2013 American Transplant Congress
Pancreas Transplantation: Personal Factors Associated with Good and Poor Post-Transplant Adaptive Response
Notable differences in patient adaptation after pancreas transplant cause some to thrive and return to independent living, while others struggle with emotional and social problems.…2013 American Transplant Congress
Evaluation of Cystic Growth in ADPKD Renal Transplant Recipients Following Conversion to an mTOR Inhibitor
Univ of Toledo Medical Center, Toledo, OH
Introduction: Previous animal studies of ADPKD suggest sirolimus reduces kidney volume, cyst size and density, and restores overall kidney function as measured by BUN and…2013 American Transplant Congress
When Drugs Run Out: Tolerability of Mycophenolate Mofetil and Azathioprine in Lung Transplant Recipients over the Age of Sixty
Pharmacy, Emory University Hospital, Atlanta, NC; Pharmacy, Duke University Hospital, Durham, NC
Triple-drug therapy with tacrolimus, azathioprine (AZA), and prednisone is the standard immunosuppression protocol for lung transplant at Duke University Hospital (DUH). The recent shortage of…2013 American Transplant Congress
Graft Loss Rates after Donation after Cardiac Death (DCD) Liver Donation Are Severely Underestimated
Introduction: Organs from DCD donors, particularly livers, have been shown to have outcomes that are inferior to those from donation after brain death (DBD) donors…2013 American Transplant Congress
Complement Blockade Prevents Delayed Graft Function in a Non-Human Primate Model of Kidney Allo-Transplantation
Surgery, University of Wisconsin- Madison, Madison, WI; Pharming Group NV, Leiden, Netherlands
Brain-death (BD) induces an innate immune response that increases the risk of delayed graft function (DGF) and leads to reduced graft survival and increased immunogenicity…2013 American Transplant Congress
Incidence of CMV Infection Comparing Two Antiviral Preventative Strategies after Liver Transplantation
Pharmacy, Barnes-Jewish Hospital, St. Louis, MO; Surgery, Washington University, St. Louis, MO
Purpose: CMV remains a common complication of liver transplantation, and its direct and indirect effects contribute greatly to the morbidity and mortality in this patient…2013 American Transplant Congress
Accelerated Hepatic Fibrosis after Renal Transplantation: Long-Term Outcomes in HCV+ Patients
Surgery, Division of Transplantation, University of Maryland, Baltimore, MD
Introduction: It has been demonstrated that hepatitis C+ (HCV+) patients with renal failure benefit from kidney transplantation despite having decreased graft survival compared to HCV-…2013 American Transplant Congress
Alemtuzumab Induction and Steroid Free Maintenance in Predominately African American Renal Allograft Recipients
Surgery, Washington Hospital Center, Washington, DC
Introduction: Alemtuzumab (C-1H) has been used off label in solid organ transplantation as an induction agent. It promotes long lasting lymphocyte depletion allowing for reduced…2013 American Transplant Congress
Liver B Cells Exhibit Pro-Inflammatory Activity, Secrete Less IL-10, and Are More Potent Inducers of Hepatic DC Maturation Than Those from Secondary Lymphoid Tissue
Surgery, University of Pittsburgh, Pittsburgh, PA
Introduction: B cells perform various immunological functions that include Ab production, Ag presentation, secretion of multiple cytokines, and regulation of immune responses, mainly via secretion…2013 American Transplant Congress
Monocyte Affinity for Donor Antigen Predicts Acute Cellular Rejection (ACR) after Intestinal or Liver Transplantation (ITx, LTx)
Background: Rejection-prone intestine allografts demonstrate CD14+monocyte-rich infiltrates immediately after reperfusion, suggesting that monocytes are capable of allorecognition akin to adaptive immunity. Purpose: To evaluate whether…
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