ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Pharmaceutical Quality and Bioequivalence Assessment of Generic Mycophenolate Mofetil Tablets

    W. Jiang, R. Lionberger, J. Li, Y. Peng, L. Yu

    Office of Generic Drugs, FDA, Rockville

    Purpose. Mycophenolate Mofetil (MMF) is the most used immunosuppressant in solid organ transplantation. Concerns have been raised about substitution between brand and generic MMF tablets.…
  • 2013 American Transplant Congress

    Behavioral Reference Points in Organ Utilization

    K. Schnier, V. Sadiraj, J. Cox, N. Turgeon

    Economics, Georgia State University, Atlanta, GA; Emory Transplant Center, Emory University, Atlanta, GA

    Background: Behavioral reference points partition preferences and define the regions over which an outcome is perceived as a “gain” or “loss.” Whether or not behavioral…
  • 2013 American Transplant Congress

    Banff Scoring in Early and Late Acute Cellular Rejection Predicts Graft Survival

    J. Krisl, R. Alloway, A. Shields, D. Witte, E. Woodle

    U of Cincinnati, Cincinnati, OH; Christ Hospital, Cincinnati, OH

    Acute rejection (AR) Banff grade (BG) correlates with long-term graft survival, however, previous validation studies did not account for rejection type (acute cellular rejection (ACR)/antibody…
  • 2013 American Transplant Congress

    Results of Early Corticosteroid Withdrawal under rATG Induction in Hepatitis C Positive Kidney Transplant Recipients: Inferior Yet Improved Outcomes

    M. Aull, J. Guerrero, C. Afaneh, D. Dadhania, J. McDermott, J. Kim, A. Watkins, S. Kapur

    NY-Presbyterian/Weill Cornell, New York, NY

    Hepatitis C virus (HCV) positive kidney transplant recipients face a significant risk of acute rejection (AR), graft loss, new onset diabetes mellitus (NODM), and mortality…
  • 2013 American Transplant Congress

    Depletion of Both Recipient and Donor Foxp3+ Cells Can Break Tolerance of Skin or Heart Allografts Induced by Mixed Chimerism in Mice

    K. Shinoda, T. Akiyoshi, C. Chase, E. Farkash, P. Russell, J. Madsen, R. Colvin

    Transplant Center, Massachusetts General Hospital, Boston, MA; Department of Pathology, Massachusetts General Hospital, Boston, MA

    Donor-specific transplant tolerance has been achieved by induction of mixed chimerism in both mice and humans and evidence for both deletion and regulation exists. To…
  • 2013 American Transplant Congress

    Infectious Disease Screening of Living Kidney and Liver Donors at a Large Transplant Center

    J. Kim, C. Freise, P. Chin-Hong

    Infectious Diseases, University of California, San Francisco, CA; Transplant Surgery, University of California, San Francisco, CA

    Background: Screening practices for infection in potential living kidney and liver donors have not been standardized among transplant centers despite rare but potentially life-threatening transmitted…
  • 2013 American Transplant Congress

    Is Micro-RNA-122 (miR-122) an Accurate Biomarker for Ischemia-Reperfusion Injury during Liver Transplantation?

    M. Hughes, S. Reddy, M. Brier, C. McClain, C. Jonsson

    Surgery, University of Louisville, Louisville, KY; Medicine, University of Louisville, Louisville, KY; Microbiology and Immunology, University of Louisville, Louisville, KY

    PURPOSE: Liver specific miR-122 has been shown to be potential biomarker for liver injury; however initial production of miR-122 during allograft reperfusion has not been…
  • 2013 American Transplant Congress

    Knowledge and Attitude of the Flemish Primary Care Physician towards Organ Donation and Transplantation

    L. Coucke, E. Snoeck, J. De Maeseneer, I. Haentjens, W. Peersman, X. Rogiers

    Department of Solid Organ Transplantation, Ghent University Hospital, Ghent, Belgium; Department of Family Medicine and Primary Health Care, Ghent University, Ghent, Belgium

    PURPOSE- Primary care physicians might play an important role in the acceptance of organ donation in the population. This would require both a positive attitude…
  • 2013 American Transplant Congress

    Significant Deficiencies in Postoperative Handoffs Revealed in a Comprehensive Assessment of Living Donor Liver Transplantation Systems and Processes of Care

    L. McElroy, J. Holl, A. Daud, M. Abecassis, D. Woods, D. Ladner

    Northwestern University Transplant Research Outcomes Collaborative, Feinberg School of Medicine, Northwestern University, Chicago, IL; Center for Healthcare Studies, Institute for Public Health and Medicine, Northwestern University, Chicago, IL

    Purpose: To identify failures in the handoff from the OR to the intensive care unit (ICU) of living donor liver transplant (LDLT) that lead to…
  • 2013 American Transplant Congress

    CNI-Related Renal Impairment in Liver Transplantation: A Comparison of Cyclosporine and Tacrolimus-Based Regimens

    A. Davie, V. Damera, F. Bianic, J. Ricci, P. Bernhardt, S. Gokhale, J. Lake

    OptumInsight, Uxbridge, United Kingdom; OptumInsight, Nanterre, France; Wellmera AG, Basel, Switzerland; Novartis Pharma AG, Basel, Switzerland; Novartis Healthcare Pvt. Ltd., Hyderabad, India; University of Minnesota, MN

    Background: Long-term and/or high dose exposure to CNI (cyclosporine [CsA] and tacrolimus [Tac]) is associated with high incidence of nephrotoxicity and chronic kidney disease (CKD).Objective:…
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