- 2013 American Transplant Congress - Predictors of Clostridium Difficile Infection in Liver Transplant Recipients: A 10 Year Single-Center Cohort Study- Transplant Institute, Henry Ford Hospital, Detroit, MI Background: Clostridium difficile infection (CDI) is a common cause of morbidity and is associated with increased in-hospital mortality among solid organ transplant recipients. The incidence…
- 2013 American Transplant Congress - Prolonged Cold Ischemia Impairs Outcome in Recipients of Donation after Cardiac Death (DCD) Kidney Transplants Despite Machine Perfusion- Miami Transplant Institute, University of Miami Miller School of Medicine, Miami Introduction: The impact of prolonged cold ischemia time (CIT) on kidney grafts donated after circulatory death (DCD) remains unclear when grafts were preserved by hypothermic…
- 2013 American Transplant Congress - Associations between Clinical, Biochemical Indicators and Anthropometric Measurements with Arterial Stiffness in Renal Transplantation PatientsPurpose: Arterial stiffness is an independent predictor for cardiovascular mortality. In end stage renal disease cardiovascular risk factors such as age, hypertension and diabetes mellitus…
- 2013 American Transplant Congress - Impact of Prospective Monitoring for Donor Specific Antibodies on Renal Transplant Outcomes with Alemtuzumab Induction- MultiOrgan Transplant Program, William Beaumont Hospital, Royal Oak, MI Alemtuzumab (AL) induction has been associated with an excess of antibody-mediated rejection (AMR). We initiated a steroid-free AL protocol in August 2009 with prospective monitoring…
- 2013 American Transplant Congress - Multicenter Banff Fibrosis Trial: Comparing Visual Assessment of Interstitial Fibrosis in Kidney Biopsies to Computer-Based Image Analysis and Organ Function, TheInterstitial fibrosis (IF) in renal biopsies is a valuable correlate for organ function, provides prognostic information and is a potential end point in trials.From 15…
- 2013 American Transplant Congress - D-MELD, a Powerful Instrument To Optimize Donor-2-Recipient Match. Differences between US and ItalyPrevious studies demonstrated in US and Italy that D-MELD can be an instrument to optimize donor-2-recipient match (D2Rm) in Liver Transplantation.To characterize prognostic power, peculiarities…
- 2013 American Transplant Congress - ATP-Competitive mTORC1 and 2 Inhibitors Are a Novel Class of Immunosuppressants That Suppress Allograft Rejection- Surgery, Starzl Transplant Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA Introduction: The mammalian Target of Rapamycin (mTOR) is the active catalytic subunit of two mTOR-containing complexes  mTOR complex (mTORC) 1 and mTORC2. mTORC1 is…
- 2013 American Transplant Congress - MicroRNA Profiling in Ischemia Reperfusion Injury Performed by Next Generation Sequencing in Human Renal TransplantationObjectives: In a variety of (patho-) physiological situations microRNAs, small noncoding RNA fragments of 20-24 bp of length, display import post-transcriptional gene regulators. Current pathology…
- 2013 American Transplant Congress - Safety Issues Identified by Proactive Liver Transplant Safety DebriefingBACKGROUND: Transplantation and, in particular, living donor liver transplantation (LDLT), involves complex systems and process of care that are particularly susceptible to medical errors and…
- 2013 American Transplant Congress - NKp46 Expression Accelerates the Formation of the NK Cell Lytic Immune SynapseNatural killer cells play an important role in first-line defense against tumor and virus-infected cells. Studies suggest NK cells have a dichotomous role in transplantation…
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