2015 American Transplant Congress
Phenotypic Personalized Medicine: Mechanism-Independent Convergence Into Target Serum Tacrolimus Levels for Optimized Liver Transplant Immunosuppression
PURPOSE:Immunosuppressive drugs such as tacrolimus have narrow therapeutic ranges and their dosing variability necessitates intensive drug monitoring. This study aimed to use Feedback System Control…2015 American Transplant Congress
Tolerant Kidney Transplant Patients Display B Cells With Regulatory Properties
Whereas a B cell transcriptional profile has been recorded for operationally tolerant kidney graft patients, the role that B cells may play in this process…2013 American Transplant Congress
Improving Value after Pediatric Liver Transplant: Discharge Practices of High-Performing Centers
We sought to improve value (outcomes/cost) for the initial hospitalization after pediatric liver transplantation (LT) by identifying variation in length of stay (LOS), a highly…2013 American Transplant Congress
Comprehensive Analyses of Inhibitory Effects of the mTOR Inhibitor Everolimus on the Differentiation into Subsets of Human T-Helper Cells and B Cells
Hiroshima University, Hiroshima, Japan
[Aim] Although the various potential benefits of everolimus over other immunosuppressants in organ transplantation have been described, the precise sensitivity of this drug to differentiation…2013 American Transplant Congress
Mesenchymal Stromal Cells Promote Bowel Regeneration after Intestinal Transplantation: Myth to Mucosa
Aim: To report the first case of use of mesenchymal stromal cells (MSCs) to promote mucosal regeneration in an isolated intestinal transplant recipient who had…2013 American Transplant Congress
Subtle Deregulation of Circadian Rhythm in Mice with Partial A20 Knockdown Severely Impacts Lipid Metabolism Following Partial Hepatectomy Causing Defective Regeneration and Increased Lethality
Overexpression of A20 promotes liver regeneration (LR), but contribution of physiologic A20 to LR remains unclear. We performed 2/3 partial hepatectomy (PH) in A20 heterozygous…2013 American Transplant Congress
Impact of Transplant Guardian Angels on the Patient Experience, The
Starzl Transplantation Institute, UPMC, Pittsburgh, PA
Background: A tertiary care facility can be overwhelming to patients and their families when they are called in for transplant. The off-hours nature and lack…2013 American Transplant Congress
Fish Oil Diet Overcomes Genetic Predisposition Restoring Hepatocyte Proliferation in Livers of A20 Heterozygous Mice Following Partial Hepatectomy
Surgery, Beth Israel Deaconess Medical Center - HMS, Boston, MA
Increased free fatty acids (FA) metabolism following partial hepatectomy (PH) is required to meet energy demands of liver regeneration (LR). Impact of dietary lipid intake…2013 American Transplant Congress
Axin2/β-Catenin/Notch1 Sigaling Regulates Innate Immunity in Mouse Model of Liver Ischemia/Reperfusion Injury
Dumont-UCLA Transplant Ctr, Dept of Surgery, UCLA School of Medicine, Los Angeles, CA
Background: Axin2 is a multiple function protein involved in many biological pathways, and its overexpression might regulate Β-catenin activity. The Notch signaling is known to…2013 American Transplant Congress
NAFLD and Dietary Fatty Acid Composition: The Good, the Bad and the Ugly
Medical University of South Carolina, Charleston, SC
Background: Nonalcoholic steatohepatitis (NASH) is predicted to become the primary cause of end-stage liver disease necessitating transplantation. However, recurrence of NASH and fibrosis post-transplantation is…
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