signaling Controls Exosome Release by Macrophages and Donor MHC Cross-Dressing After Skin Transplantation

H. H. Lancia¹, N. Carnel², A. G. Lellouch¹, C. Cetrulo¹, G. Benichou²

4:00pm-4:10pm

Detection of Alloreactive CD8+ T Cell Responses and the Immunopeptidome That Elicits Their Activation

A. B. Morris, X. Zhang, E. V. Peek, A. Hadley, C. Larsen

4:10pm-4:20pm

T Cell-Specific CEACAM1 Alleviates Posttransplant Liver Injury via TIM-3 Inhibitory Regulation

H. Kojima, H. Hirao, K. Kadono, T. Ito, K. J. Dery, F. Kaldas, J. Kupiec-Weglinski

4:20pm-4:30pm

Perioperative IL-6 Blockade Promotes Intra-Graft Regulation and Prevents Costimulation-Blockade Resistant Rejection

M. Muckenhuber¹, K. Mengrelis¹, A. M. Weijler¹, V. Kainz¹, R. Steiner¹, H. Regele², T. Wekerle¹

4:30pm-4:40pm

IL-15 Signaling is Required for the Maintenance of Tissue Resident Memory T Cells in Chronic Allograft Rejection

R. Tieu¹, Q. Zeng¹, D. Zhao¹, A. Williams¹, J. Yun Tso², F. Lakkis¹, J. Yun Tso²

4:40pm-4:50pm

Absence of DAP12 Expression by Donor Liver-Derived Dendritic Cells Enhances Their Contact with T Cells in Host Secondary Lymphoid Tissue: Implications for Abrogation of MHC-mismatched Liver Transplant Tolerance in Mice

R. Nakano, A. Perez Gutierrez, G. Camirand, D. A. Geller, A. W. Thomson

4:50pm-5:00pm

Aquaporin 4 is a Mediator of Essential Dendritic Cell Functions

M. Nicosia¹, A. M. Beavers¹, Y. Yamamoto¹, T. Thompson², T. Zindrick², A. Valujskikh¹