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  • 2022 American Transplant Congress

    The Development of a Scientific Registry of Transplant Recipients Data Query Tool: A Human-Centered Design Process

    C. Schaffhausen1, A. Hart2, C. S. Zinner3, A. K. Israni2, J. Snyder1

    1Hennepin Healthcare Research Institute, Minneapolis, MN, 2Hennepin Healthcare (HHS) / University of Minnesota (UMN), Minneapolis, MN, 3Accenture Federal Services, Washington, DC

    *Purpose: The Scientific Registry of Transplant Recipients (SRTR) provides national transplant data in various forms, including the OPTN/SRTR Annual Data Report (ADR). The ADR includes…
  • 2022 American Transplant Congress

    Baseline Findings from the UREAACT Trial to Improve Medication Adherence in Youth with Kidney Transplants

    S. Amaral1, P. Kwong2, J. Zhu2, R. George3, N. Rodig4, B. Warady5, J. Smith6, A. Bobrowski7, D. Matossian8, N. Zelikovsky9, L. Schwartz1, P. Reese2, R. Goldfarb Terry1, J. Reason2, A. Chung1, S. Furth1

    1CHOP, Phila, PA, 2UPenn, Phila, PA, 3CHOA, Atlanta, GA, 4Boston Children's, Boston, MA, 5Children's Mercy, Kansas City, MO, 6Seattle Children's, Seattle, WA, 7Cleveland Clinic, Cleveland, OH, 8Lurie Children's, Chicago, IL, 9LaSalle Univ, Phila, PA

    *Purpose: This abstract describes the design and baseline characteristics of participants in the U-REAACT trial, a study to improve medication adherence in youth with kidney…
  • 2022 American Transplant Congress

    A Dose Dependent Effect of Varying Tacrolimus Concentrations on Cytomegalovirus Viral Specific T Cell Interferon Gamma Expression

    H. L. Kleiboeker1, M. R. Jorgenson1, R. O. Meyers2, O. Ganz2, S. Parajuli3, J. Galipeau4

    1Pharmacy, University of Wisconsin Hospital and Clinics, Madison, WI, 2Program for Advanced Cell Therapy, University of Wisconsin Hospital and Clinics and School of Medicine and Public Health, Madison, WI, 3Medicine, Division of Nephrology, University of Wisconsin School of Medicine and Public Health, Madison, WI, 4Medicine, Division of Hematology and Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI

    *Purpose: Tacrolimus, considered the backbone of transplant immunosuppression, is associated with increased risk of viral infections, including cytomegalovirus (CMV), due to its potent inhibitory effect…
  • 2022 American Transplant Congress

    Incidence of Biliary Complications at the Beginning of the Academic Year in an Academic Transplant Program

    M. E. Tobon Lascano, C. J. Simon, M. E. Akoad, J. Kim, M. Simpson, Y. Cheah

    Transplant, Lahey Clinic, Burlington, MA

    *Purpose: Surgery learning is based on a master-apprentice model, a learning curve is essential to measure the acquisition and improvement of surgical skills without compromising…
  • 2022 American Transplant Congress

    Therapeutic Drug Monitoring of Crushed Posaconazole Delayed Release Tablets in Lung Transplant Patients

    S. Sial, K. Cunningham, J. Moore, C. Dagostino, K. Lang, C. Kane

    Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Lung transplant patients are at an increased risk for invasive fungal infections and often require prophylaxis post-transplant, routinely including posaconazole at our institution. These…
  • 2022 American Transplant Congress

    Impact and Consequences of Recipient Gastroduodenal Artery (GDA) Ligation Prior to Hepatic Artery (HA) Anastomosis During Orthotopic Liver Transplantation (OLT)

    A. Kumar, D. Gerber, C. Desai

    Abdominal Transplant Surgery, UNC School of Medicine, Chapel Hill, NC

    *Purpose: The recipient GDA is often ligated before the HA anastomosis during OLT either to gain mobility, length on recipient HA and with hypothesis that…
  • 2022 American Transplant Congress

    Evaluation of Different Initial Tacrolimus Dosing Regimens in Pediatric Post-Liver Transplantation

    A. F. Alghanem1, A. Alsmari1, H. Joharji2

    1Pharmaceutical Care, King Abdulaziz Medical City, Riyadh, Saudi Arabia, 2Pharmaceutical Care, King Faisal Specialized Hospital and Research Center, Riyadh, Saudi Arabia

    *Purpose: Tacrolimus is an immunosuppressant used in post-liver transplantation, has wide pharmacokinetic variability, particularly in pediatric patients. Therefore, this study aimed to evaluate different weight-based…
  • 2022 American Transplant Congress

    Characterization of GZMB+ Bregs Transcriptome and Their Impact on Target Cells in Single-Cell RNA-seq

    N. Sailliet, H. Le Mai, A. Dupuy, F. Cynthia, M. Chesneau, J. Poschmann, R. Danger, S. Brouard

    CRTI- INSERM UMR 1064, Nantes, France

    *Purpose: During the inflammatory process, the immune system capacity to regulate itself is mandatory to balance effector positive feedback, avoid allergies and autoimmunity. Different subsets…
  • 2022 American Transplant Congress

    Development of a Comprehensive Banff Automation System for Kidney Allograft Precision Diagnostics

    D. Yoo1, J. Gueguen1, G. Divard1, M. Raynaud1, V. Goutaudier1, M. Rabant1, M. Haas2, M. Mengel3, O. Aubert1, A. Loupy1

    1Paris Transplant Group, Paris, France, 2Cedars-Sinai Medical Center, Dept. of Pathology, West Hollywood, CA, 3University of Alberta, Edmonton, AB, Canada

    *Purpose: Since 1991, the Banff classification has been the gold standard for kidney allograft rejection diagnostics. However, with time, the classification has become complex with…
  • 2022 American Transplant Congress

    Development of a Culturally Sensitive Chatbot to Inform Living Donor Candidates of African Ancestry About Apol1 Genetic Testing

    E. J. Gordon1, P. Waite2, J. Gacki-Smith2, D. Duquette3, A. Agrawal1, J. Friedewald1, S. Savage4, E. Simmons5, M. Cooper6, A. Gilbert6, C. Wicklund7

    1Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Center for Health Services and Outcomes Research, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 4Invitae, Inc, San Francisco, CA, 5Invitae, San Francisco, CA, 6Surgery, Georgetown University Medical Center, Washington, DC, DC, 7Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL

    *Purpose: Living kidney donor candidates of African ancestry are increasingly asked to undergo Apolipoprotein L1 (APOL1) genetic testing to better understand their risk of kidney…
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