ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Safety Issues Identified by Proactive Liver Transplant Safety Debriefing

    D. Ladner, T. Berzins, L. Pomfret, M. Simpson, R. Brown, R. Fisher, A. Daud, T. Strenski, L. McElroy, J. Holl, D. Woods

    Northwestern University, Chicago; Lahey Clinic, Boston; Columbia University, New York; Virginia Commonwealth University, Richmond

    BACKGROUND: Transplantation and, in particular, living donor liver transplantation (LDLT), involves complex systems and process of care that are particularly susceptible to medical errors and…
  • 2013 American Transplant Congress

    NKp46 Expression Accelerates the Formation of the NK Cell Lytic Immune Synapse

    U. Hadad, T. Thauland, M. Butte, S. Krams

    Div. of Abdominal Transplantation/Dept. of Surgery, Stanford University, Stanford, CA; Dept. of Pediatrics, Stanford University, Stanford, CA; Dept. of Microbiology and Immunology, Ben-Gurion University of the Negev, Beer Sheva, Israel

    Natural killer cells play an important role in first-line defense against tumor and virus-infected cells. Studies suggest NK cells have a dichotomous role in transplantation…
  • 2013 American Transplant Congress

    Targeting Inositol-Requiring Enzyme 1α in Prevention of Donor Specific Antibody (DSA) Mediated Rejection

    J. Ye, Q. Qiu, J. Wang, D. Fang, Z. Zhang

    Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago; Department of Pathology, Feinberg School of Medicine, Chicago

    Introduction: Inositol-requiring enzyme 1Α (IRE1Α), an endoplasmic reticulum-located transmembrane protein kinase, is the activator of transcription factor X-box-binding protein 1 (XBP1) that is required for…
  • 2013 American Transplant Congress

    Simultaneous Pancreas-Kidney Transplantation in Patients with End-Stage Nephropathy Due to Type 2 Diabetes Mellitus Gives Better Results When Compared to Kidney Transplants Alone

    C. Margreiter, T. Resch, R. Oberhuber, F. Aigner, R. Sucher, R. Margreiter, J. Pratschke, R. Öllinger

    Department of Visceral-, Transplant- and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria

    Objective: SPK in type 2 diabetes (T2DM) is performed by a few centers in selected patients. The purpose of the study was to compare patient…
  • 2013 American Transplant Congress

    Modified Technique of Auxiliary Partial Liver Transplantation in Rat for the Study of Liver Regeneration and Tissue Engineering In Vivo, A

    Y. Wu, J. Wang, J. Ye, M. Abecassis, J. Wertheim, Z. Zhang

    Comprehensive Transplant Center and Department of SurgeryDepartment of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL

    Background:Organ engineering and regenerative medicine using decellularized liver scaffolds offer a promising solution to organ shortage. Auxiliary partial liver transplantation (APLT) in rat is considered…
  • 2013 American Transplant Congress

    Different Effects of mTOR Inhibitor VS CN Inhibitor on Human B Cells Proliferations and Activation Markers

    G. La Monica, L. Xu, G. Chalasani, L. Gallon

    Nephrology/Medicine, Northwestern University, Chicago, IL; Renal-Electrolyte/Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA

    Background: Humoral immunity is increasingly recognized as an important factor in promoting transplant rejection. However, it is not well known how commonly used immunosuppressive drugs…
  • 2013 American Transplant Congress

    CD39 Regulates the Activation of Liver DC and Protects Against Liver Transplant Ischemic Reperfusion Injury

    O. Yoshida, S. Kimura, S. Robson, N. Murase, A. Thomson

    Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA; Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA

    Background: ATP is an energy source stored in the cell cytosol. Once released into extracellular(e) space as a result of cell injury/death, eATP acts in…
  • 2013 American Transplant Congress

    Effects of Viral Infection on Chronic Anti-Mediated Rejection, The

    B. Oh, R. Ruhil, O. Bulut, J. Kwun, A. Kirk, S. Knechtle, N. Iwakoshi

    Emory Transplant Center, Atlanta

    [Background] Despite a 50% decline in acute rejection over the past 10 years, antibody-mediated injury has been identified as perhaps the leading cause of chronic…
  • 2013 American Transplant Congress

    Does Secondary Prophylaxis Prevent CMV Relapse Following Treatment of CMV Disease in Kidney Transplant Recipients?

    T. Sullivan, A. Brodginski, S. Huprikar

    Division of Infectious Diseases, Mount Sinai Hospital, New York, NY

    BackgroundAlthough many centers use secondary prophylaxis to prevent relapse following the treatment of CMV disease in kidney transplant recipients (KTR), there is limited data to…
  • 2013 American Transplant Congress

    Novel Model of Antibody Mediated Rejection of Kidney Allografts in Rats, A

    G. Huang, N. Wilson, S. Reese, L. Jacobson, W. Baldwin III, W. Zhong, A. Djamali

    Department of Surgery, University of Wisconsin, Madison, WI; Department of Medicine, Division of Nephrology, University of Wisconsin, Madison, WI; Department of Pathology, University of Wisconsin, Madison, WI; Immunology, The Cleveland Clinic Foundation, Cleveland, OH

    We have developed a new experimental model of acute ABMR, in which complete MHC mismatched kidneys are transplanted from Brown Norway rats (RT1n) into Lewis…
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