- 2013 American Transplant Congress - Clinical Outcomes of Paired Kidney Exchange for Highly Sensitized Renal Transplant RecipientsPurpose: A local multicenter paired kidney exchange (PKE) was employed to facilitate identification of compatible donors for highly-sensitized recipients.Methods: Virtual crossmatching was used to identify…
- 2013 American Transplant Congress - Predictors of Clostridium Difficile Infection in Liver Transplant Recipients: A 10 Year Single-Center Cohort Study- Transplant Institute, Henry Ford Hospital, Detroit, MI Background: Clostridium difficile infection (CDI) is a common cause of morbidity and is associated with increased in-hospital mortality among solid organ transplant recipients. The incidence…
- 2013 American Transplant Congress - Prolonged Cold Ischemia Impairs Outcome in Recipients of Donation after Cardiac Death (DCD) Kidney Transplants Despite Machine Perfusion- Miami Transplant Institute, University of Miami Miller School of Medicine, Miami Introduction: The impact of prolonged cold ischemia time (CIT) on kidney grafts donated after circulatory death (DCD) remains unclear when grafts were preserved by hypothermic…
- 2013 American Transplant Congress - Donor Brain Death Results in Differentially Modulated Immune Activation in Solid OrgansDonor brain death (BD) and its pathophysiological changes have been shown to influence graft quality, therefore accelerating the immune response post transplantation. However, detailed information…
- 2013 American Transplant Congress - Impact of Prospective Monitoring for Donor Specific Antibodies on Renal Transplant Outcomes with Alemtuzumab Induction- MultiOrgan Transplant Program, William Beaumont Hospital, Royal Oak, MI Alemtuzumab (AL) induction has been associated with an excess of antibody-mediated rejection (AMR). We initiated a steroid-free AL protocol in August 2009 with prospective monitoring…
- 2013 American Transplant Congress - Multicenter Banff Fibrosis Trial: Comparing Visual Assessment of Interstitial Fibrosis in Kidney Biopsies to Computer-Based Image Analysis and Organ Function, TheInterstitial fibrosis (IF) in renal biopsies is a valuable correlate for organ function, provides prognostic information and is a potential end point in trials.From 15…
- 2013 American Transplant Congress - Associations between Clinical, Biochemical Indicators and Anthropometric Measurements with Arterial Stiffness in Renal Transplantation PatientsPurpose: Arterial stiffness is an independent predictor for cardiovascular mortality. In end stage renal disease cardiovascular risk factors such as age, hypertension and diabetes mellitus…
- 2013 American Transplant Congress - ATP-Competitive mTORC1 and 2 Inhibitors Are a Novel Class of Immunosuppressants That Suppress Allograft Rejection- Surgery, Starzl Transplant Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA Introduction: The mammalian Target of Rapamycin (mTOR) is the active catalytic subunit of two mTOR-containing complexes  mTOR complex (mTORC) 1 and mTORC2. mTORC1 is…
- 2013 American Transplant Congress - MicroRNA Profiling in Ischemia Reperfusion Injury Performed by Next Generation Sequencing in Human Renal TransplantationObjectives: In a variety of (patho-) physiological situations microRNAs, small noncoding RNA fragments of 20-24 bp of length, display import post-transcriptional gene regulators. Current pathology…
- 2013 American Transplant Congress - D-MELD, a Powerful Instrument To Optimize Donor-2-Recipient Match. Differences between US and ItalyPrevious studies demonstrated in US and Italy that D-MELD can be an instrument to optimize donor-2-recipient match (D2Rm) in Liver Transplantation.To characterize prognostic power, peculiarities…
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