2013 American Transplant Congress
Tolerogenic Effect of Maternal Microchimerism Is Linked to Semi-Direct Pathway, The
Surgery/Transpantation Division, University of Wisconsin, Madison, WI
Background: In the last decade a semi-direct pathway of alloimune response was described, in which dendritic cells (DC) of the recipient acquire MHC molecules from…2013 American Transplant Congress
Synergism of Complement-Fixing and Non-Complement-Fixing Antibodies to MHC Class I in Pathogenesis of Obliterative Airway Disease: Obligatory Role for the Fc Portion of Immunoglobulins
Washington University, St. Louis, MO
Background: Our previous results demonstrated that both complement fixing (cfABS) as well as non-complement fixing antibodies (ncAbs) to MHC class I result in obliterative airway…2013 American Transplant Congress
Epitope Spreading and Epitope Sharing Are Involved in Acute IgG1 Antibody-Mediated Rejection of a Kidney Transplant with Disparity Only at HLA-DP
University of Toledo, Toledo, OH; University of Pittsburgh, Pittsburgh, PA
Background: Donor-specific alloantibodies (DSA) directed to HLA-DP alone may cause acute antibody-mediated rejection (AMR), especially in re-transplanted patients. Since the origins of such DSA are…2013 American Transplant Congress
Contemporary Analysis of the Effect of Induction Immunosuppression of Survival in Pediatric Lung Transplant Recipients, A
Introduction:The role of induction immunosuppression in lung transplantation (LTX) is varied. In the pediatric population, due to a smaller national incidence and center practice variability,…2013 American Transplant Congress
Effect of CTLA4-Ig on the Fate of Alloreactive Th17 Cells In Vivo, The
Transplantation Research Center, Harvard Medical School, Brigham and Women's Hospital, Boston
The role of Th17:Treg balance in allograft rejection is incompletely understood and remains an active area of investigation. Prior studies have suggested that CD28 costimulation…2013 American Transplant Congress
What Is the Definition of Geographic Equity in Kidney Transplantation?
Northwestern University, Chicago
Purpose: Since the 1990s, a patient’s likelihood of receiving a kidney transplant has highly depended on where a patient resides around the United States. In…2013 American Transplant Congress
Role for DEPTOR in Cell-Intrinsic Mechanisms of Anti-Inflammation in Vascular Endothelial Cells
Recent studies have highlighted a new paradigm whereby the maintenance of normal tissue homeostasis and the prevention of chronic inflammation are dependent on the active…2013 American Transplant Congress
Modification of the Cavaplasty (Hug Procedure) Technique in Liver Transplantation
Westchester Medical Center, Valhalla, NY; First Hospital of Qunming, Qunming, YunNan, China
Introduction: The Cavaplasty OLT, now called Hug Procedure, offers advantages for hepatectomy and implantation and eliminates outflow obstruction. However, caval clamping is required during the…2013 American Transplant Congress
Pharmaceutical Quality and Bioequivalence Assessment of Generic Mycophenolate Mofetil Tablets
Office of Generic Drugs, FDA, Rockville
Purpose. Mycophenolate Mofetil (MMF) is the most used immunosuppressant in solid organ transplantation. Concerns have been raised about substitution between brand and generic MMF tablets.…2013 American Transplant Congress
Behavioral Reference Points in Organ Utilization
Background: Behavioral reference points partition preferences and define the regions over which an outcome is perceived as a “gain” or “loss.” Whether or not behavioral…
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