ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Network Meta-Analysis of Immunosuppressant Regimens in Renal Preservation Following Liver Transplant, A

    F. Bianic, A. Davie, R. Campbell, J. Ricci, C. Escrig, S. Gokhale, J. Lake

    OptumInsight, Nanterre, France; OptumInsight, Uxbridge, United Kingdom; Wellmera AG, Basel, Switzerland; Novartis Pharma AG, Basel, Switzerland; Novartis Healthcare Pvt. Ltd., Hyderabad, India; University of Minnesota, MN

    Background: Long-term exposure to Calcineurin-Inhibitors (CNIs) has been associated with impaired renal function.Objective: To obtain parameter estimates of the relative renal safety of commonly used…
  • 2013 American Transplant Congress

    Interim Analysis of a Double-Blinded Placebo Controlled Trial of IVIG v. IVIG + Rituximab for Desensitization of Highly-HLA Sensitized (PRA >80%) (HS) Deceased Donor (DD) Candidates

    A. Vo, J. Choi, M. Lukovsky, M. Toyoda, S. Ge, J. Kahwaji, A. Peng, R. Villicana, R. Najjar, S. Jordan

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; Transplant Immunology Laboratory, Cedars-Sinai Medical Center

    INTRODUCTION: Desensitization protocols (DES) for HS patients are primarily aimed at living-donor recipients. The efficacy of various DES is not established, especially for DD recipients.…
  • 2013 American Transplant Congress

    Safety and Efficacy of the Levonorgestrel-Releasing Intrauterine System in Transplant Patients

    T. Nizamic, A. Amies Oelschlager, K. Debiec, J. Smith, E. Micks, S. Prager

    Obstetrics and Gynecology, University of Washington, Seattle, WA; Pediatric and Adolescent Gynecology, Seattle Children's Hospital, Seattle, WA

    Introduction: The levonorgestrel intrauterine contraceptive system (LNG-IUS) is safe and effective for contraception, dysmenorrhea, and treatment of heavy menstrual bleeding. Safety and efficacy has been…
  • 2013 American Transplant Congress

    Kidney Transplant Volume and Outcomes Trends in the Era Surrounding Initiation of the Medicare Conditions of Participation

    S. White, D. Zinsser, M. Paul, G. Levine, T. Shearon, V. Ashby, J. Magee, A. Leichtman

    KECC, University of Michigan, Ann Arbor; Dept of Medicine, University of Michigan, Ann Arbor; Dept of Surgery, University of Michigan, Ann Arbor

    Background: In mid-2007, the Centers for Medicare and Medicaid Services (CMS) implemented Conditions of Participation for organ transplant programs, under which programs not attaining specified…
  • 2013 American Transplant Congress

    NK Depletion Reduces Murine Cytomegalovirus Induced Renal Allograft Injury Despite Increased Viral Loads in a Murine Transplant Model

    M. Shimamura, L. Guo, J. George, T. Schoeb, W. Britt

    Pediatric Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL; Cardiovascular/Thoracic Surgery, University of Alabama at Birmingham, Birmingham, AL; Genetics, University of Alabama at Birmingham, Birmingham, AL

    PURPOSE: NK cell activation is induced by viral infection and has been associated with renal allograft injury in clinical populations and animal models, so this…
  • 2013 American Transplant Congress

    How Do Anhepatic Patients Fair? A Single-Center Experience of Thirteen Patients Requiring Total Hepatectomy and Portocaval Shunting for Severe Hepatic Dysfunction

    K. Lau, A. Zarrinpar, V. Agopian, F. Kaldas, D. Farmer, R. Busuttil

    Department of Surgery, The Dumont-UCLA Liver Transplant Center, Los Angeles, CA

    BACKGROUND/AIMS:Total hepatectomy with portocaval shunting (TH-PS) is a last-resort in patients with severe acute liver dysfunction awaiting liver transplantation (LT). The anhepatic state portends dismal…
  • 2013 American Transplant Congress

    Eculizumab (Anti-C5) for Treatment of Severe Antibody-Mediated Rejection (ABMR) and Recurrent C3 Glomerulonephritis in Renal Allografts: A Single Center Experience

    S. Jordan, J. Choi, R. Villicana, A. Peng, J. Kahwaji, R. Najjar, A. Vo

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA

    INTRODUCTION: ABMR is a severe form of allograft injury mediated, primarily, by antibody-induced complement activation. Complement activation through the alternate pathway may also result in…
  • 2013 American Transplant Congress

    Long-Term Impact of a Pancreas Graft on a Previously Transplanted Kidney

    A. Gruessner, R. Gruessner

    College of Public Health, University of Arizona, Tucson, AZ; Department of Surgery, University of Arizona, Tucson, AZ

    Introduction]: While pancreas after kidney (PAK) transplant allow for pre-emptive kidney transplant and reduced waiting times, there is concern that the additional ‘burden' of the…
  • 2013 American Transplant Congress

    Successful Transplantation of Kidney Allografts in Sensitized Rats Made Possible by Autologous Hematopoietic Stem Cell Transplantation (HSCT) and Fludarabine

    Y. Fu, R. Montgomery, Y. Wang, E. Fuchs, Z. Shen, G. Williams, Z. Sun

    Johns Hopkins University School of Medicine, Baltimore; Tianjin First Central Hospital and Tianjin Medical University, Tianjin, China

    We tested whether resetting the immune system with autologous HSC after preconditioning with Fludarabine improves kidney allograft survival in sensitized hosts.Methods: MHC mismatched DA (RT1Aa)…
  • 2013 American Transplant Congress

    Barriers for Seniors To Get Listed for Kidney Transplantation

    S. Bolourani, L. Lindquist, B. Lapin, D. Ladner

    Northwestern University Transplant Outcomes Research Collaborative (NUTORC), Comprehensive Transplant Center, Northwestern University, Chicago; Rosalind Franklin University School of Medicine and Science, Chicago Medical School, North Chicago; General Internal Medicine, Northwestern University, Chicago

    Introduction: Kidney transplant (KT) provides patients with improved survival rate and higher quality of life measures, and impose a significantly lower cost on Medicare when…
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