- 2013 American Transplant Congress - Targeting of mTORC2 in DC Elicits an Enhanced Pro-Inflammatory Profile and Th17 AlloresponseMammalian target of rapamycin (mTOR) is an important, yet poorly understood integrative kinase that regulates immune cell function. mTOR functions in two independent complexes,- mTOR…
- 2013 American Transplant Congress - Pronounced Impact of Community Risk Factors on Pre-Transplant Kidney Candidate Processes and OutcomesIntroductionThere are many potential factors which are associated with patient outcomes beyond traditional clinical and donor characteristics.MethodsWe merged national SRTR data with data aggregated from…
- 2013 American Transplant Congress - Fish Oil Diet Overcomes Genetic Predisposition Restoring Hepatocyte Proliferation in Livers of A20 Heterozygous Mice Following Partial Hepatectomy- Surgery, Beth Israel Deaconess Medical Center - HMS, Boston, MA Increased free fatty acids (FA) metabolism following partial hepatectomy (PH) is required to meet energy demands of liver regeneration (LR). Impact of dietary lipid intake…
- 2013 American Transplant Congress - French Uncontrolled Donors after Circulatory Arrest (Udcd) Program for Kidney Transplantation: Procurement Procedure Efficiency and 3-Month Survival ResultsThe national protocol for the uDCD program restricts the no flow period to <30 min and the total warm ischemia time (WIT) to <150 min.…
- 2013 American Transplant Congress - Network Meta-Analysis of Immunosuppressant Regimens in Renal Preservation Following Liver Transplant, ABackground: Long-term exposure to Calcineurin-Inhibitors (CNIs) has been associated with impaired renal function.Objective: To obtain parameter estimates of the relative renal safety of commonly used…
- 2013 American Transplant Congress - Interim Analysis of a Double-Blinded Placebo Controlled Trial of IVIG v. IVIG + Rituximab for Desensitization of Highly-HLA Sensitized (PRA >80%) (HS) Deceased Donor (DD) CandidatesINTRODUCTION: Desensitization protocols (DES) for HS patients are primarily aimed at living-donor recipients. The efficacy of various DES is not established, especially for DD recipients.…
- 2013 American Transplant Congress - Safety and Efficacy of the Levonorgestrel-Releasing Intrauterine System in Transplant PatientsIntroduction: The levonorgestrel intrauterine contraceptive system (LNG-IUS) is safe and effective for contraception, dysmenorrhea, and treatment of heavy menstrual bleeding. Safety and efficacy has been…
- 2013 American Transplant Congress - Kidney Transplant Volume and Outcomes Trends in the Era Surrounding Initiation of the Medicare Conditions of ParticipationBackground: In mid-2007, the Centers for Medicare and Medicaid Services (CMS) implemented Conditions of Participation for organ transplant programs, under which programs not attaining specified…
- 2013 American Transplant Congress - NK Depletion Reduces Murine Cytomegalovirus Induced Renal Allograft Injury Despite Increased Viral Loads in a Murine Transplant ModelPURPOSE: NK cell activation is induced by viral infection and has been associated with renal allograft injury in clinical populations and animal models, so this…
- 2013 American Transplant Congress - How Do Anhepatic Patients Fair? A Single-Center Experience of Thirteen Patients Requiring Total Hepatectomy and Portocaval Shunting for Severe Hepatic Dysfunction- Department of Surgery, The Dumont-UCLA Liver Transplant Center, Los Angeles, CA BACKGROUND/AIMS:Total hepatectomy with portocaval shunting (TH-PS) is a last-resort in patients with severe acute liver dysfunction awaiting liver transplantation (LT). The anhepatic state portends dismal…
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